Výsledky vyhledávání - "Dirk H. S. M. Schellekens"

Akademický článek

Evaluating the safety of two human experimental intestinal ischemia reperfusion models: A retrospective observational study.

Autor: Inca H R Hundscheid, Dirk H S M Schellekens, Joep Grootjans, Marcel Den Dulk, Ronald M Van Dam, Geerard L Beets, Wim A Buurman, Kaatje Lenaerts, Joep P M Derikx, Cornelis H C Dejong

Publikováno v: PLoS ONE, Vol 16, Iss 6, p e0253506 (2021)

BackgroundWe developed a jejunal and colonic experimental human ischemia-reperfusion (IR) model to study pathophysiological intestinal IR mechanisms and potential new intestinal ischemia biomarkers. Our objective was to evaluate the safety of these I

Externí odkaz: https://doaj.org/article/fe55f9ae98a648f184efc56f55753e21

Zobrazit plný text záznamu

Females Are More Resistant to Ischemia-Reperfusion-induced Intestinal Injury Than Males A Human Study

Autor: Cornelis H. C. Dejong, Dirk H. S. M. Schellekens, Joep Grootjans, Joep P. M. Derikx, Wim A. Buurman, Inca H.R. Hundscheid, Kaatje Lenaerts

Publikováno v: Hundscheid, I H R, Schellekens, D H S M, Grootjans, J, Derikx, J P M, Buurman, W A, Dejong, C H C & Lenaerts, K 2020, ' Females Are More Resistant to Ischemia-Reperfusion-induced Intestinal Injury Than Males: A Human Study ', Annals of Surgery, vol. 272, no. 6, pp. 1070-1079 . https://doi.org/10.1097/SLA.0000000000003167
Annals of surgery, 272(6), 1070-1079. Lippincott Williams and Wilkins
Annals of Surgery, 272(6), 1070-1079. Lippincott Williams and Wilkins
Annals of Surgery, 272(6), 1070-1079. LIPPINCOTT WILLIAMS & WILKINS

Background and Objective: Sex differences in responses to intestinal ischemia-reperfusion (IR) have been recognized in animal studies. We aimed to investigate sexual dimorphism in human small intestinal mucosal responses to IR. Methods: In 16 patient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3314450e5dfe41726a6985a3703bb5aa
https://doi.org/10.1097/sla.0000000000003167

Zobrazit plný text záznamu

Evaluating the safety of two human experimental intestinal ischemia reperfusion models

Autor: Wim A. Buurman, Joep Grootjans, Inca H R Hundscheid, Dirk H. S. M. Schellekens, Joep P. M. Derikx, Kaatje Lenaerts, Ronald M. Van Dam, Geerard L. Beets, Marcel den Dulk, Cornelis H. C. Dejong

Publikováno v: PLoS ONE
PLoS ONE, Vol 16, Iss 6, p e0253506 (2021)
PLOS ONE, 16(6):0253506. Public Library of Science
PLOS ONE 16(6), 0253506 (2021). doi:10.1371/journal.pone.0253506
PLoS ONE, 16(6 June):e0253506. Public Library of Science

PLOS ONE 16(6), 0253506 (2021). doi:10.1371/journal.pone.0253506
Published by PLOS, San Francisco, California, US

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07a9aa2364347dd492e7b46da5615ef1
https://cris.maastrichtuniversity.nl/en/publications/57ff6f10-88e4-49d5-b3a4-a855c0a2a460

Zobrazit plný text záznamu

Serological markers for human intestinal ischemia

Autor: Stefan Acosta, Joep P. M. Derikx, Dirk H. S. M. Schellekens

Publikováno v: Derikx, J P M, Schellekens, D H S M & Acosta, S 2017, ' Serological markers for human intestinal ischemia : A systematic review ', Best Practice and Research: Clinical Gastroenterology, vol. 31, no. 1, pp. 69-74 . https://doi.org/10.1016/j.bpg.2017.01.004

Early and accurate diagnosis of intestinal ischemia is important in order to provide rapid and correct treatment and reduce morbidity and mortality rates. Clinical signs and symptoms are often unspecific. This systemic review sums up literature regar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db0fb8c476f5a78d53ae2a933129bf82
https://doi.org/10.1016/j.bpg.2017.01.004

Zobrazit plný text záznamu

Human splanchnic amino-acid metabolism

Autor: S. W. M. Olde Damink, Siamack Sabrkhany, Kaatje Lenaerts, Evelien P. J. G. Neis, Ellen E. Blaak, Dirk H. S. M. Schellekens, Sander S. Rensen, Inca H.R. Hundscheid, Cornelis H. C. Dejong

Publikováno v: Amino Acids, 49(1), 161-172. Springer
Amino Acids

Plasma levels of several amino acids are correlated with metabolic dysregulation in obesity and type 2 diabetes. To increase our understanding of human amino-acid metabolism, we aimed to determine splanchnic interorgan amino-acid handling. Twenty pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c164c467efeff7fb31f7e3268168f10
https://cris.maastrichtuniversity.nl/en/publications/fa8746ef-efcd-455c-a4b7-35bf39174fa3

Zobrazit plný text záznamu

Human small intestine is capable of restoring barrier function after short ischemic periods

Autor: Inca H.R. Hundscheid, Claire A. J. I. Leenarts, Joep P. M. Derikx, Joep Grootjans, Wim A. Buurman, Dirk H. S. M. Schellekens, Kaatje Lenaerts, Cornelis H. C. Dejong

Publikováno v: Schellekens, D H, Hundscheid, I H, Leenarts, C A, Grootjans, J, Lenaerts, K, Buurman, W A, Dejong, C H & Derikx, J P 2017, ' Human small intestine is capable of restoring barrier function after short ischemic periods ', World Journal of Gastroenterology, vol. 23, no. 48, pp. 8452-8464 . https://doi.org/10.3748/wjg.v23.i48.8452
World journal of gastroenterology, 23(48), 8452-8464. WJG Press
World Journal of Gastroenterology, 23(48), 8452-8464. Baishideng Publishing Group Inc
World Journal of Gastroenterology
World Journal of Gastroenterology, 23(48), 8452-8464. WJG Press

AIMTo assess intestinal barrier function during human intestinal ischemia and reperfusion (IR).METHODSIn a human experimental model, 6 cm of jejunum was selectively exposed to 30 min of ischemia (I) followed by 30 and 120 min of reperfusion (R). A sh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60e74837ed5600d1307ba071df28cd4f
https://doi.org/10.3748/wjg.v23.i48.8452

Zobrazit plný text záznamu

SM22 a Plasma Biomarker for Human Transmural Intestinal Ischemia

Autor: Kostan W. Reisinger, Steven W.M. Olde Damink, M'hamed Hadfoune, Wim A. Buurman, Dirk H. S. M. Schellekens, Joep P. M. Derikx, Kaatje Lenaerts, Cornelis H. C. Dejong

Publikováno v: Annals of Surgery, 268(1), 120-126. Lippincott Williams and Wilkins
Schellekens, D H S M, Reisinger, K W, Lenaerts, K, Hadfoune, M, Olde Damink, S W, Buurman, W A, Dejong, C H C & Derikx, J P M 2018, ' SM22 a Plasma Biomarker for Human Transmural Intestinal Ischemia ', Annals of Surgery, vol. 268, no. 1, pp. 120-126 . https://doi.org/10.1097/SLA.0000000000002278
Annals of surgery, 268(1), 120-126. Lippincott Williams and Wilkins
Annals of Surgery, 268(1), 120-126. LIPPINCOTT WILLIAMS & WILKINS

OBJECTIVE: To evaluate the diagnostic potential of smooth muscle protein of 22 kDa (SM22) as plasma biomarker for the detection of transmural intestinal ischemia.BACKGROUND: Acute mesenteric ischemia is an abdominal emergency requiring rapid diagnosi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f281be97aabd034b4bee85c352aebc01
https://research.vumc.nl/en/publications/80142b0a-370c-47f4-a0d3-324672a2d0b6

Zobrazit plný text záznamu

Response: 'Early Acute Mesenteric Ischemia: Many Rivers to Cross'

Autor: Dirk H. S. M. Schellekens, Joep P. M. Derikx, Wim A. Buurman, Cornelis H. C. Dejong

Publikováno v: Schellekens, D H S M, Buurman, W A, Dejong, C H C & Derikx, J P M 2018, ' Response: "Early Acute Mesenteric Ischemia: Many Rivers to Cross" ', Annals of Surgery, vol. 268, no. 6, pp. e42-e43 . https://doi.org/10.1097/SLA.0000000000002498
Annals of Surgery, 268(6), E42-E43. LIPPINCOTT WILLIAMS & WILKINS
Annals of surgery, 268(6), e42-e43. Lippincott Williams and Wilkins
Annals of Surgery, 268(6), e42-e43. Lippincott Williams and Wilkins

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e5786f026d00e219456879d5e28023b
https://research.vumc.nl/en/publications/f4b4e842-db15-4ff7-a151-c486f9f0e4e5

Zobrazit plný text záznamu

The Human Colon Is More Resistant to Ischemia-reperfusion-induced Tissue Damage Than the Small Intestine An Observational Study

Autor: Bas Boonen, Wim A. Buurman, Maarten F. von Meyenfeldt, Cornelis H. C. Dejong, Kaatje Lenaerts, Geerard L. Beets, Joep Grootjans, Dirk H. S. M. Schellekens, Joep P. M. Derikx, Inca H.R. Hundscheid

Publikováno v: Annals of Surgery, 262(2), 304-311. LIPPINCOTT WILLIAMS & WILKINS
Annals of surgery, 262(2), 304-311. Lippincott Williams and Wilkins

OBJECTIVE: Aim of this study was to draw comparisons between human colonic and jejunal ischemia-reperfusion sequelae in a human in vivo experimental model. BACKGROUND: In patients, colonic ischemia-reperfusion generally has a milder course than small

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22bc09c66959bd390b6e6008efe0cfcd
https://doi.org/10.1097/sla.0000000000001131

Zobrazit plný text záznamu

Cyclooxygenase-2 Is Essential for Colorectal Anastomotic Healing

Autor: Martijn Poeze, Joanna W. A. M. Bosmans, Prapto Sastrowijoto, Dirk H. S. M. Schellekens, Joep Grootjans, Kostan W. Reisinger, Bas Boonen, Joep P. M. Derikx, Karel W.E. Hulsewé

Publikováno v: Annals of Surgery, 265(3), 547-554. LIPPINCOTT WILLIAMS & WILKINS
Reisinger, K W, Schellekens, D H S M, Bosmans, J W A M, Boonen, B, Hulsewé, K W E, Sastrowijoto, P, Derikx, J P M, Grootjans, J & Poeze, M 2017, ' Cyclooxygenase-2 Is Essential for Colorectal Anastomotic Healing ', Annals of Surgery, vol. 265, no. 3, pp. 547-554 . https://doi.org/10.1097/SLA.0000000000001744
Annals of surgery, 265(3), 547-554. Lippincott Williams and Wilkins
Annals of Surgery, 265(3), 547-554. Lippincott Williams and Wilkins

Objective: To study the effects of COX-2 on colonic surgical wound healing.Background: Cyclooxygenase-2 (COX-2) is a key enzyme in gastrointestinal homeostasis. COX-2 inhibitors have been associated with colonic anastomotic leakage.Methods: Wildtype,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::916b74d78007d640e60d656c9d0096fb
https://cris.maastrichtuniversity.nl/en/publications/16461515-51f5-4cc4-b768-30d8953f7cfa

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání