Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Dirk Lochmann"'
Autor:
Moaaz Abdelhamid, Ioannis Koutsamanis, Carolina Corzo, Mira Maisriemler, Ana Belén Ocampo, Eyke Slama, Carolina Alva, Dirk Lochmann, Sebastian Reyer, Tanja Freichel, Sharareh Salar-Behzadi, Martin Spoerk
Publikováno v:
International journal of pharmaceutics. 624
In order to expand the limited portfolio of available polymer-based excipients for fabricating three-dimensional (3D) printed pharmaceutical products, Lipid-based excipients (LBEs) have yet to be thoroughly investigated. The technical obstacle of LBE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01fe41b64f3fe362d19528e545913910
https://pubmed.ncbi.nlm.nih.gov/35839981
https://pubmed.ncbi.nlm.nih.gov/35839981
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 152
Solid lipid nanoparticles (SLN) are an advantageous carrier system for the delivery of lipophilic active pharmaceutical ingredients (APIs). The use of SLN has been limited due to stability issues attributed to the unstable solid state of the lipid ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed79634512b8a15059989defbc387d50
https://pubmed.ncbi.nlm.nih.gov/32387704
https://pubmed.ncbi.nlm.nih.gov/32387704
Autor:
Andreas Zimmer, Dirk Lochmann, Carolina Corzo, Jesús Alberto Afonso Urich, Agnes Fuchsbichler, Sharareh Salar-Behzadi, Sebastian Reyer, Ioana Savencu
Publikováno v:
International Journal of Pharmaceutics. 610:121259
Spray-drying is an extensively used technology for engineering inhalable particles. Important technical hurdles are however experienced when lipid-based excipients (LBEs) are spray-dried. Stickiness, extensive wall deposition, or simply inability to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d652c09573d2ad6a242022552865df
https://doi.org/10.1016/j.ijpharm.2021.121259
https://doi.org/10.1016/j.ijpharm.2021.121259
Autor:
Sebastian Reyer, Carolina Corzo, Sharareh Salar-Behzadi, Michael Stehr, Dirk Lochmann, Diogo Gomes Lopes
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 148
The major challenge of conventional lipid-based excipients (LBE) for drug delivery is their unstable solid state, affecting the stability of pharmaceutical product. Polyglycerol esters of fatty acids (PGFAs) are oligomeric hydroxyethers of glycerol f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a763e2340e6e9de8fd0adf53cdbecd00
https://pubmed.ncbi.nlm.nih.gov/31982573
https://pubmed.ncbi.nlm.nih.gov/31982573
Autor:
Carolina Corzo, Sharareh Salar-Behzadi, Sebastian Reyer, Claudia Meindl, Kristin Öhlinger, Eleonore Fröhlich, Dirk Lochmann
Publikováno v:
Toxicology and applied pharmacology. 386
One of the main problems for the development of pulmonary formulations is the low availability of approved excipients. Polyglycerol esters of fatty acids (PGFA) are promising molecules for acting as excipient for formulation development and drug deli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a12d7dfe90bef96e95b9c05a1d46dec2
https://pubmed.ncbi.nlm.nih.gov/31756429
https://pubmed.ncbi.nlm.nih.gov/31756429
Autor:
Sebastian Reyer, Brenda Barrios, Valon Demiri, Dirk Lochmann, Julia Karrer, Carolina Corzo, Claudia Meindl, Sharareh Salar-Behzadi
Publikováno v:
Journal of Drug Delivery Science and Technology. 60:102019
This work describes a novel approach for the development of extended release matrix tablets with stable performance via direct compaction. Selected molecules belong to polyglycerol esters of fatty acids (PGFAs) - a group of lipid-based excipients (LB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26647d37cf543cab69f6d438dfea4955
https://doi.org/10.1016/j.jddst.2020.102019
https://doi.org/10.1016/j.jddst.2020.102019
Autor:
Peter Kerschhaggl, Otto Scheibelhofer, Roland Hohl, Detlev Haack, Elena Stocker, Sharareh Salar Behzadi, Stephan Sacher, Andreas Zimmer, Dirk Lochmann, Kai Koch
Publikováno v:
AAPS PharmSciTech. 18:182-193
The aim of the present work was to develop a PAT strategy for the supervision of hot melt coating processes. Optical fibers were placed at various positions in the process chamber of a fluid bed device. Experiments were performed to determine the mos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::456fc6d2de34c93b154d324f21167fb0
https://doi.org/10.1208/s12249-016-0504-4
https://doi.org/10.1208/s12249-016-0504-4
Autor:
Eva-Maria Saurugger, Diogo Gomes Lopes, Diana Kienberger, Karin Becker, Detlev Haack, Michael Stehr, Martin Köberle, Dirk Lochmann, Sharareh Salar-Behzadi, Andreas Zimmer
Publikováno v:
International journal of pharmaceutics. 497(1-2)
Multiparticulate dosage forms are a recent strategy to meet the special needs of children, elderly people and patients suffering from dysphagia. Our study presents a novel and cost-efficient approach for the manufacturing of a taste-masked multiparti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be7d4708b9f34a8c916c32e2c41b0164
https://pubmed.ncbi.nlm.nih.gov/26621689
https://pubmed.ncbi.nlm.nih.gov/26621689
Autor:
Detlev Haack, Dirk Lochmann, Sharareh Salar-Behzadi, Karin Becker, Andreas Zimmer, Diogo Gomes Lopes, Michael Stehr
Publikováno v:
Journal of pharmaceutical sciences. 104(12)
Hot-melt coating is of growing interest, because it does not require solvents, resulting in reduced process times and costs. However, excipients for this technology are mainly triacylglycerides (TAGs) or their derivatives, which exhibit polymorphism,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c58bde9d60f58e32d5efb3c8953b7e5
https://pubmed.ncbi.nlm.nih.gov/26422809
https://pubmed.ncbi.nlm.nih.gov/26422809
Autor:
Jörg Kreuter, Ulrich S. Schubert, Jörg Weyermann, Vitali Vogel, Dieter Schubert, Andreas Zimmer, Jacomina A. van den Broek, Christos Tziatzios, D Daan Wouters, Dirk Lochmann, Gottfried Mayer, Winfried Haase
Publikováno v:
Journal of Controlled Release, 106(1-2), 181-187. Elsevier
Nanoparticles prepared by self-assembly from oligonucleotides (ONs), protamine free base, and human serum albumin (“ternary proticles”) are spheres of diameters around 200 nm. Substitution of the protamine free base by protamine sulfate leads to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8b4c84026c3b00f98882ec14286c225
https://doi.org/10.1016/j.jconrel.2005.04.019
https://doi.org/10.1016/j.jconrel.2005.04.019