Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Dipak Maskey"'
Publikováno v:
Cells, Vol 5, Iss 1, p 6 (2016)
Cilia and flagella are evolutionarily conserved, membrane-bound, microtubule-based organelles on the surface of most eukaryotic cells. They play important roles in coordinating a variety of signaling pathways during growth, development, cell mobility
Externí odkaz:
https://doaj.org/article/949b7a3abcae4b52ba20dda5c215265f
Autor:
Dipak Maskey, Pablo Ortiz
Publikováno v:
Physiology. 38
Mutations in the ALMS1 gene in humans cause Alström syndrome, characterized by progressive metabolic alterations that include obesity, hypertension, and chronic kidney disease (CKD). SNPs in the ALMS1 gene in the general population are associated wi
Autor:
Pablo A. Ortiz, Moomal N. Khan, Jerry Yee, Yuvraj Sharma, Shannon L. Murray, Adrian H. Ormsby, Kausik Umanath, Paulo S. Caceres, Jamie Fitzgerald, Steven R. Bolin, Gina Savickas, Junior Uduman, Albert M. Levin, Tang-Dong Liao, Dipak Maskey, Sarah Sarkar
Publikováno v:
J Am Soc Nephrol
BACKGROUND: AKI is a complication of coronavirus disease 2019 (COVID-19) that is associated with high mortality. Despite documented kidney tropism of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), there are no consistent reports of
Publikováno v:
The FASEB Journal. 36
Publikováno v:
The FASEB Journal. 35
Publikováno v:
Hypertension. 74
A large fraction of patients with diabetes mellitus develop diabetic nephropathy and are hypertensive. The Akita mice is one of the few mouse models of diabetes mellitus with features of the human disease including hypertension and kidney damage. Pre
Publikováno v:
The FASEB Journal. 34:1-1
Autor:
Mariela Mendez, Dipak Maskey, Keyona N King-Medina, Indrani Datta, Juergen K Naggert, Pablo A. Ortiz, Paulo S. Caceres, William H. Beierwaltes, Ankita Bachhawat Jaykumar, Tang-Dong Liao
Publikováno v:
JCI insight. 3(21)
Elevated blood pressure (BP) and renal dysfunction are complex traits representing major global health problems. Single nucleotide polymorphisms identified by genome-wide association studies have identified the Alström syndrome 1 (ALMS1) gene locus
Autor:
Uyen Tran, Terry Watnick, Jacob Keeling, Chang Xi Bai, Seokho Kim, Hongguang Nie, Oliver Wessely, Vasyl Nesin, Patricia Outeda, Dipak Maskey, Leonidas Tsiokas
Publikováno v:
Nature cell biology
WNT ligands induce Ca(2+) signalling on target cells. PKD1 (polycystin 1) is considered an orphan, atypical G-protein-coupled receptor complexed with TRPP2 (polycystin 2 or PKD2), a Ca(2+)-permeable ion channel. Inactivating mutations in their genes
Autor:
E-Ching Ong, Dipak Maskey, Sehyun Kim, Leonidas Tsiokas, Seokho Kim, Guangpu Li, Matthew Caleb Marlin
Publikováno v:
The EMBO journal. 34(19)
Primary cilia start forming within the G1 phase of the cell cycle and continue to grow as cells exit the cell cycle (G0). They start resorbing when cells re-enter the cell cycle (S phase) and are practically invisible in mitosis. The mechanisms by wh