Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Diphosphonates/pharmacology"'
Autor:
Frédéric Baron, Arnold Bolomsky, Elodie Duray, Jo Caers, Roy Heusschen, Joséphine Muller, Heinz Ludwig, Yves Beguin, Nadia Withofs, Eline Menu
Publikováno v:
Leukemia & Lymphoma. 59:14-28
Multiple myeloma (MM) bone disease is a major cause of morbidity and mortality in MM patients and persists even in patients in remission. This bone disease is caused by an uncoupling of bone remodeling, with increased osteoclast and decreased osteobl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::183515d0fc0c6aa5876c01201607f1c2
https://doi.org/10.1080/10428194.2017.1323272
https://doi.org/10.1080/10428194.2017.1323272
Publikováno v:
Osteoporosis International, Vol. 21, No 6 (2010) pp. 957-967
SUMMARY: We evaluated the effects of parathyroid hormone (PTH), pamidronate, or renutrition on osseointegration of titanium implants in the proximal tibia of rats subject to prolonged low-protein diets. PTH improved mechanical fixation, microarchitec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::440d110de24081f7f4f077d569fb2234
http://doc.rero.ch/record/322290/files/198_2009_Article_1031.pdf
http://doc.rero.ch/record/322290/files/198_2009_Article_1031.pdf
Glioblastoma multiforme (GBM) is the most common and aggressive brain tumor that affects older people. Although the current therapeutic approaches for GBM include surgical resection, radiotherapy, and chemotherapeutic agent temozolomide, the median s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3566::84e73484097c9982018e1764f259a03a
Autor:
Sylvain Contie, Philippe Clézardin, Nathalie Voorzanger-Rousselot, Serge Ferrari, Nicolas Bonnet, Patrick Garnero, Judith Litvin
Publikováno v:
Calcified tissue international
Calcified Tissue International, Vol. 87, No 4 (2010) pp. 341-350
Calcified Tissue International, Vol. 87, No 4 (2010) pp. 341-350
Periostin is a gamma-carboxyglutamic acid protein preferentially expressed in periosteum and bone mesenchymal stem cells. Lack of a precise assay for measuring circulating levels impairs the investigation of its biological significance. We developed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80771d8a13ad8b0937712f24c535aa90
Publikováno v:
Journal of Bone and Mineral Research, Vol. 22, No 10 (2007) pp. 1526-33
Protein deficiency is associated with impaired titanium osseointegration. We studied whether systemic treatment with PTH or pamidronate could influence the resistance to pull-out of titanium rods implanted into rats proximal tibia under normal and is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::036db70c9cbd12f632f3bf08c0ed3319
https://doi.org/10.1359/jbmr.070610
https://doi.org/10.1359/jbmr.070610
Autor:
Bruno Vincenzi, Daniele Santini, Alice Zoccoli, Loretta D'Onofrio, Michele Iuliani, Francesco Pantano, Vladimir Virzì, Giuseppe Tonini, Giulia Ribelli, Luciano Stumbo, Chiara Spoto, Marco Fioramonti
Publikováno v:
Breast Cancer Research : BCR
Breast cancer research, 17
Breast cancer research, 17
Bisphosphonates (BPs) are approved as standard therapy in breast cancer for the treatment of bone metastases, since they were demonstrated to reduce the prevalence of skeletal-related events including fractures and hypercalcemia. In the adjuvant sett
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b96a8d4b1095f575987c0b8be071075
http://hdl.handle.net/11573/1641535
http://hdl.handle.net/11573/1641535
Autor:
Domenico Bosco, Carmen Gonelle-Gispert, Dominique G. Rouiller, Claes B. Wollheim, Philippe A. Halban
Publikováno v:
Diabetes, Vol. 50, No 5 (2001) pp. 1039-1046
Rat islet beta-cells spread in response to glucose when attached on the matrix produced by a rat bladder carcinoma cell line (804G). Furthermore, in a mixed population of cells, it has been observed previously that spread cells secrete more insulin a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5671ef72668b9f701b5d840536860735
https://doi.org/10.2337/diabetes.50.5.1039
https://doi.org/10.2337/diabetes.50.5.1039
Autor:
Zheng Xiang, Yu-Lung Lau, Wenwei Tu, Iris H. Y. Ng, J. S. Malik Peiris, Gang Qin, Jian Zheng, Sin Fun Sia, Kwok-Tai Lam, Ming Liu, Yinping Liu
Publikováno v:
The Journal of Experimental Medicine
As shown in humanized mice, a population of Vγ9Vδ2 T cells can reduce the severity and mortality of disease caused by infection with human and avian influenza viruses.
There are few antiviral drugs for treating influenza, and the emergence of
There are few antiviral drugs for treating influenza, and the emergence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0775a514c8c16b41c497980b66447e71
http://hdl.handle.net/10722/139524
http://hdl.handle.net/10722/139524
Autor:
Aristotelis Bamias, Giorgos N. Papadopoulos, Konstantinos N. Syrigos, Meletios-Athanassios Dimopoulos, Evangelos Terpos, Christos Papadimitriou, Giannis Mountzios, Myron Mavrikakis
The molecular triad, which includes the receptor activator of nuclear factor kappa-B ligand (RANKL), its receptor RANK, and the endogenous soluble RANKL decoy receptor osteoprotegerin (OPG), has emerged as an important determinant of bone metabolism.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::558bf9010193fbb157bf07d6500e5529
http://olympias.lib.uoi.gr/jspui/handle/123456789/20183
http://olympias.lib.uoi.gr/jspui/handle/123456789/20183
Publikováno v:
Journal of Bone and Mineral Research, Vol. 24, No 5 (2009) pp. 800-808
Bone strength, a determinant of resistance to fracture, depends on BMD, geometry, microarchitecture, bone turnover rates, and properties of the bone at the material level. Despite comparable antifracture efficacy, anti-catabolics and bone anabolic ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16aec56470e2f0a3dd2edcb0276e333d
https://pubmed.ncbi.nlm.nih.gov/19063681
https://pubmed.ncbi.nlm.nih.gov/19063681