Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Dionysia Dimitrakopoulou"'
Autor:
Nicholas James Miller, Dionysia Dimitrakopoulou, Laurel A. Baglia, Martin S. Pavelka, Jacques Robert
Publikováno v:
Microorganisms, Vol 12, Iss 6, p 1120 (2024)
Mycobacterium abscessus (Mab) is an emerging human pathogen that has a high rate of incidence in immunocompromised individuals. We have found a putative secondary metabolite pathway within Mab, which may be a key factor in its pathogenesis. This nove
Externí odkaz:
https://doaj.org/article/edb662adb1ef4d8eaf38adb53f69b912
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/619f80e91a9c4aceab1e6f5274429938
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Aquatic vertebrate organisms such as zebrafish have been used for over a decade to model different types of human cancer, including hematologic malignancies. However, the introduction of gene editing techniques such as CRISPR/Cas9 and TALEN, have now
Externí odkaz:
https://doaj.org/article/e58bf138babe404abca62abe6c83f2e0
Autor:
Arianna Lopez, Carolyn Shoen, Michael Cynamon, Dionysia Dimitrakopoulou, Matthieu Paiola, Martin S. Pavelka, Jacques Robert
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2, p 806 (2021)
Mycobacterium abscessus (Mab) is an emerging, nontuberculosis mycobacterium (NTM) that infects humans. Mab has two morphotypes, smooth (S) and rough (R), related to the production of glycopeptidolipid (GPL), that differ in pathogenesis. To further un
Externí odkaz:
https://doaj.org/article/a59756b810da484ab17756c712bf28da
Autor:
Cornelis J. van Noorden, Fonnet E. Bleeker, William P. Leenders, W. Peter Vandertop, Jaroslaw P. Maciejewski, Johanna W. Wilmink, Tomas Radivoyevitch, Ron A. Hoebe, Cornelis M. van Drunen, Dionysia Dimitrakopoulou, Adri N. Mul, Krissie Lenting, Mohammed Khurshed, Peter Henneman, Jan Stap, Sanne A. van Lith, Vashendriya V. Hira, Myrthe A. Smits, Dennis Botman, Remco J. Molenaar
D-2HG inhibits IDH-mediated NADPH production capacity, but not G6PD-mediated NADPH production capacity or IDH-mediated NADH production capacity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c00fef62eafc6548de46176770adc97
https://doi.org/10.1158/0008-5472.22412280.v1
https://doi.org/10.1158/0008-5472.22412280.v1
Autor:
Cornelis J. van Noorden, Fonnet E. Bleeker, William P. Leenders, W. Peter Vandertop, Jaroslaw P. Maciejewski, Johanna W. Wilmink, Tomas Radivoyevitch, Ron A. Hoebe, Cornelis M. van Drunen, Dionysia Dimitrakopoulou, Adri N. Mul, Krissie Lenting, Mohammed Khurshed, Peter Henneman, Jan Stap, Sanne A. van Lith, Vashendriya V. Hira, Myrthe A. Smits, Dennis Botman, Remco J. Molenaar
SPSS output statistics for comparisons between survival curves from colony-formation assays.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20d1222c3980f828fe4ee1f14a765f79
https://doi.org/10.1158/0008-5472.22412268.v1
https://doi.org/10.1158/0008-5472.22412268.v1
Autor:
Cornelis J. van Noorden, Fonnet E. Bleeker, William P. Leenders, W. Peter Vandertop, Jaroslaw P. Maciejewski, Johanna W. Wilmink, Tomas Radivoyevitch, Ron A. Hoebe, Cornelis M. van Drunen, Dionysia Dimitrakopoulou, Adri N. Mul, Krissie Lenting, Mohammed Khurshed, Peter Henneman, Jan Stap, Sanne A. van Lith, Vashendriya V. Hira, Myrthe A. Smits, Dennis Botman, Remco J. Molenaar
Isocitrate dehydrogenase 1 (IDH1) is mutated in various types of human cancer to IDH1R132H, a structural alteration that leads to catalysis of α-ketoglutarate to the oncometabolite D-2-hydroxyglutarate. In this study, we present evidence that small-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5c1fa1f1ef7af279dc9e5e587d4809e
https://doi.org/10.1158/0008-5472.c.6508407.v1
https://doi.org/10.1158/0008-5472.c.6508407.v1
Autor:
Dionysia Dimitrakopoulou, Collins N. Khwatenge, Christina James-Zorn, Matthieu Paiola, Eleanor Wise Bellin, Yun Tian, Nivitha Sundararaj, Emma J. Polak, Leon Grayfer, Daron Barnard, Yuko Ohta, Marko Horb, Yongming Sang, Jacques Robert
Publikováno v:
Developmental & Comparative Immunology. 145:104734
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c245b8f6052239a045f2716c28a7a0b2
https://doi.org/10.1016/j.dci.2023.104734
https://doi.org/10.1016/j.dci.2023.104734
Autor:
Dieter, Tulkens, Dionysia, Dimitrakopoulou, Marthe, Boelens, Tom, Van Nieuwenhuysen, Suzan, Demuynck, Wendy, Toussaint, David, Creytens, Pieter, Van Vlierberghe, Kris, Vleminckx
Publikováno v:
Cancers. 14(19)
Modeling human genetic diseases and cancer in lab animals has been greatly aided by the emergence of genetic engineering tools such as TALENs and CRISPR/Cas9. We have previously demonstrated the ease with which genetically engineered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ab72b7ffafb760f2baf667363ad3f76c
https://pubmed.ncbi.nlm.nih.gov/36230482
https://pubmed.ncbi.nlm.nih.gov/36230482
Publikováno v:
Developmental & Comparative Immunology. 139:104594
Mycobacterial infections represent major concerns for aquatic and terrestrial vertebrates including humans. Although our current knowledge is mostly restricted to Mycobacterium tuberculosis and mammalian host interactions, increasing evidence suggest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::241a10c6212040f0f7b83a8a63e73a7a
https://doi.org/10.1016/j.dci.2022.104594
https://doi.org/10.1016/j.dci.2022.104594