Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Dipti P. Rath"'
Autor:
Michael D. Waite, Pierre Marie L. Robitaille, Carlos A. A. Torres, Mark G. Angelos, Dipti P. Rath, Philip D. Beckley, Hui Zhu, Brian S. Palmer
Publikováno v:
Critical Care Medicine. 28:1503-1508
OBJECTIVE To determine whether epinephrine in combination with high flow worsens left ventricular (LV) myocardial high-energy phosphate stores during reperfusion of ischemic ventricular fibrillation (VF). DESIGN Blinded, prospective block randomized,
Publikováno v:
Annals of Emergency Medicine. 34:583-588
We sought to determine whether flow rates of approximately 60% of normal values are sufficient to preserve the left ventricular myocardial high-energy phosphate pool during ventricular fibrillation (VF).Mixed-breed swine (weight 22. 4+/-2.5 kg) were
Autor:
Dipti P. Rath, Hui Zhu, Carlos A. A. Torres, Pierre Marie L. Robitaille, Philip D. Beckley, Mark G. Angelos
Publikováno v:
Academic Emergency Medicine. 6:581-587
Objectives: Earlier work suggests the invivo heart alters its substrate utilization as a function of cardiac work. Previous work has also demonstrated the high oxygen requirements of the heart during ventricular fibrillation (VF). The authors hypothe
Autor:
Amir M. Abduljalil, Pierre Marie L. Robitaille, Dipti P. Rath, Robert L. Hamlin, Huzeng Zhang, J. M. O'donnell, Zongcheng Jiang
Publikováno v:
Journal of Biological Chemistry. 268:26296-26301
Oxidative metabolism in the in vivo canine myocardium was studied noninvasively using 13C-enriched acetate and non-steady state 13C NMR techniques. Under low workload conditions, the myocardium oxidized the infused [2-13C]acetate and incorporated the
Transaminase reaction rates, transport activities and TCA cycle analysis by post-steady state13C NMR
Autor:
Robert L. Hamlin, Thomas E Skinner, Pierre-Marie Robitaille, Dipti P. Rath, Amir M. Abduljalil
Publikováno v:
Magnetic Resonance in Medicine. 30:262-266
In this work, we present the post-steady state analysis of the TCA cycle and a closed form solution to the rate of label washout from the C4 carbon of glutamic acid through the transaminases and the malate-aspartate shuttle and then through alpha-ket
Publikováno v:
Magnetic Resonance in Medicine. 30:4-10
31P NMR spatial localization and saturation transfer techniques were combined to enable the transmural measurement of the forward creatine kinase (CK) rate (ATP:creatine N-phosphotransferase, EC 2.7.3.2.) in the in vivo canine myocardium. Five epicar
Autor:
Dipti P. Rath, Zongcheng Jiang, Pierre-Marie Robitaille, Hui Zhu, Robert L. Hamlin, Xiaoxin Tong
Publikováno v:
Magnetic resonance in medicine. 38(6)
In this work, substrate selection was monitored in the left ventricle of the canine myocardium by following pyruvate and lactate oxidation under in vivo conditions at basal and elevated workloads. These studies were conducted in the open chest model
Autor:
Amir M. Abduljalil, Anthony H. Aletras, Dipti P. Rath, H Zui, W C McCartney, P-M L Robitaille
Publikováno v:
Investigative radiology. 31(10)
RATIONALE AND OBJECTIVES A modified Fourier Series Window (FSW) method is introduced that provides a simple, reasonably accurate, solution to spatial localization for layers in nuclear magnetic resonance (NMR) spectroscopy. This method was developed
Publikováno v:
Critical care medicine. 23(4)
Objective: Myocardial metabolic requirements during reperfusion of ventricular fibrillation are poorly understood. The objective of this study was to determine if controlled reperfusion after a clinically relevant global ischemia period of 10 mins wa
Autor:
Amir M. Abduljalil, Zongchen Jiang, Dipti P. Rath, Robert L. Hamlin, Hui Zhu, Charles M. Little, Huzeng Zhang, Xiaoxin Tong, Pierre-Marie Robitaille, Charles G. Brown
Publikováno v:
Circulation. 91(2)
Background Transmural analyses of the creatine phosphate (CP)/ATP ratio in various lamina of the canine myocardium have previously revealed significant variations in the CP/ATP ratio, with the subendocardial layer displaying a decreased ratio relativ