Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Dipankar Ash"'
Autor:
Dipankar Ash, Varadarajan Sudhahar, Seock-Won Youn, Mustafa Nazir Okur, Archita Das, John P. O’Bryan, Maggie McMenamin, Yali Hou, Jack H. Kaplan, Tohru Fukai, Masuko Ushio-Fukai
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The role of endothelial copper transporter ATP7A in vascular function and angiogenesis remains largely unexplored. Here the authors show that ATP7A promotes VEGFR2 signaling and angiogenesis by limiting autophagy-mediated degradation of VEGFR2, which
Externí odkaz:
https://doaj.org/article/7349411310e2453bb951aceb39ac7122
Dichotomous Role of Tumor Necrosis Factor in Pulmonary Barrier Function and Alveolar Fluid Clearance
Autor:
Rudolf Lucas, Yalda Hadizamani, Perenlei Enkhbaatar, Gabor Csanyi, Robert W. Caldwell, Harald Hundsberger, Supriya Sridhar, Alice Ann Lever, Martina Hudel, Dipankar Ash, Masuko Ushio-Fukai, Tohru Fukai, Trinad Chakraborty, Alexander Verin, Douglas C. Eaton, Maritza Romero, Jürg Hamacher
Publikováno v:
Frontiers in Physiology, Vol 12 (2022)
Alveolar-capillary leak is a hallmark of the acute respiratory distress syndrome (ARDS), a potentially lethal complication of severe sepsis, trauma and pneumonia, including COVID-19. Apart from barrier dysfunction, ARDS is characterized by hyper-infl
Externí odkaz:
https://doaj.org/article/d53e89e04334424ea4b796d4f522406c
Autor:
Sheela Nagarkoti, Young-Mee Kim, Dipankar Ash, Archita Das, Eric Vitriol, Tracy-Ann Read, Seock-Won Youn, Varadarajan Sudhahar, Malgorzata McMenamin, Yali Hou, Harriet Boatwright, Ruth Caldwell, David W. Essex, Jaehyung Cho, Tohru Fukai, Masuko Ushio-Fukai
Publikováno v:
Angiogenesis
VEGFR2 signaling in endothelial cells (ECs) is regulated by reactive oxygen species (ROS) derived from NADPH oxidases (NOXs) and mitochondria, which plays an important role in postnatal angiogenesis. However, it remains unclear how highly diffusible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42217c0f2a55a44dc426f7b14f075998
https://doi.org/10.1007/s10456-022-09852-7
https://doi.org/10.1007/s10456-022-09852-7
Autor:
Archita Das, Dipankar Ash, Abdelrahman Y. Fouda, Varadarajan Sudhahar, Young-Mee Kim, Yali Hou, Farlyn Z. Hudson, Brian K. Stansfield, Ruth B. Caldwell, Malgorzata McMenamin, Rodney Littlejohn, Huabo Su, Maureen R. Regan, Bradley J. Merrill, Leslie B. Poole, Jack H. Kaplan, Tohru Fukai, Masuko Ushio-Fukai
Publikováno v:
Nature Cell Biology. 24:35-50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a66cbb2e93d1f03c98da39f941c33b8
https://doi.org/10.1038/s41556-021-00822-7
https://doi.org/10.1038/s41556-021-00822-7
Autor:
Tohru Fukai, David Fulton, Sheela Nagarkoti, Masuko Ushio-Fukai, Dipankar Ash, Eric J. Belin de Chantemèle
Publikováno v:
Antioxid Redox Signal
Reactive oxygen species (ROS; e.g., superoxide [O(2)(•−)] and hydrogen peroxide [H(2)O(2)]) and reactive nitrogen species (RNS; e.g., nitric oxide [NO(•)]) at the physiological level function as signaling molecules that mediate many biological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5a741f0a35c496a83484b42414e8be5
https://doi.org/10.1089/ars.2020.8161
https://doi.org/10.1089/ars.2020.8161
Autor:
Aarif Ali, Sadaf Ali, Shafat Ali, Sofi Imtiyaz Ali, Mehvish Altaf, Shiekh Amir, Dipankar Ash, Haamid Bashir, Showkeen Muzamil Bashir, Amrita Bhat, Mohammad Hayat Bhat, Mohammad Salim Bhat, Mashooq Ahmad Dar, Doli Das, Rafiqa Eachkoti, Iqra Farooq, Parveena Firdous, Alveena Ganai, Showkat Ahmad Ganie, Younis Ahmad Hajam, Syed Suhail Hamdani, Tahir Hussain, Qadir Jasiya, Qudratullah Kalwar, Mosin Saleem Khan, Rajesh Kumar, Rakesh Kumar, Sabhiya Majid, Bashir Ahmad Malla, Sanju Mandal, Zainab Manzoor, Illiyas Maqbool, Irfan Maqbool, Irfan Maqbool Sheikh, Peerzada Tajamul Mumtaz, Umar Muzaffer, Showkeen Muzamil, Nusrat Nabi, Showkat Ul Nabi, Faizan- i- Asrar Nazki, Kamran Nissar, V.I. Paul, Naieem Ahmad Pir, null Premlata, Khushbu Priya, Raies A. Qadri, Hakim Ali Qanoon, Geeta Rai, Raksha Rani, Nadeem Rashid, Muzafar Ahmad Rather, Muneeb U. Rehman, Tamasi Roy, Tajali Sahar, Iram Shabir, Aaliya Shah, Ruchi Shah, Preeti Sharma, Riya Sharma, Wajid Mohammad Sheikh, Saima Tabassum, Hiral Thacker, Manzoor Ur Rahman Mir, Javaid Ahmed Wani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::617fb77559e3c6c1349e8f1ed4138b4d
https://doi.org/10.1016/b978-0-323-90250-2.00022-4
https://doi.org/10.1016/b978-0-323-90250-2.00022-4
Autor:
Archita Das, Dipankar Ash, Tetsuo Horimatsu, Tohru Fukai, Masuko Ushio-Fukai, Bhupesh Singla, Silvia Leanhart, Ha Won Kim, Olga Antipova, Gabor Csanyi, David J. Fulton, Joseph White, Neal L. Weintraub, Varadarajan Sudhahar, Stefan Vogt, Jack H. Kaplan
Publikováno v:
Arterioscler Thromb Vasc Biol
Objective: Copper (Cu) is essential micronutrient, and its dysregulation is implicated in aortic aneurysm (AA) development. The Cu exporter ATP7A (copper-transporting P-type ATPase/Menkes ATPase) delivers Cu via the Cu chaperone Atox1 (antioxidant 1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3203458cc2f43b86790109498730b28
https://doi.org/10.1161/atvbaha.119.313374
https://doi.org/10.1161/atvbaha.119.313374
Autor:
Mustafa Nazir Okur, Sudhahar Varadarajan, Tohru Fukai, Seock Won Youn, Jack H. Kaplan, Dipankar Ash, Xuexiu Fang, Masuko Ushio-Fukai, Yali Hou, John P O'Brien, Malgorzata McMenamin
Publikováno v:
Circulation. 142
Background: VEGFR2 (KDR/Flk1) signaling in endothelial cells (ECs) plays a central role in angiogenesis. Copper (Cu) is essential micronutrient and has been implicated in angiogenesis. The P-type ATPase transporter ATP7A is key regulator of Cu homeos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbd8a4c5be24f6b2e6d81335757f6748
https://doi.org/10.1161/circ.142.suppl_3.13610
https://doi.org/10.1161/circ.142.suppl_3.13610
Autor:
Archita, Das, Dipankar, Ash, Abdelrahman Y, Fouda, Varadarajan, Sudhahar, Young-Mee, Kim, Yali, Hou, Farlyn Z, Hudson, Brian K, Stansfield, Ruth B, Caldwell, Malgorzata, McMenamin, Rodney, Littlejohn, Huabo, Su, Maureen R, Regan, Bradley J, Merrill, Leslie B, Poole, Jack H, Kaplan, Tohru, Fukai, Masuko, Ushio-Fukai
Publikováno v:
Nature cell biology. 24(1)
Vascular endothelial growth factor receptor type 2 (VEGFR2, also known as KDR and FLK1) signalling in endothelial cells (ECs) is essential for developmental and reparative angiogenesis. Reactive oxygen species and copper (Cu) are also involved in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dd0c1318e87e719fe51e24c7ae2621dc
https://pubmed.ncbi.nlm.nih.gov/35027734
https://pubmed.ncbi.nlm.nih.gov/35027734