Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Dipendra Bhandari"'
Autor:
Dipendra Bhandari, Kiran Kumar Adepu, Andriy Anishkin, Colin D. Kay, Erin E. Young, Kyle M. Baumbauer, Anuradha Ghosh, Sree V. Chintapalli
Publikováno v:
Metabolites, Vol 14, Iss 8, p 430 (2024)
Metabolomics, the study of small-molecule metabolites within biological systems, has become a potent instrument for understanding cellular processes. Despite its profound insights into health, disease, and drug development, identifying the protein pa
Externí odkaz:
https://doaj.org/article/97ffee8c048e417794e339be6ceeae61
Publikováno v:
Biomolecules, Vol 13, Iss 7, p 1138 (2023)
Myoglobin (Mb) interaction with the outer mitochondrial membrane (OMM) promotes oxygen (O2) release. However, comprehensive molecular details on specific contact regions of the OMM with oxygenated (oxy-) and deoxygenated (deoxy-)Mb are missing. We us
Externí odkaz:
https://doaj.org/article/bf5925ad680648eb9c3d2458b2cd4ba9
Autor:
Dipendra Bhandari, Sangita Kachhap, Geet Madhukar, Kiran Kumar Adepu, Andriy Anishkin, Jin-Ran Chen, Sree V. Chintapalli
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 23; Pages: 14778
Previous research has indicated that various metabolites belonging to phenolic acids (PAs), produced by gut microflora through the breakdown of polyphenols, help in promoting bone development and protecting bone from degeneration. Results have also s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4a986868cc62938056226fd90b49238
https://pubmed.ncbi.nlm.nih.gov/36499106
https://pubmed.ncbi.nlm.nih.gov/36499106
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 15; Pages: 8766
Myoglobin (Mb), besides its roles as an oxygen (O2) carrier/storage protein and nitric oxide NO scavenger/producer, may participate in lipid trafficking and metabolite binding. Our recent findings have shown that O2 is released from oxy-Mb upon inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::075d357648adbd28eae7cbfcbb6a5756
Publikováno v:
Journal of Molecular Modeling. 28
Acifran is a well-known agonist of G-protein-coupled receptor protein, namely GPR109A. Acifran is primarily used in the treatment of dyslipidemia, myocardial infractions, and atherosclerosis in humans due to its lower vascular and metabolic side effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6582af021e789ed4dc50cce5e5e0bda2
https://doi.org/10.1007/s00894-022-05233-5
https://doi.org/10.1007/s00894-022-05233-5
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 9; Pages: 4747
International journal of molecular sciences, vol 23, iss 9
International journal of molecular sciences, vol 23, iss 9
Myoglobin (Mb)-mediated oxygen (O2) delivery and dissolved O2 in the cytosol are two major sources that support oxidative phosphorylation. During intense exercise, lactate (LAC) production is elevated in skeletal muscles as a consequence of insuffici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5867282e67c3344035a8179207629518
Autor:
Ryan Kilgore, Wenning Chu, Dipendra Bhandari, David Fischler, Ruben G. Carbonell, Michael Crapanzano, Stefano Menegatti
Publikováno v:
Journal of Chromatography A. 1687:463701
Engineered multi-specific monoclonal antibodies (msAbs) and antibody fragments offer valuable therapeutic options against metabolic disorders, aggressive cancers, and viral infections. The advancement in molecular design and recombinant expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50afb5997661db075f4a58518654e5d3
https://doi.org/10.1016/j.chroma.2022.463701
https://doi.org/10.1016/j.chroma.2022.463701
Autor:
Dipendra Bhandari, Jae Sly, Augustus Adams, Michael Crapanzano, Hannah Reese, Stefano Menegatti, Chu Wenning, Sobhana A. Sripada
Publikováno v:
AIChE Journal. 67
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::872a5c5f4727de4506fa80b936836b57
https://doi.org/10.1002/aic.17482
https://doi.org/10.1002/aic.17482
This study presents the chromatographic purification of immunoglobulin G (IgG) from human plasma using a two-column process integrating the peptide-based adsorbents LigaGuardTM, which captures non-Ig plasma proteins in flow-through mode, and LigaTrap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::946f642c854b8797cceca105d28f733d
https://doi.org/10.22541/au.162603627.72082600/v1
https://doi.org/10.22541/au.162603627.72082600/v1
Autor:
Dipendra Bhandari, Tim Pouland, Doris M. Benbrook, Richard A. Bunce, Donghua H. Zhou, Suaad Abuskhuna, Maryam Mashayekhi, Krishna Kumar Gnanasekaran, K. Darrell Berlin
Publikováno v:
Bioorganic & Medicinal Chemistry. 28:115244
SHetA2 (NSC 721689), our lead Flex-Het anti-cancer agent, consists of a thiochroman (Ring A) and a 4-nitrophenyl (Ring B) linked by a thiourea bridge. In this work, several series of new analogs having a tetrahydroquinoline (THQ, Ring A) unit connect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7104530e5057faa39ab4396d6c96e260
https://doi.org/10.1016/j.bmc.2019.115244
https://doi.org/10.1016/j.bmc.2019.115244