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Akademický článek

'shortCardiac' — An open-source framework for fast and standardized assessment of cardiac function

Autor: Karl Ludger Radke, Janina Hußmann, Lena Röwer, Dirk Voit, Jens Frahm, Gerald Antoch, Dirk Klee, Frank Pillekamp, Hans-Jörg Wittsack

Publikováno v: SoftwareX, Vol 23, Iss , Pp 101453- (2023)

In medicine, especially in radiology, artificial intelligence has sparked a growing interest in automated systems, image analysis, and acquisition standardization. In the wake of this standardization, the research field of “radiomics” has gained

Externí odkaz: https://doaj.org/article/8a5cebca3c754b00a4eaebceabc50eeb

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Akademický článek

Neuroimaging in Primary Coenzyme-Q10-Deficiency Disorders

Autor: Juliane Münch, Jannik Prasuhn, Lucia Laugwitz, Cheuk-Wing Fung, Brian H.-Y. Chung, Marcello Bellusci, Ertan Mayatepek, Dirk Klee, Felix Distelmaier

Publikováno v: Antioxidants, Vol 12, Iss 3, p 718 (2023)

Coenzyme Q10 (CoQ10) is an endogenously synthesized lipid molecule. It is best known for its role as a cofactor within the mitochondrial respiratory chain where it functions in electron transfer and ATP synthesis. However, there are many other cellul

Externí odkaz: https://doaj.org/article/32df7fb6fc4f4a64a575318dfcfb0499

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Akademický článek

Deep Learning-Based Post-Processing of Real-Time MRI to Assess and Quantify Dynamic Wrist Movement in Health and Disease

Autor: Karl Ludger Radke, Lena Marie Wollschläger, Sven Nebelung, Daniel Benjamin Abrar, Christoph Schleich, Matthias Boschheidgen, Miriam Frenken, Justus Schock, Dirk Klee, Jens Frahm, Gerald Antoch, Simon Thelen, Hans-Jörg Wittsack, Anja Müller-Lutz

Publikováno v: Diagnostics, Vol 11, Iss 6, p 1077 (2021)

While morphologic magnetic resonance imaging (MRI) is the imaging modality of choice for the evaluation of ligamentous wrist injuries, it is merely static and incapable of diagnosing dynamic wrist instability. Based on real-time MRI and algorithm-bas

Externí odkaz: https://doaj.org/article/c277788aee0744a6ba5b1d28e3dd3ceb

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Akademický článek

Fluorescence optical imaging and musculoskeletal ultrasonography in juvenile idiopathic polyarticular disease before and during antirheumatic treatment - a multicenter non-interventional diagnostic evaluation

Autor: Ariane Klein, Georg Werner Just, Stephanie Gabriele Werner, Prasad T. Oommen, Kirsten Minden, Ingrid Becker, Hans-Eckhard Langer, Dirk Klee, Gerd Horneff

Publikováno v: Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-12 (2017)

Abstract Background Valid detection of inflamed joints is essential for correct classification, therapeutic decisions, prognosis and assessment of treatment efficacy in juvenile idiopathic arthritis (JIA). Fluorescence optical imaging (FOI) enables v

Externí odkaz: https://doaj.org/article/e83ad2aa141b42fab6614fcac0d68325

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Akademický článek

Treatment with long-acting lanreotide autogel in early infancy in patients with severe neonatal hyperinsulinism

Autor: Heike Corda, Sebastian Kummer, Alena Welters, Norbert Teig, Dirk Klee, Ertan Mayatepek, Thomas Meissner

Publikováno v: Orphanet Journal of Rare Diseases, Vol 12, Iss 1, Pp 1-8 (2017)

Abstract Background Treatment of severe diffuse congenital hyperinsulinism (CHI) without sufficient response to diazoxide is complicated by the lack of approved drugs. Therefore, patients are often hospitalized long-term or have to undergo pancreatic

Externí odkaz: https://doaj.org/article/49e320241c924fe7acaa0b3b020eec50

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Comparison of cardiac volumetry using real-time MRI during free-breathing with standard cine MRI during breath-hold in children

Autor: Lena Maria Röwer, Karl Ludger Radke, Janina Hußmann, Halima Malik, Tobias Uelwer, Dirk Voit, Jens Frahm, Hans-Joerg Wittsack, Stefan Harmeling, Frank Pillekamp, Dirk Klee

Publikováno v: Pediatric Radiology

Background Cardiac real-time magnetic resonance imaging (RT-MRI) provides high-quality images even during free-breathing. Difficulties in post-processing impede its use in clinical routine. Objective To demonstrate the feasibility of quantitative ana

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54668eefe4ae0e4e5e7aa39fa85f9e9c
https://hdl.handle.net/21.11116/0000-000A-8EE9-021.11116/0000-000A-8EEB-E

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Entwicklung der Kinder- und Jugendradiologie – Strategiepapier des Vorstands der Gesellschaft für Pädiatrische Radiologie (GPR e. V.)

Autor: Sandra Habernig, Juergen F. Schaefer, Hans-Joachim Mentzel, Gerald Antoch, Gabriele Hahn, Andreas Leenen, Friederike Koerber, Dirk Klee, Mark Born, Michael Riccabona, Thekla von Kalle, Gundula Staatz

Publikováno v: RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren. 192:531-536

Das Strategiepapier der GPR zeigt Entwicklungsmöglichkeiten der Kinder- und Jugendradiologie als Querschnittsfach zwischen der Radiologie und der konservativen und operativen Kinder- und Jugendmedizin auf. Zitierweise

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::30a32fbdea3f495fe7565603f2745a93
https://doi.org/10.1055/a-1103-2339

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Bi-allelic Variants in RALGAPA1 Cause Profound Neurodevelopmental Disability, Muscular Hypotonia, Infantile Spasms, and Feeding Abnormalities

Publikováno v: American journal of human genetics, vol 106, iss 2
Am. J. Hum. Genet. 106, 246-255 (2020)
Am J Hum Genet

Ral (Ras-like) GTPases play an important role in the control of cell migration and have been implicated in Ras-mediated tumorigenicity. Recently, variants in RALA were also described as a cause of intellectual disability and developmental delay, indi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95041cccfffd6637b1514b42458bbb95
https://doi.org/10.1016/j.ajhg.2020.01.002

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