Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Dionzie Ong"'
Autor:
Xianbing Zhu, Zheng Fu, Shary Y. Chen, Dionzie Ong, Giulio Aceto, Rebecca Ho, Jutta Steinberger, Anie Monast, Virginie Pilon, Eunice Li, Monica Ta, Kyle Ching, Bianca N. Adams, Gian L. Negri, Luc Choiniere, Lili Fu, Kitty Pavlakis, Patrick Pirrotte, Daina Z. Avizonis, Jeffrey Trent, Bernard E. Weissman, Ramon I. Klein Geltink, Gregg B. Morin, Morag Park, David G. Huntsman, William D. Foulkes, Yemin Wang, Sidong Huang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract SMARCA4 (BRG1) and SMARCA2 (BRM) are the two paralogous ATPases of the SWI/SNF chromatin remodeling complexes frequently inactivated in cancers. Cells deficient in either ATPase have been shown to depend on the remaining counterpart for surv
Externí odkaz:
https://doaj.org/article/9b0a23025ed145939844545536f59b3f
Autor:
Xianbing Zhu, Zheng Fu, Shary Chen, Dionzie Ong, Giulio Aceto, Rebecca Ho, Jutta Steinberger, Eunice Li, David Huntsman, William Foulkes, Sidong Huang, Yemin Wang
Publikováno v:
Cancer Research. 83:3671-3671
SMARCA4 (BRG1) and SMARCA2 (BRM) are the two paralogous ATPases of the SWI/SNF chromatin remodelling complexes. These two ATPases are frequently inactivated in cancers and cancer cells deficient in either of them have been shown to depend on the rema
Autor:
Shuai Wu, Rugang Zhang, Nail Fatkhutdinov, Andrew V. Kossenkov, David W. Speicher, Zachary T. Schug, Heng Liu, Yemin Wang, Sergey Karakashev, Dionzie Ong, Ronny Drapkin, Lauren E. Schwartz, Timothy Nacarelli, Hsin-Yao Tang, Takeshi Fukumoto, Wei Zhou, Chi V. Dang, David G. Huntsman, Jianhuang Lin, Joseph A. Zundell, Qin Liu
Publikováno v:
Nat Cancer
Alterations in components of the SWI/SNF chromatin-remodeling complex occur in ~20% of all human cancers. For example, ARID1A is mutated in up to 62% of clear cell ovarian carcinoma (OCCC), a disease currently lacking effective therapies. Here we sho
Autor:
Eunice Li, Bernard E. Weissman, Patrick Pirrotte, Dionzie Ong, Krystal A. Orlando, Yemin Wang, David Humtsman, Shary Yuting Chen, Jennifer X Ji, Elizabeth A. Raupach
Publikováno v:
Cancer Research. 80:1459-1459
Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) and dedifferentiated carcinoma of the ovary or endometrium are rare but highly aggressive types of gynecologic cancers. We and others have recently demonstrated that genetic inactivation