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A super minigene with a short promoter and truncated introns recapitulates essential features of transcription and splicing regulation of the SMN1 and SMN2 genes.

Autor: Ottesen EW; Department of Biomedical Sciences, Iowa State University, Ames, IA 50011, USA., Seo J; Department of Biomedical Sciences, Iowa State University, Ames, IA 50011, USA., Luo D; Department of Biomedical Sciences, Iowa State University, Ames, IA 50011, USA., Singh NN; Department of Biomedical Sciences, Iowa State University, Ames, IA 50011, USA., Singh RN; Department of Biomedical Sciences, Iowa State University, Ames, IA 50011, USA.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2024 Apr 24; Vol. 52 (7), pp. 3547-3571.

ERK inhibitor: A candidate enhancing therapeutic effects of conventional chemo-radiotherapy in esophageal squamous cell carcinoma.

Autor: Song Y; Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China., Cheng Y; Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China., Lan T; Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China., Bai Z; Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China., Liu Y; Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China., Bi Z; Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China., Alu A; Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China., Cheng D; Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China., Wei Y; Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China., Wei X; Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China. Electronic address: xiaweiwei@scu.edu.cn.

Publikováno v: Cancer letters [Cancer Lett] 2023 Feb 01; Vol. 554, pp. 216012. Date of Electronic Publication: 2022 Dec 05.

High Concentration of an ISS-N1-Targeting Antisense Oligonucleotide Causes Massive Perturbation of the Transcriptome.

Autor: Ottesen EW; Department of Biomedical Sciences, Iowa State University, Ames, IA 50011, USA., Luo D; Department of Biomedical Sciences, Iowa State University, Ames, IA 50011, USA., Singh NN; Department of Biomedical Sciences, Iowa State University, Ames, IA 50011, USA., Singh RN; Department of Biomedical Sciences, Iowa State University, Ames, IA 50011, USA.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2021 Aug 04; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 04.

Skip metastasis in mediastinal lymph node is a favorable prognostic factor in N2 lung cancer patients: a meta-analysis.

Autor: Wang Z; Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China.; West China School of Medicine, Sichuan University, Chengdu, China., Cheng J; Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China.; West China School of Medicine, Sichuan University, Chengdu, China.; Department of Pathology, School of Medicine, Stanford University, Palo Alto, CA, USA.; Stanford Blood Center, Palo Alto, CA, USA., Huang W; West China School of Medicine, Sichuan University, Chengdu, China., Cheng D; West China School of Medicine, Sichuan University, Chengdu, China., Liu Y; West China School of Medicine, Sichuan University, Chengdu, China., Pu Q; Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China.; West China School of Medicine, Sichuan University, Chengdu, China., Reticker-Flynn NE; Department of Pathology, School of Medicine, Stanford University, Palo Alto, CA, USA.; Stanford Blood Center, Palo Alto, CA, USA., Liu L; Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China.; West China School of Medicine, Sichuan University, Chengdu, China.

Publikováno v: Annals of translational medicine [Ann Transl Med] 2021 Feb; Vol. 9 (3), pp. 218.