Zobrazeno 1 - 10 of 456 pro vyhledávání: '"Dipak K Sarkar"'
1
Akademický článek
Ethanol-activated microglial exosomes induce MCP1 signaling mediated death of stress-regulatory proopiomelanocortin neurons in the developing hypothalamus
Autor: Prashant Tarale, Shaista Chaudhary, Sayani Mukherjee, Dipak K. Sarkar
Publikováno v: Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Background Microglia, a type of resident immune cells within the central nervous system, have been implicated in ethanol-activated neuronal death of the stress regulatory proopiomelanocortin (POMC) neuron-producing β-endorphin peptides in t
Externí odkaz: https://doaj.org/article/2bb1f6a8ceb248b391165fa9f3b2a863
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2
Akademický článek
Altered circadian expression of clock genes and clock-regulatory epigenetic modifiers in saliva of children with fetal alcohol spectrum disorders
Autor: Ujjal Das, Jennifer D. Thomas, Prashant Tarale, Jackie Soja, Sarah Inkelis, Christina Chambers, Dipak K. Sarkar
Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Prenatal alcohol-exposed (AE) infants and children often demonstrate disrupted sleep patterns, including more frequent awakenings, reduced total sleep time, and more night-to-night sleep variability. Despite the strong connection between sle
Externí odkaz: https://doaj.org/article/bcf676dbb5cd4f8e9877d2c5307ee53c
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3
Akademický článek
Beta 2 adrenergic receptor and mu opioid receptor interact to potentiate the aggressiveness of human breast cancer cell by activating the glycogen synthase kinase 3 signaling
Autor: Bénédicte Rousseau, Sengottuvelan Murugan, Ajay Palagani, Dipak K. Sarkar
Publikováno v: Breast Cancer Research, Vol 24, Iss 1, Pp 1-17 (2022)
Abstract Background Opioid and beta-adrenergic receptors are recently shown to cross talk via formation of receptor heterodimers to control the growth and proliferation of breast cancer cells. However, the underlying cell signaling mechanism remained
Externí odkaz: https://doaj.org/article/9cf7d8b521de4da1a6cb13e5a9c3230c
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4
Akademický článek
Neuroimmune Interactions in Fetal Alcohol Spectrum Disorders: Potential Therapeutic Targets and Intervention Strategies
Autor: Sayani Mukherjee, Prashant Tarale, Dipak K. Sarkar
Publikováno v: Cells, Vol 12, Iss 18, p 2323 (2023)
Fetal alcohol spectrum disorders (FASD) are a set of abnormalities caused by prenatal exposure to ethanol and are characterized by developmental defects in the brain that lead to various overt and non-overt physiological abnormalities. Growing eviden
Externí odkaz: https://doaj.org/article/41e203348a2743aabaa116aa38aa3840
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5
Akademický článek
Transgenerational inheritance of fetal alcohol effects on proopiomelanocortin gene expression and methylation, cortisol response to stress, and anxiety-like behaviors in offspring for three generations in rats: Evidence for male germline transmission.
Autor: Omkaram Gangisetty, Shaista Chaudhary, Ajay Palagani, Dipak K Sarkar
Publikováno v: PLoS ONE, Vol 17, Iss 2, p e0263340 (2022)
Previously it has been shown that fetal alcohol exposure increases the stress response partly due to lowering stress regulatory proopiomelanocortin (Pomc) gene expression in the hypothalamus via epigenetic mechanisms for multiple generations in mixed
Externí odkaz: https://doaj.org/article/904770a9b9fa48d3afa9e5d40c81c3a3
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6
Akademický článek
Sex-Determining Region Y Controls the Effects of Fetal Alcohol Exposure on Proopiomelanocortin Gene Expression
Autor: Omkaram Gangisetty, Edward A. Mead, Dipak K. Sarkar
Publikováno v: Frontiers in Neuroscience, Vol 15 (2021)
Fetal alcohol exposure (FAE) causes various neurodevelopmental deficits in offspring, including reduced expression of the stress regulatory proopiomelanocortin (Pomc) gene and an elevated stress response for multiple generations via the male germline
Externí odkaz: https://doaj.org/article/e38903ce4b2f44cbbdad02290fcb15b2
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8
Akademický článek
Mu-opioid receptor and delta-opioid receptor differentially regulate microglial inflammatory response to control proopiomelanocortin neuronal apoptosis in the hypothalamus: effects of neonatal alcohol
Autor: Pallavi Shrivastava, Miguel A. Cabrera, Lucy G. Chastain, Nadka I. Boyadjieva, Shaima Jabbar, Tina Franklin, Dipak K. Sarkar
Publikováno v: Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-19 (2017)
Abstract Background Opioid receptors are known to control neurotransmission of various peptidergic neurons, but their potential role in regulation of microglia and neuronal cell communications is unknown. We investigated the role of mu-opioid recepto
Externí odkaz: https://doaj.org/article/2c8939c8a05e4e2aa49bbcd3cb180ef4
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10
Supplementary Figure 2 from Beta-Endorphin Cell Therapy for Cancer Prevention
Autor: Dipak K. Sarkar, Pallavi Shrivastava, Shaima Jabbar, Nadka Boyadjieva, Sengottuvelan Murugan, Changqing Zhang
SFigure 2: Representative picture of a back tumor, which developed in some control neuron transplanted animals following intravenous injection of MADB106 cells in female F344 rats.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9687631237bccecede1b88e0ed4cddd5
https://doi.org/10.1158/1940-6207.22525638.v1
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