Single-cell characterisation of tissue homing CD4 + and CD8 + T cell clones in immune-mediated refractory arthritis

Autor: Dipabarna Bhattacharya, Jason Theodoropoulos, Katariina Nurmi, Timo Juutilainen, Kari K. Eklund, Riitta Koivuniemi, Tiina Kelkka, Satu Mustjoki, Tapio Lönnberg

Publikováno v: Molecular Medicine, Vol 30, Iss 1, Pp 1-14 (2024)

Abstract Background Immune-mediated arthritis is a group of autoinflammatory diseases, where the patient’s own immune system attacks and destroys synovial joints. Sustained remission is not always achieved with available immunosuppressive treatment

Externí odkaz: https://doaj.org/article/4866510c6d044ed084fbba8696a56782

Identification of novel STAT5B mutations and characterization of TCRβ signatures in CD4+ T-cell large granular lymphocyte leukemia

Autor: Dipabarna Bhattacharya, Antonella Teramo, Vanessa Rebecca Gasparini, Jani Huuhtanen, Daehong Kim, Jason Theodoropoulos, Gianluca Schiavoni, Gregorio Barilà, Cristina Vicenzetto, Giulia Calabretto, Monica Facco, Toru Kawakami, Hideyuki Nakazawa, Brunangelo Falini, Enrico Tiacci, Fumihiro Ishida, Gianpietro Semenzato, Tiina Kelkka, Renato Zambello, Satu Mustjoki

Publikováno v: Blood Cancer Journal, Vol 12, Iss 2, Pp 1-12 (2022)

Abstract CD4+ T-cell large granular lymphocyte leukemia (T-LGLL) is a rare subtype of T-LGLL with unknown etiology. In this study, we molecularly characterized a cohort of patients (n = 35) by studying their T-cell receptor (TCR) repertoire and the p

Externí odkaz: https://doaj.org/article/301d196f876344169d0f3ab949749ead

Adult-Onset Anti-Citrullinated Peptide Antibody-Negative Destructive Rheumatoid Arthritis Is Characterized by a Disease-Specific CD8+ T Lymphocyte Signature

Autor: Tiina Kelkka, Paula Savola, Dipabarna Bhattacharya, Jani Huuhtanen, Tapio Lönnberg, Matti Kankainen, Kirsi Paalanen, Mikko Tyster, Maija Lepistö, Pekka Ellonen, Johannes Smolander, Samuli Eldfors, Bhagwan Yadav, Sofia Khan, Riitta Koivuniemi, Christopher Sjöwall, Laura L. Elo, Harri Lähdesmäki, Yuka Maeda, Hiroyoshi Nishikawa, Marjatta Leirisalo-Repo, Tuulikki Sokka-Isler, Satu Mustjoki

Publikováno v: Frontiers in Immunology, Vol 11 (2020)

Rheumatoid arthritis (RA) is a complex autoimmune disease targeting synovial joints. Traditionally, RA is divided into seropositive (SP) and seronegative (SN) disease forms, the latter consisting of an array of unrelated diseases with joint involveme

Externí odkaz: https://doaj.org/article/269cd4fa96c4412898c4b325a9f2ac64

Increased Physiological GDNF Levels Have No Effect on Dopamine Neuron Protection and Restoration in a Proteasome Inhibition Mouse Model of Parkinson’s Disease

Autor: Soophie Olfat, Kärt Mätlik, Jaakko J. Kopra, Daniel R. Garton, Vilma H. Iivanainen, Dipabarna Bhattacharya, Johan Jakobsson, T. Petteri Piepponen, Jaan-Olle Andressoo

Parkinson’s disease (PD) is a progressive neurodegenerative disease that comprises a range of motor and nonmotor symptoms. Glial cell line-derived neurotrophic factor (GDNF) promotes the survival of dopamine neuronsin vitroandin vivo, and intracran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe949a3da471338d59b76bbca6ce140f
http://hdl.handle.net/10138/358547

List of contributors

Autor: Aniruddha Adhikari, Sangita Agarwal, Khushi Ahuja, S.T. Anne Sahithi, Priya Arumugam, Kannappan Arunachalam, Biswarup Banerjee, Deblina Banerjee, Ritwik Banerjee, Adreeja Basu, Medha Basu, Souradip Basu, Gargi Bhattacharjee, Debasmita Bhattacharya, Dipabarna Bhattacharya, Archisman Bhunia, Sayari Bhunia, Avijit Chakraborty, Navjyoti Chakraborty, Runu Chakraborty, Anwesha Chatterjee, Sayan Chatterjee, Amit Chattopadhyay, Shubhangi Chaudhary, Shi Chunlei, Soumendra Darbar, Nitisranjan Das, Sanchari Das, Anchita Das Sharma, Ananya Datta, MubarakAli Davoodbasha, Subhamoy Dey, Bandita Dutta, Chaitali Dutta, Abigail Fernandes, Sayak Ganguli, Sayantani Garai, Chandradipa Ghosh, Dipankar Ghosh, Priyam Ghosh, Siddhartha Sankar Ghosh, Sougata Ghosh, Jigresh Gohil, Nisarg Gohil, Kartik Chandra Guchhait, Parameswar Krishnan Iyer, Debarati Jana, Renitta Jobby, Aditi Joshi, Sanket Joshi, Khushal Khambhati, Prattusha Khan, Shivani Kumar, Vinod Kumar, Dibyajit Lahiri, Selvaraj Alagu Lakshmi, Medha Maitra, Suparna Majumder, Tirtha Pratim Mandal, Rupesh Maurya, Sutapa Roy Misra, Arup Kumar Mitra, Madhura Mondal, Subrata Mondal, Ebrahim Mostafavi, Dipro Mukherjee, Sayantani Mukhopadhyay, Moupriya Nag, Sanjay Nagarajan, Omkar Nalawade, Amiya Kumar Panda, Nayana Patil, Anuttam Patra, Marttin Paulraj Gundupalli, Venkata Giridhar Poosarla, Ram Singh Purty, Gobinath Rajagopalan, Suresh Ramakrishna, Rina Rani Ray, Banani Ray Chowdhury, Hirakjyoti Roy, Joyjit Saha, Srimoyee Saha, Sharmistha Samanta, Joseph Saoud, Bishwarup Sarkar, Moitrayee Sarkar, Sampriti Sarkar, Tanmay Sarkar, Sarani Sen, Arghya Sett, Vinodhini Shanmugam, Nagaveni Shivshetty, Paramjeet Singh, Priyanka Singh, Vijai Singh, Aruna Sivaram, Malinee Sriariyanun, Sirikanjana Thongmee, Vijay Upadhye, Apoorva Vashisht, Sumit Kumar Verma, Pranay Yadav

Publikováno v: Lantibiotics as Alternative Therapeutics ISBN: 9780323991414

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8b837cbe9ba9a3b82e3c5d9f4dc3d471
https://doi.org/10.1016/b978-0-323-99141-4.00028-x