Oncogenic pathway signatures predict the risk of progression and recurrence in well-differentiated pancreatic neuroendocrine tumors.

Autor: Mederos MA; Department of Surgery, University of California Los Angeles, Los Angeles, California, USA., Court CM; Mays Cancer Center, University of Texas Health San Antonio, San Antonio, Texas, USA., Dipardo BJ; Department of Surgery, University of California Los Angeles, Los Angeles, California, USA., Pisegna JR; Department of Molecular, Cellular, and Integrative Physiology, University of California Los Angeles, Los Angeles, California, USA., Dawson DW; Department of Pathology and Laboratory Medicine, University of California Los Angeles, Los Angeles, California, USA.; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, California, USA., Joe Hines O; Department of Surgery, University of California Los Angeles, Los Angeles, California, USA.; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, California, USA., Donahue TR; Department of Surgery, University of California Los Angeles, Los Angeles, California, USA.; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, California, USA.; Department of Molecular and Medical Pharmacology, University of California Los Angeles, Los Angeles, California, USA., Graeber TG; Department of Molecular, Cellular, and Integrative Physiology, University of California Los Angeles, Los Angeles, California, USA.; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, California, USA.; California NanoSystems Institute, University of California, Los Angeles, California, USA., Girgis MD; Department of Surgery, University of California Los Angeles, Los Angeles, California, USA.; Department of Surgery, Veterans Health Administration, Greater Los Angeles, Los Angeles, California, USA., Tomlinson JS; Department of Surgery, University of California Los Angeles, Los Angeles, California, USA.; Department of Surgery, Veterans Health Administration, Greater Los Angeles, Los Angeles, California, USA.

Publikováno v: Journal of surgical oncology [J Surg Oncol] 2024 Aug 19. Date of Electronic Publication: 2024 Aug 19.

Metastasis and Immune Evasion from Extracellular cGAMP Hydrolysis.

Autor: Li J; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York., Duran MA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York., Dhanota N; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York., Chatila WK; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.; Tri-Institutional Program in Computational Biology and Medicine, Weill Cornell Medical College, New York, New York., Bettigole SE; Volastra Therapeutics Inc., New York, New York., Kwon J; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York., Sriram RK; Meyer Cancer Center, Weill Cornell Medicine, New York, New York., Humphries MP; Precision Medicine Centre of Excellence, Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, United Kingdom., Salto-Tellez M; Precision Medicine Centre of Excellence, Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, United Kingdom.; Medical Sciences Division, Department of Oncology, University of Oxford, Oxford, United Kingdom., James JA; Precision Medicine Centre of Excellence, Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, United Kingdom., Hanna MG; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York., Melms JC; Columbia Center for Translational Immunology, New York, New York.; Division of Hematology and Oncology, Columbia University Medical Center, New York, New York., Vallabhaneni S; Laboratory for Systems Pharmacology, Harvard Medical School, Boston, Massachusetts., Litchfield K; Cancer Evolution and Genome Instability Laboratory, Francis Crick Institute, London, United Kingdom., Usaite I; Cancer Evolution and Genome Instability Laboratory, Francis Crick Institute, London, United Kingdom., Biswas D; Cancer Evolution and Genome Instability Laboratory, Francis Crick Institute, London, United Kingdom., Bareja R; Englander Institute for Precision Medicine, Meyer Cancer Center, Weill Cornell Medicine, New York, New York., Li HW; Columbia Center for Translational Immunology, New York, New York., Martin ML; Englander Institute for Precision Medicine, Meyer Cancer Center, Weill Cornell Medicine, New York, New York., Dorsaint P; Englander Institute for Precision Medicine, Meyer Cancer Center, Weill Cornell Medicine, New York, New York., Cavallo JA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York., Li P; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, New York., Pauli C; Institute for Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland., Gottesdiener L; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York., DiPardo BJ; Department of Surgery, University of California, Los Angeles, California., Hollmann TJ; Medical Sciences Division, Department of Oncology, University of Oxford, Oxford, United Kingdom., Merghoub T; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Medicine, Weill Cornell Medicine, New York, New York.; Ludwig Collaborative and Swim Across America Laboratory, Memorial Sloan Kettering Cancer Center, New York, New York.; Parker Institute for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, New York., Wen HY; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York., Reis-Filho JS; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York., Riaz N; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York., Su SM; Volastra Therapeutics Inc., New York, New York., Kalbasi A; Department of Radiation Oncology, Jonsson Comprehensive Cancer Center, University of California, Los Angeles, California., Vasan N; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Medicine, Weill Cornell Medicine, New York, New York., Powell SN; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York., Wolchok JD; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Medicine, Weill Cornell Medicine, New York, New York.; Ludwig Collaborative and Swim Across America Laboratory, Memorial Sloan Kettering Cancer Center, New York, New York.; Parker Institute for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, New York., Elemento O; Englander Institute for Precision Medicine, Meyer Cancer Center, Weill Cornell Medicine, New York, New York., Swanton C; Cancer Evolution and Genome Instability Laboratory, Francis Crick Institute, London, United Kingdom., Shoushtari AN; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Medicine, Weill Cornell Medicine, New York, New York., Parkes EE; Precision Medicine Centre of Excellence, Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, United Kingdom.; Medical Sciences Division, Department of Oncology, University of Oxford, Oxford, United Kingdom., Izar B; Columbia Center for Translational Immunology, New York, New York.; Division of Hematology and Oncology, Columbia University Medical Center, New York, New York., Bakhoum SF; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York. samuel.bakhoum@gmail.com.; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York.

Publikováno v: Cancer discovery [Cancer Discov] 2021 May; Vol. 11 (5), pp. 1212-1227. Date of Electronic Publication: 2020 Dec 28.

Low Rates of Chemotherapy Use for Primary, High-Grade Soft Tissue Sarcoma: A National Cancer Database Analysis.

Autor: Graham DS; Division of Surgical Oncology, Department of Surgery, University of California, Los Angeles, Los Angeles, California., Onyshchenko M; Division of Hematology-Oncology, Department of Internal Medicine, Harbor-UCLA Medical Center, Torrance, California., Eckardt MA; Division of Surgical Oncology, Department of Surgery, University of California, Los Angeles, Los Angeles, California.; Department of Surgery, Yale School of Medicine, New Haven, Connecticut.; Department of Surgery, Greater Los Angeles Veterans Health Administration, Los Angeles, California., DiPardo BJ; Division of Surgical Oncology, Department of Surgery, University of California, Los Angeles, Los Angeles, California.; Department of Surgery, Greater Los Angeles Veterans Health Administration, Los Angeles, California., Venigalla S; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Nelson SD; Department of Pathology., Chmielowski B; Division of Hematology-Oncology, Department of Internal Medicine, and.; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, California., Singh AS; Division of Hematology-Oncology, Department of Internal Medicine, and.; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, California., Shabason JE; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; and., Eilber FC; Division of Surgical Oncology, Department of Surgery, University of California, Los Angeles, Los Angeles, California.; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, California., Kalbasi A; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, California.; Department of Radiation Oncology, University of California, Los Angeles, Los Angeles, California.

Publikováno v: Journal of the National Comprehensive Cancer Network : JNCCN [J Natl Compr Canc Netw] 2020 Aug; Vol. 18 (8), pp. 1055-1065.

Cancer Modeling-on-a-Chip with Future Artificial Intelligence Integration.

Autor: Fetah KL; Center for Minimally Invasive Therapeutics, University of California, Los Angeles, CA, 90095, USA.; California NanoSystems Institute (CNSI), University of California, 570 Westwood Plaza, Los Angeles, CA, 90095, USA.; Department of Bioengineering, University of California, Los Angeles, CA, 90095, USA., DiPardo BJ; Department of Surgery, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA., Kongadzem EM; School of Technology and Innovations, University of Vaasa, FI-65101, Vaasa, Finland., Tomlinson JS; Department of Surgery, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA., Elzagheid A; Biotechnology Research Center, Libyan Authority for Research, Science and Technology, Tripoli, Libya., Elmusrati M; School of Technology and Innovations, University of Vaasa, FI-65101, Vaasa, Finland., Khademhosseini A; Center for Minimally Invasive Therapeutics, University of California, Los Angeles, CA, 90095, USA.; California NanoSystems Institute (CNSI), University of California, 570 Westwood Plaza, Los Angeles, CA, 90095, USA.; Department of Bioengineering, University of California, Los Angeles, CA, 90095, USA.; Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA., Ashammakhi N; Center for Minimally Invasive Therapeutics, University of California, Los Angeles, CA, 90095, USA.; California NanoSystems Institute (CNSI), University of California, 570 Westwood Plaza, Los Angeles, CA, 90095, USA.; Department of Bioengineering, University of California, Los Angeles, CA, 90095, USA.; School of Technology and Innovations, University of Vaasa, FI-65101, Vaasa, Finland.; Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA.; Division of Plastic Surgery, Department of Surgery, Oulu University, FI-9001, Oulu, Finland.

Publikováno v: Small (Weinheim an der Bergstrasse, Germany) [Small] 2019 Dec; Vol. 15 (50), pp. e1901985. Date of Electronic Publication: 2019 Nov 13.

Pancreatic cancer circulating tumor cells: applications for personalized oncology.

Autor: DiPardo BJ; a Department of Surgery , University of California Los Angeles , Los Angeles , CA , USA.; b Department of Surgery , Greater Los Angeles Veterans Health Administration , Los Angeles , CA , USA., Winograd P; a Department of Surgery , University of California Los Angeles , Los Angeles , CA , USA.; b Department of Surgery , Greater Los Angeles Veterans Health Administration , Los Angeles , CA , USA., Court CM; a Department of Surgery , University of California Los Angeles , Los Angeles , CA , USA.; b Department of Surgery , Greater Los Angeles Veterans Health Administration , Los Angeles , CA , USA., Tomlinson JS; a Department of Surgery , University of California Los Angeles , Los Angeles , CA , USA.; b Department of Surgery , Greater Los Angeles Veterans Health Administration , Los Angeles , CA , USA.

Publikováno v: Expert review of molecular diagnostics [Expert Rev Mol Diagn] 2018 Sep; Vol. 18 (9), pp. 809-820. Date of Electronic Publication: 2018 Aug 22.