Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Dirk Bartnik"'
Autor:
Antonia Nicole Klein, Tamar Ziehm, Markus Tusche, Johan Buitenhuis, Dirk Bartnik, Annett Boeddrich, Thomas Wiglenda, Erich Wanker, Susanne Aileen Funke, Oleksandr Brener, Lothar Gremer, Janine Kutzsche, Dieter Willbold
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153035 (2016)
The aggregation of amyloid-β (Aβ) is postulated to be the crucial event in Alzheimer's disease (AD). In particular, small neurotoxic Aβ oligomers are considered to be responsible for the development and progression of AD. Therefore, elimination of
Externí odkaz:
https://doaj.org/article/083680e70c82443787f8e0d46841487d
Autor:
Susanne Aileen Funke, Dirk Bartnik, Julian Marius Glück, Kasia Piorkowska, Katja Wiesehan, Urs Weber, Balazs Gulyas, Christer Halldin, Andrea Pfeifer, Christian Spenger, Andreas Muhs, Dieter Willbold
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41457 (2012)
Alzheimer's disease (AD) is a devastating disease affecting predominantly the aging population. One of the characteristic pathological hallmarks of AD are neuritic plaques, consisting of amyloid-β peptide (Aβ). While there has been some advancement
Externí odkaz:
https://doaj.org/article/ce9a1aae78d8452baa52b21d0c56408f
Autor:
Christian Lévêque, Jacques Fantini, Dirk Bartnik, Mariarosa A. B. Melone, Honoree Mazargui, Tiphany Gouget, Dieter Willbold, Susanne Aileen Funke, Lorena Perrone
Publikováno v:
Aging Cell. 11:530-541
Alzheimer's disease (AD) is the most common cause of dementia in elderly people, and age is the major nongenetic risk factor for sporadic AD. A hallmark of AD is the accumulation of amyloid in the brain, which is composed mainly of the amyloid beta-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42aaf681e75bf2449728c0fa82e4eedd
https://doi.org/10.1111/j.1474-9726.2012.00814.x
https://doi.org/10.1111/j.1474-9726.2012.00814.x
Autor:
Anselm H. C. Horn, Marco Hellmert, Dirk Bartnik, Jolanta Polkowska, Christine Moriscot, Julia März-Berberich, Dieter Willbold, Guy Schoehn, Heinrich Sticht, Andreas Müller-Schiffmann, Aksana Andreyeva, S. Aileen Funke, Oleksandr Brener, Kurt Gottmann, Janine Kutzsche, Carsten Korth, Thomas Schrader, Luitgart Nagel-Steger, Raik Rönicke, Klaus G. Reymann
Publikováno v:
Angewandte Chemie. 122:8925-8928
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5f2391eca69e40cb7b54ec42eefdd8f
https://doi.org/10.1002/ange.201004437
https://doi.org/10.1002/ange.201004437
Autor:
Dirk Bartnik, Luitgard Nagel-Steger, Andreas Müller-Schiffmann, Carsten Korth, Renu Batra-Safferling, Inga Kadish, Torsten Sehl, Christine Moriscot, Oleksandr Brener, Thomas van Groen, Heinrich Sticht, Dieter Willbold, Guy Schoehn, Susanne Aileen Funke, Anselm H. C. Horn
Publikováno v:
ACS Chemical Neuroscience. 1:639-648
Several lines of evidence suggest that the amyloid-β-peptide (Aβ) plays a central role in the pathogenesis of Alzheimer's disease (AD). Not only Aβ fibrils but also small soluble Aβ oligomers in particular are suspected to be the major toxic spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60cfa9582d6a69b371e82d2ae2a3b14d
https://doi.org/10.1021/cn100057j
https://doi.org/10.1021/cn100057j
Autor:
Dirk Bartnik, Antonia Nicole Klein, Christine Schlosser, Markus Tusche, Dieter Willbold, Janine Kutzsche
Publikováno v:
Alzheimer's & Dementia. 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::699caaef8eda633f80ad37d5e076f63e
https://doi.org/10.1016/j.jalz.2014.05.668
https://doi.org/10.1016/j.jalz.2014.05.668
Publikováno v:
Alzheimer disease & associated disorders 34(3), 609-620 (2013). doi:10.3233/JAD-121792
One of the characteristic pathological hallmarks of Alzheimer's disease (AD) is neuritic plaques. The sequence of events leading to deposition of amyloid-β (Aβ) peptides in plaques is not clear. Here we investigate the effects of D3, an Aβ oligome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96968dcfab843a4cb79e7babe41b25c1
https://juser.fz-juelich.de/record/133637
https://juser.fz-juelich.de/record/133637
Publikováno v:
Advances in protein chemistry and structural biology. 88
One of the two characteristic pathological hallmarks of Alzheimer's disease (AD) are neuritic plaques. The sequence of events leading to the extracellular deposition of amyloid β (Aβ) peptides in plaques or in diffuse deposits is not clear. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f5b10598756b873872bd7cfd1ec33883
https://pubmed.ncbi.nlm.nih.gov/22814708
https://pubmed.ncbi.nlm.nih.gov/22814708
Autor:
Honoree, Mazargui, Christian, Lévêque, Dirk, Bartnik, Jacques, Fantini, Tiphany, Gouget, Mariarosa A B, Melone, Susanne A, Funke, Dieter, Willbold, Lorena, Perrone
Alzheimer's disease (AD) is the most common cause of dementia in elderly people, and age is the major nongenetic risk factor for sporadic AD. A hallmark of AD is the accumulation of amyloid in the brain, which is composed mainly of the amyloid beta-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5f160da10d87f433edf237a2e7452987
http://hdl.handle.net/11591/236150
http://hdl.handle.net/11591/236150
One of the two characteristic pathological hallmarks of Alzheimer's disease (AD) are neuritic plaques. The sequence of events leading to the extracellular deposition of amyloid β (Aβ) peptides in plaques or in diffuse deposits is not clear. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8178374a1e9a9db1ed7c96b5c374e74d
https://doi.org/10.1016/b978-0-12-398314-5.00005-2
https://doi.org/10.1016/b978-0-12-398314-5.00005-2