Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Dionne Vafeados"'
Autor:
Nathaniel R. Bennett, Brian Coventry, Inna Goreshnik, Buwei Huang, Aza Allen, Dionne Vafeados, Ying Po Peng, Justas Dauparas, Minkyung Baek, Lance Stewart, Frank DiMaio, Steven De Munck, Savvas N. Savvides, David Baker
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract Recently it has become possible to de novo design high affinity protein binding proteins from target structural information alone. There is, however, considerable room for improvement as the overall design success rate is low. Here, we explo
Externí odkaz:
https://doaj.org/article/279adbbdbddf4e41bbd9f4a899f986cf
Autor:
Nathaniel Bennett, Brian Coventry, Inna Goreshnik, Buwei Huang, Aza Allen, Dionne Vafeados, Ying Po Peng, Justas Dauparas, Minkyung Baek, Lance Stewart, Frank DiMaio, Steven De Munck, Savvas N. Savvides, David Baker
We explore the improvement of energy-based protein binder design using deep learning. We find that using AlphaFold2 or RoseTTAFold to assess the probability that a designed sequence adopts the designed monomer structure, and the probability that this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67ef1ed5128106ab6a3f74277fb56334
https://doi.org/10.1101/2022.06.15.495993
https://doi.org/10.1101/2022.06.15.495993
Autor:
Michelle M, Kudron, Alec, Victorsen, Louis, Gevirtzman, LaDeana W, Hillier, William W, Fisher, Dionne, Vafeados, Matt, Kirkey, Ann S, Hammonds, Jeffery, Gersch, Haneen, Ammouri, Martha L, Wall, Jennifer, Moran, David, Steffen, Matt, Szynkarek, Samantha, Seabrook-Sturgis, Nader, Jameel, Madhura, Kadaba, Jaeda, Patton, Robert, Terrell, Mitch, Corson, Timothy J, Durham, Soo, Park, Swapna, Samanta, Mei, Han, Jinrui, Xu, Koon-Kiu, Yan, Susan E, Celniker, Kevin P, White, Lijia, Ma, Mark, Gerstein, Valerie, Reinke, Robert H, Waterston
Publikováno v:
Genetics. 208(3)
To develop a catalog of regulatory sites in two major model organisms, Drosophila melanogaster and Caenorhabditis elegans, the modERN (model organism Encyclopedia of Regulatory Networks) consortium has systematically assayed the binding sites of tran
Autor:
Jun-Xian He, Shigeo Yoshida, Shozo Fujioka, Joshua M. Gendron, Takeshi Nakano, Zhi-Yong Wang, Yanli Yang, Tadao Asami, Dionne Vafeados, Meng Chen, Joanne Chory
Publikováno v:
Developmental Cell. 2(4):505-513
Plant steroid hormones, brassinosteroids (BRs), are perceived by a cell surface receptor kinase, BRI1, but how BR binding leads to regulation of gene expression in the nucleus is unknown. Here we describe the identification of BZR1 as a nuclear compo
Autor:
Sarah P. Chu, Roger Y. Tsien, Andrea Kemper, Gary Tallman, Chad T. Shimazaki, Julian I. Schroeder, Gethyn J. Allen, Scott D. Hawke, Joanne Chory, Karin Schumacher, Jeffrey F. Harper, Dionne Vafeados
Publikováno v:
Science. 289:2338-2342
Cytosolic calcium oscillations control signaling in animal cells, whereas in plants their importance remains largely unknown. In wild-type Arabidopsis guard cells abscisic acid, oxidative stress, cold, and external calcium elicited cytosolic calcium
Publikováno v:
Genes & Development. 13:3259-3270
During the development of multicellular organisms, an intricate coordination of cell division and cell enlargement is necessary to achieve both morphogenesis and growth. In contrast to our rapidly growing knowledge of pattern formation and morphogene
Autor:
Joanne A. Labate, Silvana Grandillo, Theresa Fulton, Stéphane Muños, Ana L. Caicedo, Iris Peralta, Yuanfu Ji, Roger T. Chetelat, J. W. Scott, Maria Jose Gonzalo, David Francis, Wencai Yang, Esther van der Knaap, Angela M. Baldo, Brian Smith-White, Lukas A. Mueller, James P. Prince, Nicholas E. Blanchard, Dylan B. Storey, Mikel R. Stevens, Matthew D. Robbins, Jaw-Fen Wang, Barbara E. Liedl, Mary A. O’Connell, John R. Stommel, Koh Aoki, Yoko Iijima, Ann J. Slade, Susan R. Hurst, Dayna Loeffler, Michael N. Steine, Dionne Vafeados, Cate McGuire, Carrie Freeman, Anna Amen, John Goodstal, Daniel Facciotti, Joyce Van Eck, Mathilde Causse
Publikováno v:
Vegetables ISBN: 9783540345350
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fb0630e0c886a6c196ad6d31eaf7414
https://doi.org/10.1007/978-3-540-34536-7_1
https://doi.org/10.1007/978-3-540-34536-7_1
Autor:
Yanhai Yin, Jin-Chen Cheng, Ana I. Caño-Delgado, Dionne Vafeados, Joanne Chory, Kyoung Hee Nam, Cong Yu, Jianming Li, Santiago Mora-García
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Plant steroid hormones, brassinosteroids (BRs), are perceived by the plasma membrane-localized leucine-rich-repeat-receptor kinase BRI1. Based on sequence similarity, we have identified three members of the BRI1 family, named BRL1, BRL2 and BRL3. BRL
Publikováno v:
Plant physiology. 127(1)
Brassinosteroids (BRs) play important roles throughout plant development. Although many genes have been identified that are involved in BR biosynthesis, genetic approaches in Arabidopsis have led to the identification of only one gene, BRI1, that enc
Publikováno v:
Cell. (2):249-259
Brassinosteroids (BRs) signal through a plasma membrane-localized receptor kinase to regulate plant growth and development. We showed previously that a novel protein, BES1, accumulates in the nucleus in response to BRs, where it plays a role in BR-re