Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Dirk, Loeffler"'
Autor:
Geethika Arekatla, Stavroula Skylaki, David Corredor Suarez, Hartland Jackson, Denis Schapiro, Stefanie Engler, Markus Auler, German Camargo Ortega, Simon Hastreiter, Andreas Reimann, Dirk Loeffler, Bernd Bodenmiller, Timm Schroeder
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Pluripotent mouse embryonic stem cells (ESCs) can differentiate to all germ layers and serve as an in vitro model of embryonic development. To better understand the differentiation paths traversed by ESCs committing to different lineages, we
Externí odkaz:
https://doaj.org/article/b8a1252720554a2e99b83d10ecd90a0e
Autor:
Lars Duester, Vera Breitung, Marvin Brinke, Sebastian Buchinger, Georg Dierkes, Christian Dietrich, Jens Hahn, Kevin S. Jewell, Carmen Kleisinger, Dirk Loeffler, Dirk Radny, Georg Reifferscheid, Sabine Schäfer, Michael P. Schluesener, Axel Schmidt, Daniel Schwandt, Andreas Schüttler, Matthias Stoffels, Rike Voelpel, Arne Wick, Jan G. Wiederhold, Alexander Zavarsky, Thomas A. Ternes
Publikováno v:
Environmental Sciences Europe, Vol 36, Iss 1, Pp 1-19 (2024)
Abstract With the nationwide introduction of wastewater treatment the overall water quality improved significantly, but challenges remain, including diffuse pollution, historical sediment contamination and the presence of a multitude of anthropogenic
Externí odkaz:
https://doaj.org/article/3aa5c67b55af4123af89674e3131e4b7
Autor:
Jessica Nunes, Dirk Loeffler
Publikováno v:
Frontiers in Hematology, Vol 3 (2024)
Hematopoietic stem cells (HSCs) can self-renew and differentiate for the entire life of an organism to produce new blood cells when needed. This process is regulated by asymmetric cell division (ACD), an evolutionarily conserved mechanism whereby cel
Externí odkaz:
https://doaj.org/article/56a2fe43637541bb8e121c222fd28671
Autor:
Dirk Loeffler
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/3c0131a089504a33b5bf0925a6dc64d7
Autor:
Philip Dettinger, Tobias Kull, Geethika Arekatla, Nouraiz Ahmed, Yang Zhang, Florin Schneiter, Arne Wehling, Daniel Schirmacher, Shunsuke Kawamura, Dirk Loeffler, Timm Schroeder
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Liquid handling and pipetting tools can automate repetitive tasks but are far from universally used. Here the authors report the Pipetting Helper Imaging Lid (PHIL), an open-source liquid handling robot designed for inexperienced users, that they use
Externí odkaz:
https://doaj.org/article/de59854a8b844e02bd342bc84f670d0b
Autor:
Michael K. Strasser, Philipp S. Hoppe, Dirk Loeffler, Konstantinos D. Kokkaliaris, Timm Schroeder, Fabian J. Theis, Carsten Marr
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
The timing of cell fate choices is usually unknown, because we have to rely on indirect evidence of their molecular basis. Here, the authors introduce a method to infer decision times from marker onset in cell genealogies, and find evidence refuting
Externí odkaz:
https://doaj.org/article/983bff561cd148d39c9c6755fd3f3b03
Autor:
Simon Hastreiter, Stavroula Skylaki, Dirk Loeffler, Andreas Reimann, Oliver Hilsenbeck, Philipp S. Hoppe, Daniel L. Coutu, Konstantinos D. Kokkaliaris, Michael Schwarzfischer, Konstantinos Anastassiadis, Fabian J. Theis, Timm Schroeder
Publikováno v:
Stem Cell Reports, Vol 11, Iss 1, Pp 58-69 (2018)
Summary: Embryonic stem cells (ESCs) display heterogeneous expression of pluripotency factors such as Nanog when cultured with serum and leukemia inhibitory factor (LIF). In contrast, dual inhibition of the signaling kinases GSK3 and MEK (2i) convert
Externí odkaz:
https://doaj.org/article/9562e4e013e74333b15588cca58c4372
Autor:
Geethika Arekatla, Christoph Trenzinger, Andreas Reimann, Dirk Loeffler, Tobias Kull, Timm Schroeder
Publikováno v:
Developmental Cell.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59f99b8af86acf1bda3bdb82efbe393a
https://doi.org/10.1016/j.devcel.2023.04.013
https://doi.org/10.1016/j.devcel.2023.04.013
Autor:
Markus G. Manz, Dirk Loeffler, Arne Wehling, Florin Schneiter, Tobias Kull, Claudia Lengerke, Timm Schroeder, Weijia Wang
Publikováno v:
Blood, 139 (13)
Blood
Blood
Understanding human hematopoietic stem cell fate control is important for its improved therapeutic manipulation. Asymmetric cell division, the asymmetric inheritance of factors during division instructing future daughter cell fates, was recently desc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a1a325712e61d900f98435e570e4c15
https://doi.org/10.1182/blood.2020009778
https://doi.org/10.1182/blood.2020009778
Publikováno v:
Stem Cell Reports, 18 (6)
Signaling is central in cell fate regulation, and relevant information is encoded in its activity over time (i.e., dynamics). However, simultaneous dynamics quantification of several pathways in single mammalian stem cells has not yet been accomplish
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f005eb02e56cb09ecea12c1b1990586
