Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Dirk Fahrenkamp"'
Autor:
Sean Miletic, Dirk Fahrenkamp, Nikolaus Goessweiner-Mohr, Jiri Wald, Maurice Pantel, Oliver Vesper, Vadim Kotov, Thomas C. Marlovits
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Virulent type III secretion systems (T3SSs) or injectisomes enable pathogenic bacteria to inject effector proteins directly into the host cell cytoplasm. Structures of a needle complex engaged with the effector protein reveal the complete secretion c
Externí odkaz:
https://doaj.org/article/66891609afd94b18bb304e7a5fff8d52
Autor:
Anna Cuppari, Hagen Körschgen, Dirk Fahrenkamp, Carlo Schmitz, Tibisay Guevara, Konstantin Karmilin, Michael Kuske, Mario Olf, Eileen Dietzel, Irene Yiallouros, Daniele de Sanctis, Theodoros Goulas, Ralf Weiskirchen, Willi Jahnen-Dechent, Julia Floehr, Walter Stoecker, Luca Jovine, F. Xavier Gomis-Rüth
Publikováno v:
IUCrJ, Vol 6, Iss 2, Pp 317-330 (2019)
Mammalian fetuin-A and fetuin-B are abundant serum proteins with pleiotropic functions. Fetuin-B is a highly selective and potent inhibitor of metallopeptidases (MPs) of the astacin family, which includes ovastacin in mammals. By inhibiting ovastacin
Externí odkaz:
https://doaj.org/article/24d7abbd57094fd4a8c4d4c291760b72
Characterization of SLCO5A1/OATP5A1, a solute carrier transport protein with non-classical function.
Autor:
Katrin Sebastian, Silvia Detro-Dassen, Natalie Rinis, Dirk Fahrenkamp, Gerhard Müller-Newen, Hans F Merk, Günther Schmalzing, Gabriele Zwadlo-Klarwasser, Jens Malte Baron
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83257 (2013)
Organic anion transporting polypeptides (OATP/SLCO) have been identified to mediate the uptake of a broad range of mainly amphipathic molecules. Human OATP5A1 was found to be expressed in the epithelium of many cancerous and non-cancerous tissues thr
Externí odkaz:
https://doaj.org/article/00d3f5fd9ad443d1a4da1802269dafaf
Autor:
Vadim Kotov, Dirk Fahrenkamp, Maurice Pantel, Nikolaus Goessweiner-Mohr, Oliver Vesper, Thomas C. Marlovits, Jiri Wald, Sean Miletic
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications 12(1), 1546 (2021). doi:10.1038/s41467-021-21143-1
Nature Communications
Nature Communications 12(1), 1546 (2021). doi:10.1038/s41467-021-21143-1
Nature Communications
Nature Communications 12(1), 1546 (2021). doi:10.1038/s41467-021-21143-1
Many bacterial pathogens rely on virulent type III secretion systems (T3SSs) or injectisomes to translocate effector proteins in order to establish infection. The central c
Many bacterial pathogens rely on virulent type III secretion systems (T3SSs) or injectisomes to translocate effector proteins in order to establish infection. The central c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c36bc9678f6413bdbdb1be802e03d6a0
https://doaj.org/article/66891609afd94b18bb304e7a5fff8d52
https://doaj.org/article/66891609afd94b18bb304e7a5fff8d52
Autor:
Jiri Wald, Dirk Fahrenkamp, Nikolaus Goessweiner-Mohr, Wolfgang Lugmayr, Luciano Ciccarelli, Oliver Vesper, Thomas C. Marlovits
Publikováno v:
Nature 609(7927), 630-639 (2022). doi:10.1038/s41586-022-05121-1
Nature 609(7927), 630 - 639 (2022). doi:10.1038/s41586-022-05121-1
The Holliday junction is a key intermediate formed during DNA recombination across all kingdoms of life1. In bacteria, the Holliday junction is processed by two homo-hexameric AA
The Holliday junction is a key intermediate formed during DNA recombination across all kingdoms of life1. In bacteria, the Holliday junction is processed by two homo-hexameric AA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::273adfbaf02a85f464556be2fa5a6799
https://pubmed.ncbi.nlm.nih.gov/36002576
https://pubmed.ncbi.nlm.nih.gov/36002576
Autor:
Jiri Wald, Edith N.G. Houben, Thomas C. Marlovits, Dirk Fahrenkamp, Roy Ummels, Catalin M. Bunduc, Wilbert Bitter
Publikováno v:
Nature
Nature, 593(7859), 445-448. Nature Publishing Group
Bunduc, C M, Fahrenkamp, D, Wald, J, Ummels, R, Bitter, W, Houben, E N G & Marlovits, T C 2021, ' Structure and dynamics of a mycobacterial type VII secretion system ', Nature, vol. 593, no. 7859, pp. 445-448 . https://doi.org/10.1038/s41586-021-03517-z
Nature 593(7859), 445-448 (2021). doi:10.1038/s41586-021-03517-z
Nature, 593(7859), 445-448. Nature Publishing Group
Bunduc, C M, Fahrenkamp, D, Wald, J, Ummels, R, Bitter, W, Houben, E N G & Marlovits, T C 2021, ' Structure and dynamics of a mycobacterial type VII secretion system ', Nature, vol. 593, no. 7859, pp. 445-448 . https://doi.org/10.1038/s41586-021-03517-z
Nature
Nature 593(7859), 445 - 448 (2021). doi:10.1038/s41586-021-03517-z
Mycobacterium tuberculosis is the cause of one of the most important infectious diseases in humans, which leads to 1.4 million deaths every year1. Specialized protein transport s
Mycobacterium tuberculosis is the cause of one of the most important infectious diseases in humans, which leads to 1.4 million deaths every year1. Specialized protein transport s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5feecedfa21ba12192adcb1dfd18ffa
https://pubmed.ncbi.nlm.nih.gov/33981042
https://pubmed.ncbi.nlm.nih.gov/33981042
Autor:
Yichen Li, Franck Duong Van Hoa, Harveer Singh Dhupar, Maria S Loos, Rinky Parakra, Anastassios Economou, Jiri Wald, Biao Yuan, Athina G. Portaliou, Spyridoula Karamanou, Thomas C. Marlovits, Charalampos G. Kalodimos, Jochem H. Smit, Thorben Cordes, Bindu Y. Srinivasu, Dirk Fahrenkamp
Publikováno v:
Journal of Molecular Biology, 433(21):167188. Academic Press
Type III protein secretion is widespread in Gram-negative pathogens. It comprises the injectisome with a surface-exposed needle and an inner membrane translocase. The translocase contains the SctRSTU export channel enveloped by the export gate subuni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46dfc0ddfb25c0459e108c0fa14fb9b9
https://doi.org/10.1016/j.jmb.2021.167188
https://doi.org/10.1016/j.jmb.2021.167188
Autor:
Ulrich Simon, Gerhard Müller-Newen, Julia Steitz, Dirk Fahrenkamp, Felix M. Mottaghy, Andreas T. J. Vogg, Stefan Westhues, Janine Broda, Andrea Küster
Publikováno v:
Advanced Healthcare Materials, 5(24), 3118-3128. Wiley
As the size of nanoparticles (NPs) is in the range of biological molecules and subcellular structures, they provide new perspectives in biomedicine. This work presents studies concerning the cellular uptake and distribution of phosphine-stabilized cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f541306dde022ad1053d56c235b0da95
https://cris.maastrichtuniversity.nl/en/publications/12c9d62e-71cc-4007-b0fd-dd290ed2dc54
https://cris.maastrichtuniversity.nl/en/publications/12c9d62e-71cc-4007-b0fd-dd290ed2dc54
Publikováno v:
Leukemia. 31:1017-1019
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d021f7ede4a48fa684f94a7037ea58af
https://doi.org/10.1038/leu.2017.19
https://doi.org/10.1038/leu.2017.19
Autor:
Ute Haas, Fabio Ticconi, D Lambertz, Wei Hu, Ivan G. Costa, Mariano Barbacid, Nikolaus Gassler, R Sonntag, Christian Trautwein, Nives Giebeler, Yulia A. Nevzorova, Francisco Javier Cubero, Christian Liedtke, Ali T. Abdallah, JM Bangen, Dirk Fahrenkamp, Ralf Weiskirchen, Gerhard Müller-Newen
E-type cyclins E1 (CcnE1) and E2 (CcnE2) are regulatory subunits of cyclin-dependent kinase 2 (Cdk2) and thought to control the transition of quiescent cells into the cell cycle. Initial findings indicated that CcnE1 and CcnE2 have largely overlappin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d856a88482cea2bf897712968da47bb
https://europepmc.org/articles/PMC6140539/
https://europepmc.org/articles/PMC6140539/
