Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Dipak Sarnobat"'
Autor:
Dipak Sarnobat, Ryan A Lafferty, R Charlotte Moffett, Andrei I Tarasov, Peter R Flatt, Nigel Irwin
Publikováno v:
Journal of Pharmacy and Pharmacology. 74:1758-1764
Objectives The antimalarial drug artemether is suggested to effect pancreatic islet cell transdifferentiation, presumably through activation γ-aminobutyric acid receptors, but this biological action is contested. Methods We have investigated changes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a35bde8caa538348818407fb93f8e6a2
https://doi.org/10.1093/jpp/rgac075
https://doi.org/10.1093/jpp/rgac075
Autor:
Dipak Sarnobat, R. Charlotte Moffett, Jinfang Ma, Peter R. Flatt, Neville H. McClenaghan, Andrei I. Tarasov
Publikováno v:
BioFactors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3869b5ed168431f92f8fce5f6a678943
https://doi.org/10.1002/biof.1938
https://doi.org/10.1002/biof.1938
Publikováno v:
Biochemical pharmacology. 199
Poorly controlled diabetes is characterised by a partial or complete loss of pancreatic islet β-cells, which deprives the remaining islet cells of important β-cell-derived soluble signals, such as insulin or GABA. We aimed to dissect the role of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4b9134e9c688144c4776c68b8f290cb
https://pubmed.ncbi.nlm.nih.gov/35358478
https://pubmed.ncbi.nlm.nih.gov/35358478
Autor:
Neil Tanday, Charlotte Moffett, Fiona M. Gribble, Dipak Sarnobat, Andrei I Tarasov, Peter R. Flatt, Frank Reimann
Publikováno v:
Biochem Pharmacol
Gut incretins, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP), enhance secretion of insulin in a glucose-dependent manner, predominantly by elevating cytosolic levels of cAMP in pancreatic β-cells. Successful targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1afa043a35f99863e5a48e46e761acaf
https://doi.org/10.1101/2020.08.03.234070
https://doi.org/10.1101/2020.08.03.234070
Autor:
Dipak Sarnobat, Neil Tanday, Charlotte Moffett, Victor A. Gault, Nigel Irwin, Fiona M. Gribble, Frank Reimann, Peter R. Flatt
Enzyme-resistant long-acting forms of the gut-derived peptide hormones, glucose-dependent insulinotropic polypeptide (GIP), xenin and oxyntomodulin (Oxm) have been generated, and exert beneficial effects on diabetes control and pancreatic islet archi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::807c0640bf70b56ad808647cebb927d8