Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Dirk Kluth"'
Publikováno v:
European Journal of Nutrition. 43:336-343
Carotenoids are important micronutrients in the human diet and are present in human serum at micromolar concentrations. In addition to their antioxidant potential, carotenoids obtain physiologically relevant properties such as influencing cellular si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::492bd66b5f538d9fd2d4c1a60500873b
https://doi.org/10.1007/s00394-004-0475-1
https://doi.org/10.1007/s00394-004-0475-1
Autor:
Dirk Kluth, Hansruedi Glatt, Regina Brigelius-Flohé, Nico Landes, Gaby-Fleur Böl, Ralph Rühl, Marc Birringer, Paul T. Pfluger
Publikováno v:
Biochemical Pharmacology. 65:269-273
Tocopherols and tocotrienols are metabolized by side chain degradation via initial omega-oxidation and subsequent beta-oxidation. omega-Oxidation is performed by cytochrome P450 (CYP) enzymes which are often regulated by their substrates themselves.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfdf5e79a98098f44abfd89421322987
https://doi.org/10.1016/s0006-2952(02)01520-4
https://doi.org/10.1016/s0006-2952(02)01520-4
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
The metabolism of alpha- and gamma-tocotrienol was investigated in HepG2 cells. Metabolites were identified by HPLC and gas chromatography/mass spectrometry. gamma-Tocotrienol was degraded to gamma-CEHC (carboxyethyl hydroxychroman), gamma-CMBHC (car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::633ce21538680fc95b003dac819aa005
https://doi.org/10.1093/jn/131.10.3113
https://doi.org/10.1093/jn/131.10.3113
Autor:
Claus Schneider, Oliver Mann, Dirk Kluth, Christian Bloechle, Emre F. Yekebas, Jakob R. Izbicki, Tim Strate, Jussuf T. Kaifi, Wolf-Jonas Tiefenbacher
Publikováno v:
Pancreas. 38(1)
Objectives Platelet-activating factor (PAF) is an important mediator of inflammation and postulated to be involved in the pathogenesis of acute pancreatitis. In this study, we evaluated the therapeutic effect of PAF antagonist WEB 2086 in acute exper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a212f42b11f21535e0070dc97200109
https://pubmed.ncbi.nlm.nih.gov/18695628
https://pubmed.ncbi.nlm.nih.gov/18695628
Publikováno v:
Free radical biologymedicine. 42(3)
Based on animal models, dietary polyphenols are predicted to be promising chemopreventive agents in humans. Allspice, clove, and thyme extracts as well as defined dietary polyphenolic compounds were, therefore, tested for their ability to activate me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d27c7ce54bd43968cd377eee48d29e1d
https://pubmed.ncbi.nlm.nih.gov/17210444
https://pubmed.ncbi.nlm.nih.gov/17210444
Publikováno v:
Molecular nutritionfood research. 49(11)
Antioxidants, preferentially those of dietary origin, have for a long time been considered to help against diseases that are presumably aggravated by oxidative stress, such as cardiovascular diseases, cancer, and neurodegenerative disorders. The outc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::187f6eb7f75593ca89d4f7470b8ac5c1
https://pubmed.ncbi.nlm.nih.gov/16270281
https://pubmed.ncbi.nlm.nih.gov/16270281
Publikováno v:
Molecular and cellular biology. 25(12)
The gastrointestinal glutathione peroxidase (GI-GPx, GPx2) is a selenoprotein that was suggested to act as barrier against hydroperoxide absorption but has also been implicated in the control of inflammation and malignant growth. In CaCo-2 cells, GI-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fed3fd562c50e4ef329a0e5a2eb7052c
https://pubmed.ncbi.nlm.nih.gov/15923610
https://pubmed.ncbi.nlm.nih.gov/15923610
Publikováno v:
Redox report : communications in free radical research. 9(5)
Some 80 years after its discovery, vitamin E has experienced a renaissance which is as surprising as it is trivial. Although vitamin E is essential for reproduction, in rats at least, and deficiency causes neurological disorders in humans, the main i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d361837518a0bd53270835b72c43a30
https://pubmed.ncbi.nlm.nih.gov/15606977
https://pubmed.ncbi.nlm.nih.gov/15606977
Publikováno v:
GBM Annual Spring meeting Mosbach 2004. 2004
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcfc5e47bd9f6033d9af06b4d2cd6319
https://doi.org/10.1240/sav_gbm_2004_m_000454
https://doi.org/10.1240/sav_gbm_2004_m_000454
Autor:
Paul T. Pfluger, Katrin Mller-Schmehl, Christiane Bumke-Vogt, Nico Landes, Regina Brigelius-Floh, Dirk Kluth
Publikováno v:
GBM Annual Spring meeting Mosbach 2004. 2004
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1458370cd875cbd84e076ced51721099
https://doi.org/10.1240/sav_gbm_2004_m_000463
https://doi.org/10.1240/sav_gbm_2004_m_000463