Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Dirk Leysen"'
Autor:
Hannah Milh, Kwinten Van Eyck, Bert Bastiaens, Steven De Laet, Dirk Leysen, Deirdre Cabooter, Raf Dewil
Publikováno v:
Water, Vol 12, Iss 6, p 1653 (2020)
The aim of this study was to predict the residual adsorbable organic halides (AOX) concentration in an industrial wastewater using conventional, easy-to-measure wastewater parameters. In a pilot test unit, the wastewater was subjected to ozonation at
Externí odkaz:
https://doaj.org/article/9fc737685e484a9596944daaf45fc322
Autor:
Deirdre Cabooter, Steven De Laet, Kwinten Van Eyck, Dirk Leysen, Bert Bastiaens, Raf Dewil, Hannah Milh
Publikováno v:
Water
Volume 12
Issue 6
Water, Vol 12, Iss 1653, p 1653 (2020)
Volume 12
Issue 6
Water, Vol 12, Iss 1653, p 1653 (2020)
The aim of this study was to predict the residual adsorbable organic halides (AOX) concentration in an industrial wastewater using conventional, easy-to-measure wastewater parameters. In a pilot test unit, the wastewater was subjected to ozonation at
Autor:
Melissa Dullaers, Yves-Paul Vandewynckel, Dirk Leysen, Lien Van den Bossche, Karolien Castermans, Roosmarijn E. Vandenbroucke, Sarah Devriese, Lindsey Devisscher, Riet De Rycke, Karel Geboes, Olivier Defert, Sandro Boland, Arnaud Bourin, Tom Holvoet, Pieter Hindryckx, Martine De Vos, Sophie Van Welden, Debby Laukens
Publikováno v:
Gastroenterology 153 (2017) 4
Gastroenterology, 153(4), 1054-1067
Gastroenterology, 153(4), 1054-1067
Background Intestinal fibrosis resulting in (sub)obstruction is a common complication of Crohn's disease (CD). Rho kinases (ROCKs) play multiple roles in TGFβ-induced myofibroblast activation that could be therapeutic targets. Because systemic ROCK
Autor:
Jessica Vanormelingen, Nicki Boumans, Arnaud Bourin, Sandro Boland, Olivier Defert, Dirk Leysen, Jo Alen, Karolien Castermans, Laura Panitti
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 24:4594-4597
PDE4 inhibitors are of high interest for treatment of a wide range of inflammatory or autoimmune diseases. Their potential however has not yet been realized due to target-associated side effects, resulting in a low therapeutic window. We herein repor
Autor:
Caroline Phillips, R. Armer, N Hawkins, C Jones, Dirk Leysen, Debby Laukens, Tom Holvoet, K Eckersley, Yves-Paul Vandewynckel, Pieter Hindryckx, M. De Vos, Lindsey Devisscher, Olivier Defert, Karel Geboes, Karolien Castermans, M. Bingham, P Bunyard, Sandro Boland, R. De Rycke, Melissa Dullaers, Roosmarijn E. Vandenbroucke, Sarah Devriese, L. Van den Bossche, S. Van Welden, Arnaud Bourin
Publikováno v:
Journal of Crohn's and Colitis. 12:S100-S101
Autor:
T. Roeters, Th. de Boer, J. Steenvoorden, Ralf Plate, J. Wieringa, Dirk Leysen, A. van den Meerendonk, G. Heeres, A. Den Blanken, F. van Bakel, R. Van Der Hulst, H. Rijk
Publikováno v:
Recueil des Travaux Chimiques des Pays-Bas. 112:143-150
A series of 1-[2-[(2-phenoxyphenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines 17–50 (Figure 1) were prepared and tested as inhibitors of biogenic amine re-uptake. In our search for antidepressants, the relationship between their in vitro and in v
Autor:
K. Pieterse, Dirk Leysen, Luc Roumen, Jos F.M. Smits, Judith M. A. Emmen, Peter A. J. Hilbers, Marcel E. de Gooyer, Erica M. G. Custers, Ilona P. E. Beugels, Marijn P. A. Sanders, Harry C. J. Ottenheijm, Johannes Jozeph Robertus Maria Hermans, Ralf Plate
Publikováno v:
Journal of Computer-Aided Molecular Design, 21(8), 455-471. Springer
Journal of Computer-Aided Molecular Design
Journal of Computer-Aided Molecular Design
Aldosterone is synthesised by aldosterone synthase (CYP11B2). CYP11B2 has a highly homologous isoform, steroid 11beta-hydroxylase (CYP11B1), which is responsible for the biosynthesis of aldosterone precursors and glucocorticoids. To investigate aldos
Autor:
Nele Kindt, Arnaud Bourin, Jessica Vanormelingen, Laura Panitti, Jacques Geraets, Jo Alen, Jean Marie Stassen, Karolien Castermans, Silke Fransen, Sandro Boland, Olivier Defert, Nicki Boumans, Pieter Schroeders, Dirk Leysen
Publikováno v:
Journal of medicinal chemistry. 58(10)
ROCK1 and ROCK2 play important roles in numerous cellular functions, including smooth muscle cell contraction, cell proliferation, adhesion, and migration. Consequently, ROCK inhibitors are of interest for treating multiple indications including card
Autor:
Ingeborg Stalmans, Lieve Moons, Evelien Vandewalle, Karolien Castermans, Tine Van Bergen, Karolien Hollanders, Nele Kindt, Dirk Leysen
Publikováno v:
Investigative ophthalmologyvisual science. 56(2)
PURPOSE Rho kinase (ROCK) is associated with VEGF-driven angiogenesis, as well as with inflammation and fibrosis. Therefore, the effect of AMA0428, a novel ROCK inhibitor, was studied in these processes, which highly contribute to the pathogenesis of
Autor:
Dirk Leysen, Helenius J. Kloosterboer, Hendrika M. Oppers-Tiemissen, Herman A. M. Verheul, Marcel E. de Gooyer
Publikováno v:
Steroids. 68:235-243
To exclude that aromatization plays a role in the estrogenic activity of tibolone, we studied the effect tibolone and metabolites on the aromatization of androstenedione and the aromatization of tibolone and its metabolites to 7alpha-methyl-17alpha-e