Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Dirk Kraus"'
Autor:
Christoph M. Ernst, Sebastian Kuhn, Christoph J. Slavetinsky, Bernhard Krismer, Simon Heilbronner, Cordula Gekeler, Dirk Kraus, Samuel Wagner, Andreas Peschel
Publikováno v:
mBio, Vol 6, Iss 1 (2015)
ABSTRACT Phospholipids are synthesized at the inner leaflet of the bacterial cytoplasmic membrane but have to be translocated to the outer leaflet to maintain membrane lipid bilayer composition and structure. Even though phospholipid flippases have b
Externí odkaz:
https://doaj.org/article/eaa22c27ed4c493c9d617225a249e9ec
Autor:
Christoph M Ernst, Petra Staubitz, Nagendra N Mishra, Soo-Jin Yang, Gabriele Hornig, Hubert Kalbacher, Arnold S Bayer, Dirk Kraus, Andreas Peschel
Publikováno v:
PLoS Pathogens, Vol 5, Iss 11, p e1000660 (2009)
Many bacterial pathogens achieve resistance to defensin-like cationic antimicrobial peptides (CAMPs) by the multiple peptide resistance factor (MprF) protein. MprF plays a crucial role in Staphylococcus aureus virulence and it is involved in resistan
Externí odkaz:
https://doaj.org/article/7b54c60984224552b543a9bc9335bdee
Autor:
Silvia Herbert, Agnieszka Bera, Christiane Nerz, Dirk Kraus, Andreas Peschel, Christiane Goerke, Michael Meehl, Ambrose Cheung, Friedrich Götz
Publikováno v:
PLoS Pathogens, Vol 3, Iss 7, p e102 (2007)
It has been shown recently that modification of peptidoglycan by O-acetylation renders pathogenic staphylococci resistant to the muramidase activity of lysozyme. Here, we show that a Staphylococcus aureus double mutant defective in O-acetyltransferas
Externí odkaz:
https://doaj.org/article/f0a7f6c2667942feb8abe3da2703f594
Autor:
Joanna H. Bonczarowska, Julian Susat, Barbara Mühlemann, Isabelle Jasch-Boley, Sebastian Brather, Benjamin Höke, Susanne Brather-Walter, Valerie Schoenenberg, Jonathan Scheschkewitz, Gabriele Graenert, Dirk Krausse, Michael Francken, Terry C. Jones, Joachim Wahl, Almut Nebel, Ben Krause-Kyora
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-16 (2022)
Abstract Background The pathogen landscape in the Early European Middle Ages remains largely unexplored. Here, we perform a systematic pathogen screening of the rural community Lauchheim “Mittelhofen,” in present-day Germany, dated to the Merovin
Externí odkaz:
https://doaj.org/article/4b05cb5d83f740778e9bcd5eee5ed1ed
Publikováno v:
Journal of Bacteriology. 190:3419-3428
The two-component system SaeRS of Staphylococcus aureus is closely involved in the regulation of major virulence factors. However, little is known about the signals leading to saeRS activation. A total of four overlapping transcripts (T1 to T4) from
Autor:
Dirk Kraus, Belén López-García, Robert A. Dorschner, Victor Nizet, Richard L. Gallo, Andreas Peschel, Kazuya Morikawa
Publikováno v:
The FASEB Journal. 20:35-42
Antimicrobial peptides (AMPs) have been shown in animal and human systems to be effective natural antibiotics. However, it is unclear how they convey protection; they often appear inactive when assayed under culture conditions applied to synthetic an
Autor:
Nagendra N. Mishra, Arnold S. Bayer, Soo-Jin Yang, Gabriele Hornig, Petra Staubitz, Christoph M. Ernst, Hubert Kalbacher, Dirk Kraus, Andreas Peschel
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 5, Iss 11, p e1000660 (2009)
PLoS Pathogens, Vol 5, Iss 11, p e1000660 (2009)
Many bacterial pathogens achieve resistance to defensin-like cationic antimicrobial peptides (CAMPs) by the multiple peptide resistance factor (MprF) protein. MprF plays a crucial role in Staphylococcus aureus virulence and it is involved in resistan
Autor:
Dirk Kraus, Andreas Peschel
Publikováno v:
Future microbiology. 3(4)
Bacterial pathogens colonize human body surfaces soon after birth. In order to survive the constant threat of invasion and infection, the human innate immune system has evolved several efficient mechanisms to prevent harmful microorganisms from trave
Autor:
Andreas Peschel, Silvia Herbert, Sascha A. Kristian, Victor Nizet, Friedrich Götz, Dirk Kraus, Arya Khosravi
Publikováno v:
BMC Microbiology, Vol 8, Iss 1, p 85 (2008)
BMC Microbiology
BMC Microbiology
Background Modification of teichoic acids with D-alanine by the products of the dlt operon protects Gram-positive bacteria against major antimicrobial host defense molecules such as defensins, cathelicidins, myeloperoxidase or phospholipase. The gra
Autor:
Dirk Kraus, Erwin Bohn, Kirill Essin, Ralph Kettritz, Peter Ruth, Birgit Salanova, Friedrich C. Luft, Ingo B. Autenrieth, Andreas Peschel, Matthias Sausbier, Maik Gollasch
Publikováno v:
American journal of physiology. Cell physiology. 293(1)
Large-conductance Ca2+-activated K+(BK) channels are reported to be essential for NADPH oxidase-dependent microbial killing and innate immunity in leukocytes. Using human peripheral blood and mouse bone marrow neutrophils, pharmacological targeting,