Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Dipendu Patra"'
Autor:
Chandra Sova Mandi, Tridib Mahata, Dipendu Patra, Jeet Chakraborty, Achyut Bora, Ritesh Pal, Sanjay Dutta
Publikováno v:
ACS Omega, Vol 7, Iss 8, Pp 6488-6501 (2022)
Externí odkaz:
https://doaj.org/article/1e4b3e8116b843feb398e5fe6e7bac85
Autor:
Dipendu Patra, Sanjay Dutta, Chandra Sova Mandi, K. S. Haseena, Gautam Basu, Sayanika Banerjee
Publikováno v:
ChemBioChem. 22:359-363
Transfer RNAs (tRNAs) are fundamental molecules in cellular translation. In this study we have highlighted a fluorescence-based perceptive approach for tRNAs by using a quinoxaline small molecule. We have synthesised a water-soluble fluorescent pyrim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e476d54908973475a2715acf8542866
https://doi.org/10.1002/cbic.202000584
https://doi.org/10.1002/cbic.202000584
Autor:
Sanjay Dutta, Dipendu Patra, Saumitra Das, Ajay Kanungo, Jeet Chakraborty, Bhim Majhi, Ritesh Ranjan Pal, Geetika Sharma, Krishna Kumar, Khondakar Sayef Ahammed, Saikat Chakrabarti, Tridib Mahata
Publikováno v:
Chemical Communications. 55:14027-14030
RNA-biased small molecules with a monoquinoxaline core target the L-shaped structure of subdomain IIa of Hepatitis C virus internal ribosome entry site (IRES) RNA in proximity to the Mg2+ binding site. The binding event leads to the destacking of RNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::764f4c0977a99430c97f70c2ba8307ec
https://doi.org/10.1039/c9cc06531h
https://doi.org/10.1039/c9cc06531h
Autor:
Ayan Datta, Sanjay Dutta, Rimita Saha, Dipendu Patra, Titas Kumar Mukhopadhyay, Amit Chakraborty, Jeet Chakraborty, Ajay Kanungo, Ritesh Ranjan Pal
Publikováno v:
European Journal of Medicinal Chemistry. 229:113995
Cooperative disruption of Watson-Crick hydrogen bonds, as well as base-destacking, is shown to be triggered by a quinoxaline-based small molecule consisting of an N,N-dimethylaminopropyl tether, and a para-substituted benzyl moiety. This events lead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::136c68df54a6c5533778d1389821e7ee
https://doi.org/10.1016/j.ejmech.2021.113995
https://doi.org/10.1016/j.ejmech.2021.113995
Publikováno v:
Biochemistry. 57:5557-5563
Small molecules that intercalate DNA have tremendous therapeutic potential. Typically, DNA intercalators do not alter the overall DNA double-helical structure, except locally at the intercalation sites. In a previous report, we showed that a quinoxal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfd79614a2a82b0dea0eff48ea8727b8
https://doi.org/10.1021/acs.biochem.8b00613
https://doi.org/10.1021/acs.biochem.8b00613
Autor:
Amit Chakraborty, Subhadeep Palit, Anindyajit Banerjee, Dipendu Patra, Sanghamitra Mukherjee, Partha Chakrabarti, Sanjay Dutta, Saikat Chakrabarti, Sougata Niyogi
Publikováno v:
ChemBioChem. 19:1720-1726
Nonalcoholic fatty liver disease (NAFLD), which is characterized by excess accumulation of triglyceride in hepatocytes, is the major cause of chronic liver disease worldwide and no approved drug is available. The mechanistic target of rapamycin (mTOR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72011a01285a4b6afc9e1031f822dfbe
https://doi.org/10.1002/cbic.201800271
https://doi.org/10.1002/cbic.201800271
Autor:
Sanjay Dutta, Dipendu Patra, Tridib Mahata, Prakas R. Maulik, Sanghamitra Mukherjee, Ajay Kanungo
Publikováno v:
RSC Advances. 5:70958-70967
We have developed a novel fluorescent scaffold 4 which is a 9-nitro-2,3-dihydro-1H-pyrimido[1,2-a]quinoxalin-5-amine derivative from the reaction between di-tert-butyl but-2-ynedioate and a quinoxaline molecule containing a dimethyl amine side tail i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cc865dc14537b8a21a6c1559b1713b7
https://doi.org/10.1039/c5ra12960e
https://doi.org/10.1039/c5ra12960e