Výsledky vyhledávání - "Dirk C. Davidson"

Abstract P3-06-28: Use of the MiCK drug-induced apoptosis assay improves clinical outcomes in recurrent breast cancer (BRCA)

Autor: Misagh Karimi, Karl Rogers, Cary A. Presant, Allan Hallquist, Linda D. Bosserman, Mathieu Perree, James Rutledge, G. Upadhyaya, P. W. Whitworth, Dirk C. Davidson

Publikováno v: Cancer Research. 72:P3-06

Background: The microculture kinetic (MiCK) assay (Correct Chemo™) correlates with outcomes in acute myelocytic leukemia and ovarian cancer (Cancer Research, in press). A prior trial suggested that its use in breast cancer could improve clinical ou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e0a5354496413ec499b6f37ae87f6a0b
https://doi.org/10.1158/0008-5472.sabcs12-p3-06-28

Zobrazit plný text záznamu

The Microculture-Kinetic (MiCK) Assay: The Role of a Drug-Induced Apoptosis Assay in Drug Development and Clinical Care

Publikováno v: Cancer Research. 72:3901-3905

A drug-induced apoptosis assay, termed the microculture-kinetic (MiCK) assay, has been developed. Blinded clinical trials have shown higher response rates and longer survival in groups of patients with acute myelocytic leukemia and epithelial ovarian

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c83d4df2d6d01f0b83cd128ca31c2fc5
https://doi.org/10.1158/0008-5472.can-12-0681

Zobrazit plný text záznamu

Correlation of drug-induced apoptosis assay results with oncologist treatment decisions and patient response and survival

Autor: Swapnil Rajurkar, Allan Hallquist, Dirk C. Davidson, Karl Rogers, Debbee Malouf, Cary A. Presant, Linda D. Bosserman, Michael R. Chernick

Publikováno v: Cancer. 118:4877-4883

BACKGROUND: An observational prospective nonblinded clinical trial was performed to determine the effect of a drug-induced apoptosis assay results on treatments planned by oncologists. METHODS: Purified cancer cells from patient biopsies were placed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc405bb31f253568fe27b8970ea0a0e3
https://doi.org/10.1002/cncr.27444

Zobrazit plný text záznamu

PersonalizedCancer Care: A New Paradigm in Oncology

Autor: Emery M. Salom, Allan Hallquist, Karl Rogers, Swapnil Rajurkar, Dirk C. Davidson, Pat Whitworth, Cary A. Presant

Publikováno v: Oncology Issues. 25:18-23

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c9683ddcaf6a81d5693601fe7f28a7fb
https://doi.org/10.1080/10463356.2010.11883494

Zobrazit plný text záznamu

Application of a Drug-Induced Apoptosis Assay to Identify Treatment Strategies in Recurrent or Metastatic Breast Cancer

Autor: Linda D. Bosserman, Mathieu Perree, Carl Rogaston Willis, Cary A. Presant, James Rutledge, Misagh Karimi, Allan Hallquist, Pat Whitworth, Karl Rogers, G. Upadhyaya, Dirk C. Davidson

Publikováno v: PLoS ONE
PLoS ONE, Vol 10, Iss 5, p e0122609 (2015)

Background A drug-induced apoptosis assay has been developed to determine which chemotherapy drugs or regimens can produce higher cell killing in vitro. This study was done to determine if this assay could be performed in patients with recurrent or m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb63e91e0381161b7cd437205bd5ae4
http://europepmc.org/articles/PMC4449169

Zobrazit plný text záznamu

Are generic multisource (generic) chemotherapy (CT) drugs as effective as proprietary single-source (proprietary) drugs: Evidence from in vitro CT-induced apoptosis (APOP) in non-small cell lung cancer (NSCLC), colorectal cancer (Colon CA) compared to recurrent/metastatic breast carcinoma (Breast CA)

Autor: Dirk C. Davidson, Linda D. Bosserman, Cary A. Presant, Misagh Karimi, Karl Rogers, James Rutledge, Swapnil Rajurkar, Allan Hallquist, Carl Rogaston Willis

Publikováno v: Journal of Clinical Oncology. 30:e13003-e13003

e13003 Background: We have demonstrated that cancer cells from patients (Pts) with recurrent or metastatic Breast CA frequently show as much or better APOP with Generics compared to Proprietaries (separately submitted to ASCO, 2012). We have compared

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fca55b36878b6d28b79da2dfc8b3f6dc
https://doi.org/10.1200/jco.2012.30.15_suppl.e13003

Zobrazit plný text záznamu

Patterns of in vitro chemotherapy (CT)-induced apoptosis (APOP) in recurrent/metastatic breast carcinoma (CA): Comparisons of generic multisource drugs (generics) with proprietary single-source drugs (proprietaries)

Autor: Dirk C. Davidson, Karl Rogers, Cary A. Presant, Linda D. Bosserman, James Rutledge, Allan Hallquist, Carl Rogaston Willis, Tracy Young, Swapnil Rajurkar, Misagh Karimi

Publikováno v: Journal of Clinical Oncology. 30:e11562-e11562

e11562 Background: Therapy of metastatic breast CA involves choices between Generics and Proprietaries, and between combination CTs (Combos) and single-agent CTs. This study determined the relative in vitro CT induced APOP of Generics versus Propriet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cab332a6fb16136fa1dce8881f80aec0
https://doi.org/10.1200/jco.2012.30.15_suppl.e11562

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání