Human β-Defensin 1 and β-Defensin 3 (Mouse Ortholog mBD14) Function as Full Endogenous Agonists at Select Melanocortin Receptors.

Autor: Ericson MD, Singh A; Departments of Medicinal Chemistry and Pharmacodynamics , University of Florida , Gainesville , Florida 32610 , United States., Tala SR; Departments of Medicinal Chemistry and Pharmacodynamics , University of Florida , Gainesville , Florida 32610 , United States., Haslach EM; Departments of Medicinal Chemistry and Pharmacodynamics , University of Florida , Gainesville , Florida 32610 , United States., Dirain MLS; Departments of Medicinal Chemistry and Pharmacodynamics , University of Florida , Gainesville , Florida 32610 , United States., Schaub JW; Departments of Medicinal Chemistry and Pharmacodynamics , University of Florida , Gainesville , Florida 32610 , United States., Flores V; Departments of Medicinal Chemistry and Pharmacodynamics , University of Florida , Gainesville , Florida 32610 , United States., Eick N; Departments of Medicinal Chemistry and Pharmacodynamics , University of Florida , Gainesville , Florida 32610 , United States., Lensing CJ, Freeman KT, Smeester BA, Adank DN, Wilber SL, Speth R; College of Pharmacy , Nova Southeastern University , Fort Lauderdale , Florida 33328 , United States.; Department of Pharmacology and Physiology , Georgetown University , Washington, D.C. 20057 , United States., Haskell-Luevano C; Departments of Medicinal Chemistry and Pharmacodynamics , University of Florida , Gainesville , Florida 32610 , United States.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2018 Apr 26; Vol. 61 (8), pp. 3738-3744. Date of Electronic Publication: 2018 Apr 09.