Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Dirk Fasshauer"'
BET1 variants establish impaired vesicular transport as a cause for muscular dystrophy with epilepsy
Autor:
Sandra Donkervoort, Niklas Krause, Mykola Dergai, Pomi Yun, Judith Koliwer, Svetlana Gorokhova, Janelle Geist Hauserman, Beryl B Cummings, Ying Hu, Rosemarie Smith, Prech Uapinyoying, Vijay S Ganesh, Partha S Ghosh, Kristin G Monaghan, Seby L Edassery, Pia E Ferle, Sarah Silverstein, Katherine R Chao, Molly Snyder, Sara Ellingwood, Diana Bharucha‐Goebel, Susan T Iannaccone, Matteo Dal Peraro, A Reghan Foley, Jeffrey N Savas, Véronique Bolduc, Dirk Fasshauer, Carsten G Bönnemann, Michael Schwake
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 12, Pp 1-17 (2021)
Abstract BET1 is required, together with its SNARE complex partners GOSR2, SEC22b, and Syntaxin‐5 for fusion of endoplasmic reticulum‐derived vesicles with the ER‐Golgi intermediate compartment (ERGIC) and the cis‐Golgi. Here, we report three
Externí odkaz:
https://doaj.org/article/36e02f0c64b8417881fabf19320857cf
Autor:
Jörn M. Völker, Mykola Dergai, Luciano A. Abriata, Yves Mingard, Daniel Ysselstein, Dimitri Krainc, Matteo Dal Peraro, Gabriele Fischer von Mollard, Dirk Fasshauer, Judith Koliwer, Michael Schwake
Publikováno v:
Disease Models & Mechanisms, Vol 10, Iss 12, Pp 1391-1398 (2017)
Progressive myoclonus epilepsies (PMEs) are inherited disorders characterized by myoclonus, generalized tonic-clonic seizures, and ataxia. One of the genes that is associated with PME is the ER-to-Golgi Qb-SNARE GOSR2, which forms a SNARE complex wit
Externí odkaz:
https://doaj.org/article/7144d805276745b29e2b76a780c76495
Autor:
Dirk Fasshauer
It has been proposed that arachidonic acid stimulates neurite outgrowth by specifically activating syntaxin 3, a SNARE proteins that mediates the fusion of transport vesicles with the plasma membrane and is thus instrumental for the insertion of new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e98a4564fe002a33dccc50773eeb7a9
https://doi.org/10.1101/2023.02.06.527244
https://doi.org/10.1101/2023.02.06.527244
Neurotransmitters are released from synaptic vesicles, the membrane of which fuses with the plasma membrane upon calcium influx. This membrane fusion reaction is driven by the formation of a tight complex comprising the plasma membrane SNARE proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::028fa2b354477521212f655e88892615
https://doi.org/10.1101/2022.11.29.518383
https://doi.org/10.1101/2022.11.29.518383
Autor:
Leonid L. Moroz, Daria Y. Romanova, Jean Daraspe, Mikhail A. Nikitin, Dirk Fasshauer, Frederique Varoqueaux, Michael Eitel
Publikováno v:
Cell Tissue Res
From a morphological point of view, placozoans are among the most simple free-living animals. This enigmatic phylum is critical for our understanding of the evolution of animals and their cell types. Their millimeter-sized, disc-like bodies consist o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49d6e02cfd1b24aec47127cefe5f6570
https://doi.org/10.1007/s00441-021-03459-y
https://doi.org/10.1007/s00441-021-03459-y
Autor:
Gabriela Caraveo, Kim A. Caldwell, Jessica Lacoste, Yongbo Zhang, Damian B. van Rossum, Marco Tonelli, Sergei Kuchin, Aishwarya Shevade, Sofia Zaichick, Anthony L. Gaeta, Guy A. Caldwell, Daayun Chung, Mikko Taipale, Jeffrey N. Savas, Shivani Agarwal, Dirk Fasshauer, G. Wiersum, Kaitlyn McGrath, Ludmilla Shuvalova, Wenyu Wen, Mykola Dergai, Andrew K. Shum
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 12, pp. e2016730118
Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 12, pp. e2016730118
Significance Ykt6 is a conserved SNARE that plays critical roles along multiple vesicular pathways. To achieve its function, Ykt6 cycles between the cytosol and membrane-bound compartments through reversible lipidation. The mechanism that regulates t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4bd0e23041df6f7c5e6861afa9cb4ac
http://europepmc.org/articles/PMC8000380
http://europepmc.org/articles/PMC8000380
Autor:
Daria Y. Romanova, Leonid L. Moroz, Michael Eitel, Dirk Fasshauer, Jean Daraspe, Mikhail A. Nikitin, Frederique Varoqueaux
From a morphological point of view, placozoans are among the most simple free-living animals. This enigmatic phylum is critical for our understanding of the evolution of animals and their cell types. Their millimeter-sized, disc-like bodies consist o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79bae4f747c2e591413f5de3e9ba85b6
https://doi.org/10.1101/2020.11.13.382382
https://doi.org/10.1101/2020.11.13.382382
Autor:
Leonid L. Moroz, Dirk Fasshauer, Emilie Neveu, Frederique Varoqueaux, Daria Y. Romanova, Andrea B. Kohn, Mikhail A. Nikitin, Dosung Sohn
Publikováno v:
Scientific reports, vol. 10, no. 1, pp. 13020
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Nitric oxide (NO) is a ubiquitous gaseous messenger, but we know little about its early evolution. Here, we analyzed NO synthases (NOS) in four different species of placozoans—one of the early-branching animal lineages. In contrast to other inverte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a596aebbc5ab476316096c5380d861e2
https://serval.unil.ch/notice/serval:BIB_3BE4C833620A
https://serval.unil.ch/notice/serval:BIB_3BE4C833620A
Autor:
Ilona, Kondratiuk, Shrutee, Jakhanwal, Jialin, Jin, Udhayabhaskar, Sathyanarayanan, Benjamin, Kroppen, Ajaybabu V, Pobbati, Anita, Krisko, Uri, Ashery, Michael, Meinecke, Reinhard, Jahn, Dirk, Fasshauer, Ira, Milosevic
Publikováno v:
Proc Natl Acad Sci U S A
The functions of nervous and neuroendocrine systems rely on fast and tightly regulated release of neurotransmitters stored in secretory vesicles through SNARE-mediated exocytosis. Few proteins, including tomosyn (STXBP5) and amisyn (STXBP6), were pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf59df35f58e906c1de78af29c503431
https://pubmed.ncbi.nlm.nih.gov/32467162
https://pubmed.ncbi.nlm.nih.gov/32467162
Autor:
Andreas Heyland, Dirk Fasshauer, Daria Y. Romanova, Dosung Sohn, Andrea B. Kohn, Frederique Varoqueaux, Leonid L. Moroz
Publikováno v:
Neuroreport. 31(6)
The origin and early evolution of neurotransmitter signaling in animals are unclear due to limited comparative information, primarily about prebilaterian animals. Here, we performed the comparative survey of signal molecules in placozoans - the simpl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bb9f53a6c241f56ba647f2a01d8f289
https://pubmed.ncbi.nlm.nih.gov/32243353
https://pubmed.ncbi.nlm.nih.gov/32243353