Zobrazeno 1 - 10
of 346
pro vyhledávání: '"Direct RNA sequencing"'
Autor:
Adriano Fonzino, Caterina Manzari, Paola Spadavecchia, Uday Munagala, Serena Torrini, Silvestro Conticello, Graziano Pesole, Ernesto Picardi
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 113-126 (2024)
In mammals, RNA editing events involve the conversion of adenosine (A) in inosine (I) by ADAR enzymes or the hydrolytic deamination of cytosine (C) in uracil (U) by the APOBEC family of enzymes, mostly APOBEC1. RNA editing has a plethora of biologica
Externí odkaz:
https://doaj.org/article/207157cd5c65498fbb0bdc42d0621b38
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 560-574 (2024)
2´-O-methylation (Nm) is one of the most abundant modifications found in both mRNAs and noncoding RNAs. It contributes to many biological processes, such as the normal functioning of tRNA, the protection of mRNA against degradation by the decapping
Externí odkaz:
https://doaj.org/article/b4116d68eda54be283e2902fcc05a789
Autor:
Wang Liu-Wei, Wiep van der Toorn, Patrick Bohn, Martin Hölzer, Redmond P. Smyth, Max von Kleist
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-15 (2024)
Abstract Background Direct RNA sequencing (dRNA-seq) on the Oxford Nanopore Technologies (ONT) platforms can produce reads covering up to full-length gene transcripts, while containing decipherable information about RNA base modifications and poly-A
Externí odkaz:
https://doaj.org/article/cd3c7d0cec67474b96de101bc58c8145
Autor:
Milenkovic, Ivan 1, 2, Cruciani, Sonia 1, 2, Llovera, Laia 1, Lucas, Morghan C. 1, 2, Medina, Rebeca 1, Pauli, Cornelius 3, 4, 5, Heid, Daniel 3, 4, 5, Muley, Thomas 6, 7, Schneider, Marc A. 6, 7, Klotz, Laura V. 8, Allgäuer, Michael 9, Lattuca, Ruben 10, Lafontaine, Denis L.J. 10, Müller-Tidow, Carsten 3, 4, Novoa, Eva Maria 1, 2, 11, 12, ∗
Publikováno v:
In Molecular Cell 2 January 2025 85(1):177-190
Autor:
Weizhen Li, Yong Huang, Haowen Yuan, Jingwan Han, Zhengyang Li, Aiping Tong, Yating Li, Hanping Li, Yongjian Liu, Lei Jia, Xiaolin Wang, Jingyun Li, Bohan Zhang, Lin Li
Publikováno v:
Heliyon, Vol 10, Iss 20, Pp e39474- (2024)
Post-transcriptional processing and modification of viral RNA, including alternative splicing, polyadenylation, and methylation, play crucial roles in regulating viral gene expression, enhancing genomic stability, and increasing replication efficienc
Externí odkaz:
https://doaj.org/article/5f57640b9ef041e3bbeff8aeeb69ba8f
Autor:
Jundong Rong, Yushan Zheng, Zeyu Zhang, Jun Zhang, Yuying Gu, Tian Hua, Mengna Zhao, Lili Fan, Zhiwen Deng, Yanmei Pan, Bingjun Li, Liguang Chen, Tianyou He, Lingyan Chen, Jing Ye, Hangxiao Zhang, Lianfeng Gu
Publikováno v:
Advanced Science, Vol 11, Iss 40, Pp n/a-n/a (2024)
Abstract Fokienia hodginsii (F. hodginsii), belonging to the genus Fokienia of the Cupressaceae. F. hodginsii has significant application value due to its wood properties and great research value in evolutionary studies as a gymnosperm. However, the
Externí odkaz:
https://doaj.org/article/dcce1ff3b7e7479cb2af10b209f07506
Autor:
John S. A. Mattick, Robin E. Bromley, Kaylee J. Watson, Ricky S. Adkins, Christopher I. Holt, Jarrett F. Lebov, Benjamin C. Sparklin, Tyonna S. Tyson, David A. Rasko, Julie C. Dunning Hotopp
Publikováno v:
mBio, Vol 15, Iss 10 (2024)
ABSTRACT RNA transcripts are potential therapeutic targets, yet bacterial transcripts have uncharacterized biodiversity. We developed an algorithm for transcript prediction called tp.py using it to predict transcripts (mRNA and other RNAs) in Escheri
Externí odkaz:
https://doaj.org/article/d0edc818c52849dfb46e0614f9812657
Publikováno v:
In Journal of Virological Methods April 2025 333
Publikováno v:
In Aquaculture 15 March 2025 598
Autor:
Jonathan S. Abebe, Yasmine Alwie, Erik Fuhrmann, Jonas Leins, Julia Mai, Ruth Verstraten, Sabrina Schreiner, Angus C. Wilson, Daniel P. Depledge
Publikováno v:
mSystems, Vol 9, Iss 7 (2024)
ABSTRACT Nanopore direct RNA sequencing (DRS) enables the capture and full-length sequencing of native RNAs, without recoding or amplification bias. Resulting data sets may be interrogated to define the identity and location of chemically modified ri
Externí odkaz:
https://doaj.org/article/6e0769599e5e491b9ab29a7c043b7473