Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Dirk Haubert"'
Autor:
Carola Pongratz, Jens M. Seeger, Benjamin Yazdanpanah, Dirk Haubert, Hamid Kashkar, Martin Krönke, Oliver Coutelle, Kerstin Brinkmann
Publikováno v:
British Journal of Cancer
Background: In various tumour types, elevated expression of the X-linked inhibitor of apoptosis protein (XIAP) has been observed and XIAP targeting in diverse tumour entities enhanced the susceptibility to chemotherapeutic agents. Therefore, XIAP has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ec5592c632adb5667b75f86c74bf77a
https://doi.org/10.1038/sj.bjc.6605704
https://doi.org/10.1038/sj.bjc.6605704
Publikováno v:
Journal of Cell Science. 122:1939-1946
Tumour necrosis factor α (TNFα) is a pro-inflammatory mediator with the capacity to induce apoptosis. An integral part of its apoptotic and inflammatory programmes is the control of cell shape through modulation of the cytoskeleton, but it is now b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9db5283c28e637a5a6494f9bfedb9965
https://doi.org/10.1242/jcs.044487
https://doi.org/10.1242/jcs.044487
Autor:
Barbara Metzler, Jianping Li, Thomas Calzascia, Daniel Kaiser, Dirk Haubert, Gisbert Weckbecker, Esther Sutter, Victor L. J. Tybulewicz, Alexander Saveliev
Publikováno v:
Transplant Immunology
The GDP exchange factor (GEF) Vav1 is a central signal transducer downstream of the T cell receptor and has been identified as a key factor for T cell activation in the context of allograft rejection. Vav1 has been shown to transduce signals both dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d0004d2bd36bad86bed16ad4840a4da
https://pubmed.ncbi.nlm.nih.gov/22456277
https://pubmed.ncbi.nlm.nih.gov/22456277
Autor:
Gisbert Weckbecker, Dirk Haubert
Publikováno v:
Cellular signalling. 22(6)
The transcription factor cAMP-responsive element binding protein (CREB) is a regulator of the expression of several genes important for lymphocyte activation and proliferation. However, the proximal signaling events leading to activation of CREB in T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a9c707fe3a0c5407acea3ae9444a843
https://pubmed.ncbi.nlm.nih.gov/20138987
https://pubmed.ncbi.nlm.nih.gov/20138987
Autor:
Nina Gharib, Marianna Hösel, Francisco Rivero, Martin Krönke, Katja Wiegmann, Dirk Haubert, Hamid Kashkar
The WD-repeat protein factor associated with nSMase activity (FAN) is a member of the family of TNF receptor adaptor proteins that are coupled to specific signaling cascades. However, the precise functional involvement of FAN in specific cellular TNF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1621b144fb48a1d23ca9bc70610320b6
https://europepmc.org/articles/PMC1933409/
https://europepmc.org/articles/PMC1933409/
Autor:
Martin Krönke, Anke Deggerich, Carola Pongratz, Dirk Haubert, Katja Wiegmann, Hamid Kashkar, Jens-Michael Seeger, Benjamin Yazdanpanah
Publikováno v:
Blood. 109(9)
The proteasome inhibitor bortezomib has been shown to possess promising antitumor activity and significant efficacy against a variety of malignancies. Different studies demonstrated that bortezomib breaks the chemoresistance in different tumor cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ada36aba82127bfc439b12cd60f5b530
https://pubmed.ncbi.nlm.nih.gov/17185461
https://pubmed.ncbi.nlm.nih.gov/17185461
Publikováno v:
The Journal of biological chemistry. 280(21)
Ultraviolet light-induced apoptosis can be caused by DNA damage but also involves immediate-early cell death cascades characteristic of death receptor signaling. Here we show that the UV light-induced apoptotic signaling pathway is unique, targeting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::449ed5fc8276cb214f63a3efb5c043c0
https://pubmed.ncbi.nlm.nih.gov/15743760
https://pubmed.ncbi.nlm.nih.gov/15743760