Zobrazeno 1 - 10
of 167
pro vyhledávání: '"Dirk F. Moore"'
Autor:
Stephanie H. Greco, MD, David A. August, MD, Mihir M. Shah, MD, Chunxia Chen, MS, Dirk F. Moore, PhD, Monika Masanam, BA, Amber L. Turner, MPH, Salma K. Jabbour, MD, Parisa Javidian, MD, Miral S. Grandhi, MD, Timothy J. Kennedy, MD, H. Richard Alexander, MD, Darren R. Carpizo, MD, PhD, Russell C. Langan, MD
Publikováno v:
Surgery Open Science, Vol 3, Iss , Pp 22-28 (2021)
Background: Neoadjuvant therapy (NAT) for T1/T2 pancreatic adenocarcinoma (PDAC) prior to pancreaticoduodenectomy remains controversial. We compared positive margin rates in patients with clinical T1&T2 tumors who did and did not receive NAT. Methods
Externí odkaz:
https://doaj.org/article/5bf9b49f411748fd876da8ad503e6596
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
The protein arginine methyl transferase PRMT5 is an enzyme expressed in oligodendrocyte lineage cells and responsible for the symmetric methylation of arginine residues on histone tails. Previous work from our laboratory identified PRMT5 as critical
Externí odkaz:
https://doaj.org/article/a1183bdfe91e4e6c936cd6f809c381de
Autor:
Jennifer A. Wiseman, Yu Meng, Yuliya Nemtsova, Paul G. Matteson, James H. Millonig, Dirk F. Moore, David E. Sleat, Peter Lobel
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 4, Iss C, Pp 204-212 (2017)
Late infantile neuronal ceroid lipofuscinosis (LINCL) is a fatal inherited neurodegenerative disease caused by loss of lysosomal protease tripeptidyl peptidase 1 (TPP1). We have investigated the effects of chronic intrathecal (IT) administration usin
Externí odkaz:
https://doaj.org/article/5378431c719449ffbe5c0dc427cf4ba0
Autor:
Salma K. Jabbour, Shyamal Patel, Joseph M. Herman, Aaron Wild, Suneel N. Nagda, Taghrid Altoos, Ahmet Tunceroglu, Nilofer Azad, Susan Gearheart, Rebecca A. Moss, Elizabeth Poplin, Lydia L. Levinson, Ravi A. Chandra, Dirk F. Moore, Chunxia Chen, Bruce G. Haffty, Richard Tuli
Publikováno v:
International Journal of Surgical Oncology, Vol 2012 (2012)
Purpose. To compare the acute toxicities of IMRT to 3D-conformal radiation therapy (3DCRT) in the treatment of rectal cancer. Methods and Materials. Eighty-six patients with rectal cancer preoperatively treated with IMRT (n=30) and 3DCRT (n=56) were
Externí odkaz:
https://doaj.org/article/9b066ea233cd4b21807fc6aa900225d6
Autor:
Victor P. Gazivoda, Aaron W. Kangas-Dick, Alissa A. Greenbaum, Joshua Roshal, Chunxia Chen, Dirk F. Moore, Russell C. Langan, Timothy J. Kennedy, Christine Minerowicz, H. Richard Alexander
Publikováno v:
Journal of Surgical Research. 277:131-137
Frequency of PD-L1 expression and the role of immunotherapy in malignant peritoneal mesothelioma (MPM) have not been well characterized. The purpose of this study was to determine PD-L1 expression in patients with MPM and perform an exploratory analy
Publikováno v:
Journal of Proteome Research. 21:1371-1381
Knowledge of cellular location is key to understanding the biological function of proteins. One commonly used large-scale method to assign cellular locations is subcellular fractionation, followed by quantitative mass spectrometry to identify protein
Autor:
S. Balasubramanian, Nikhil Yegya-Raman, Salma K. Jabbour, Jyoti Malhotra, Shang-Jui Wang, Matthew P. Deek, Joseph Aisner, Parima Daroui, Malini Patel, Dirk F. Moore
Publikováno v:
Annals of Palliative Medicine. 10:7205-7213
BACKGROUND Locally advanced non-small cell lung cancer (NSCLC) is typically treated with concurrent chemoradiation (CRT). Excision Repair Cross-Complementing 1 (ERCC1) is a protein involved in DNA damage repair. The objective of this study was to ass
Autor:
Kristen Renee Spencer, Howard S. Hochster, Patrick M Boland, Lyudmyla Derby Berim, Timothy Kennedy, Miral Grandhi, Russell C Langan, Dirk F. Moore, Michael P. Kane, Smitha S. Krishnamurthi, Skye C. Mayo, Anup Kasi, Agustin Pimentel, Darren R. Carpizo
Publikováno v:
Journal of Clinical Oncology. 41:103-103
103 Background: Novel strategies to improve the efficacy of immune checkpoint inhibitors in microsatellite stable (MSS) mCRC are needed. CV301 is a vector-based vaccine that expresses carcinoembryonic antigen (CEA) and mucin 1 (MUC1), and in a phase
Autor:
Salma K. Jabbour, Miral S. Grandhi, H. Richard Alexander, Darren R. Carpizo, Amber L. Turner, Timothy J. Kennedy, Chunxia Chen, Russell C. Langan, David A. August, Stephanie H. Greco, Monika Masanam, Dirk F. Moore, Parisa Javidian, Mihir M. Shah
Publikováno v:
Surgery Open Science
Surgery Open Science, Vol 3, Iss, Pp 22-28 (2021)
Surgery Open Science, Vol 3, Iss, Pp 22-28 (2021)
Background Neoadjuvant therapy (NAT) for T1/T2 pancreatic adenocarcinoma (PDAC) prior to pancreaticoduodenectomy remains controversial. We compared positive margin rates in patients with clinical T1&T2 tumors who did and did not receive NAT. Methods
Autor:
Gratian Salaru, Elan Gorshein, Kevin A. David, Dirk F. Moore, Weichung Shih, Rebecca Krakora, Chunxia Chen, Pallvi Popli, Rajat Bannerji
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 20:e890-e896
Background Socioeconomic factors including race, ethnicity, and poverty level have been associated with disparities in survival among adult patients with acute leukemia. Insurance status is also likely to affect survival outcomes in these patients bu