Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Diran, Herebian"'
Autor:
Friedrich Reusswig, Maria Reich, Leonard Wienands, Diran Herebian, Verena Keitel-Anselmino, Margitta Elvers
Publikováno v:
Platelets, Vol 35, Iss 1 (2024)
AbstractLiver failure and cirrhosis are characterized by abnormal hemostasis with aberrant platelet activation. In particular, the consequences of cholestatic liver disease and molecular mechanisms, including the role of bile acids leading to impaire
Externí odkaz:
https://doaj.org/article/bd0012fe927e40debefd73b999196fd8
Autor:
Wilfred Aniagyei, Sumaya Mohayideen, Osei Sarfo-Kantanka, Sarah Bittner, Monika M. Vivekanandan, Joseph F. Arthur, Agnes O. Boateng, Augustine Yeboah, Hubert S. Ahor, Shadrack O. Asibey, Elizabeth Owusu, Diran Herebian, Maximilian Huttasch, Volker Burkart, Robert Wagner, Michael Roden, Ernest Adankwah, Dorcas O. Owusu, Ertan Mayatepek, Marc Jacobsen, Richard O. Phillips, Julia Seyfarth
Publikováno v:
Vaccines, Vol 12, Iss 5, p 452 (2024)
BCG vaccination affects other diseases beyond tuberculosis by unknown—potentially immunomodulatory—mechanisms. Recent studies have shown that BCG vaccination administered during overt type 1 diabetes (T1D) improved glycemic control and affected i
Externí odkaz:
https://doaj.org/article/40196ef4ba7349c7ace2c6867222d7a7
Autor:
Okka Scholz, Elena Huß, Silke Otter, Diran Herebian, Anna Hamacher, Laura Mariana Levy, Stanimira Hristeva, Miguel Sanz, Haresh Ajani, Alfredo Rodriguez Puentes, Torsten Hoffmann, Jens Hogeback, Anke Unger, Susanne Terheyden, Michelle Reina do Fundo, Bedair Dewidar, Michael Roden, Eckhard Lammert
Publikováno v:
Molecular Metabolism, Vol 75, Iss , Pp 101775- (2023)
Objective: Dextromethorphan (DXM) is a commonly used antitussive medication with positive effects in people with type 2 diabetes mellitus, since it increases glucose tolerance and protects pancreatic islets from cell death. However, its use as an ant
Externí odkaz:
https://doaj.org/article/79f80d669fc64506a41eecd5d5b72d9b
Autor:
Jan Stindt, Carola Dröge, Elke Lainka, Simone Kathemann, Eva-Doreen Pfister, Ulrich Baumann, Amelie Stalke, Enke Grabhorn, Mohammad Ali Shagrani, Yael Mozer-Glassberg, Jane Hartley, Marianne Wammers, Caroline Klindt, Paulina Philippski, Roman Liebe, Diran Herebian, Ertan Mayatepek, Thomas Berg, Anjona Schmidt-Choudhury, Constanze Wiek, Helmut Hanenberg, Tom Luedde, Verena Keitel
Publikováno v:
JHEP Reports, Vol 5, Iss 7, Pp 100690- (2023)
Background & Aims: Antibody-induced bile salt export pump deficiency (AIBD) is an acquired form of intrahepatic cholestasis, which may develop following orthotopic liver transplantation (OLT) for progressive familial intrahepatic cholestasis type 2 (
Externí odkaz:
https://doaj.org/article/e0f0ced14a1a400c90fd20022215385d
Autor:
Angela Pelligra, Jessica Mrugala, Kerstin Griess, Philip Kirschner, Oliver Nortmann, Barbara Bartosinska, Andrea Köster, Natalia I. Krupenko, Dominik Gebel, Philipp Westhoff, Bodo Steckel, Daniel Eberhard, Diran Herebian, Bengt-Frederik Belgardt, Jürgen Schrader, Andreas P.M. Weber, Sergey A. Krupenko, Eckhard Lammert
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112703- (2023)
Externí odkaz:
https://doaj.org/article/e559785c47a14853b575dc202e1b53de
Autor:
Haifeng C. Xu, Jun Huang, Aleksandra A. Pandyra, Piyush Pandey, Ruifeng Wang, Zeli Zhang, Yuan Zhuang, Christoph G.W. Gertzen, Carsten Münk, Diran Herebian, Arndt Borkhardt, Mike Recher, Holger Gohlke, Irene Esposito, Martin Oberbarnscheidt, Dieter Häussinger, Karl S. Lang, Philipp A. Lang
Publikováno v:
Hepatology Communications, Vol 6, Iss 7, Pp 1620-1633 (2022)
Major histocompatibility complex I (MHC‐I) molecules present epitopes on the cellular surface of antigen‐presenting cells to prime cytotoxic clusters of differentiation 8 (CD8)+ T cells (CTLs), which then identify and eliminate other cells such a
Externí odkaz:
https://doaj.org/article/162c721aae254ca7b08f8550afa6f30a
Autor:
Suchira Gallage, Adnan Ali, Jose Efren Barragan Avila, Diran Herebian, Mohammad M. Karimi, Elaine E. Irvine, Domhnall McHugh, Anne T. Schneider, Mihael Vucur, Verena Keitel, Jesús Gil, Dominic J. Withers, Tom Luedde, Mathias Heikenwalder
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 875-878 (2022)
Externí odkaz:
https://doaj.org/article/e280f4386f824a5c900ac7be2676e8ec
Autor:
Nora Helmrich, Martin Roderfeld, Anne Baier, Anita Windhorst, Diran Herebian, Ertan Mayatepek, Christian Dierkes, Matthias Ocker, Dieter Glebe, Bruno Christ, Yuri Churin, Karuna Irungbam, Elke Roeb
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 4, Pp 1041-1055 (2022)
Background & Aims: The endocannabinoid system is involved in the modulation of inflammatory, fibrotic, metabolic, and carcinogenesis-associated signaling pathways via cannabinoid receptor (CB)1 and CB2. We hypothesized that the pharmacologic antagoni
Externí odkaz:
https://doaj.org/article/d09d8c8611ec48a3bb15ab6b0b480739
Autor:
Hilde Laeremans, Charles Turner, Tommy Andersson, Jose Angel Cocho deJuan, Adam Gerrard, M. Rebecca Heiner‐Fokkema, Diran Herebian, Nils Janzen, Giancarlo laMarca, Mattias Rudebeck
Publikováno v:
JIMD Reports, Vol 53, Iss 1, Pp 90-102 (2020)
Abstract Background Nitisinone is used to treat hereditary tyrosinemia type 1 (HT‐1) by preventing accumulation of toxic metabolites, including succinylacetone (SA). Accurate quantification of SA during newborn screening is essential, as is quantif
Externí odkaz:
https://doaj.org/article/6009c65edbbf49f4820c0f103370be32
Autor:
Puyan Rafii, Friedrich Reusswig, Julia Werner, Haifeng Xu, Philpp A. Lang, Stefan Rose-John, Simone Gorressen, Christina Alter, Jürgen Schrader, Diran Herebian, Doreen M. Floss, Margitta Elvers, Roland P. Piekorz, Jürgen Scheller, Kristina Behnke
Publikováno v:
The Journal of Immunology. 210:1641-1652
IL-6 family members contribute to host defense through the stimulation of acute-phase signaling, hematopoiesis, immune reactions, and regenerative processes. To investigate essential mechanisms that are linked toward a constitutively activated gp130