Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Dirk A. Darnell"'
Autor:
Cedar J. Fowler, Ian N. Moore, Alexandra F. Freeman, Dirk A. Darnell, Mary Garofalo, Mark D. Kieh, Steven M. Holland, Pamela Welch, Arian Laurence, Sundar Ganesan, Portia Gough, John I. Gallin, Kelli W. Williams, Erik D. Anderson, Noah J. Earland, Arhum Saleem, Sandip K. Datta, Ian A. Myles, Inka Sastalla, Kol A. Zarember, Douglas B. Kuhns
Publikováno v:
Journal of Clinical Investigation. 128:3595-3604
Autosomal dominant hyper IgE syndrome (AD-HIES), or Job's syndrome, is a primary immune deficiency caused by dominant-negative mutations in STAT3. Recurrent Staphylococcus aureus skin abscesses are a defining feature of this syndrome. A widely held h
Autor:
Mark D. Kieh, Noah J. Earland, Arhum Saleem, Ian A. Myles, Ashleigh A. Sun, Ian N. Moore, Lisa A. Barnhart, Gulbu Uzel, Kelli W. Williams, Dirk A. Darnell, Sandip K. Datta, Natalia M. Fontecilla, Erik D. Anderson, Pamela Welch
Publikováno v:
JCI insight. 3(9)
The underlying pathology of atopic dermatitis (AD) includes impaired skin barrier function, susceptibility to Staphylococcus aureus skin infection, immune dysregulation, and cutaneous dysbiosis. Our recent investigation into the potential role of Gra