Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Dionisios Rentzeperis"'
Autor:
Hossein B. Askari, Raymond J. Patch, Wing S. Cheung, Hui Huang, Derek A. Beauchamp, Jyotsna Kasturi, Meghan Towers, Jianying Liu, Bao-Ping Zhao, Sharmila Patel, Dionisios Rentzeperis, Micheal Gaul, Mark R. Player, Guozhang Xu, John G. Geisler
Publikováno v:
European Journal of Medicinal Chemistry. 138:830-853
Estrogen-related receptor α (ERRα) is an orphan nuclear receptor that has been functionally implicated in the regulation of energy homeostasis. Herein is described the development of indazole-based N-alkylthiazolidenediones, which function in bioch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdb5c376454ed13376d112e16a0c3b4e
https://doi.org/10.1016/j.ejmech.2017.07.015
https://doi.org/10.1016/j.ejmech.2017.07.015
Autor:
Cynthia Milligan, Hossein Askari, Marta C. Abad, Frank Lewandowski, Barry A. Springer, John C. O’Neill, John C. Spurlino, Dionisios Rentzeperis, Alexandra L. Klinger
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 108:44-54
We screened the ligand-binding domain of estrogen-related receptor (ERR) gamma in ThermoFluor, in an effort to develop chemical tools and decipher the biology of this orphan nuclear receptor. Several ligands were found to stabilize thermodynamically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e88599e3c028d2d97ac097651dcda716
https://doi.org/10.1016/j.jsbmb.2007.06.006
https://doi.org/10.1016/j.jsbmb.2007.06.006
Publikováno v:
The Journal of Physical Chemistry B. 106:9945-9950
DNA intramolecular hairpins are appropriate models for the thermodynamic description of the pseudo-intramolecular melting behavior of native DNA. To improve our understanding of the stability and melting behavior of DNA secondary structures and of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea950037ebe18e56f30f890794a5d532
https://doi.org/10.1021/jp0260853
https://doi.org/10.1021/jp0260853
Publikováno v:
Nature Structural Biology. 6:569-573
The refolding rate of the Arc repressor dimer can be accelerated 30-fold or more by negatively charged polymers including single-stranded and double-stranded DNA, RNA, and polyvinylsulfate but not by neutral or positively charged polymers. The salt-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78a78c7800440c4ec63f97abf43b6137
https://doi.org/10.1038/9353
https://doi.org/10.1038/9353
Publikováno v:
Journal of Molecular Biology. 273:692-700
The thermal stability of the Arc repressor dimer normally increases with concentration because protein folding and subunit association are thermodynamically coupled. At Arc concentrations above 100 μM, however, thermal denaturation remains reversibl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42ef5a09455987d6f62e71dcbbeec273
https://doi.org/10.1006/jmbi.1997.1342
https://doi.org/10.1006/jmbi.1997.1342
Autor:
Nicholas E. Geacintov, Luis A. Marky, Monique Cosman, Nataly P. Luneva, Dionisios Rentzeperis, Donald W. Kupke
Publikováno v:
Journal of the American Chemical Society. 118:3804-3810
A combination of UV spectroscopy, calorimetry, and density techniques were used to characterize the thermodynamics of complexes with covalently bound hydrophobic pyrenyl residues in the minor groove of DNA undecamer duplexes. The control duplex d(CCA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::339683e59057cd6cc7f174ac7f8813da
https://doi.org/10.1021/ja9538703
https://doi.org/10.1021/ja9538703
Publikováno v:
Journal of the American Chemical Society. 116:9423-9429
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9161236031524601bc62272f38a6b1ac
https://doi.org/10.1021/ja00100a003
https://doi.org/10.1021/ja00100a003
Autor:
John G. Geisler, Lily Lee Searle, Hossein Askari, Debyendu De, John O’Neill, Michael Kemmerer, James M Lenhard, Jianying Liu, Ling Lin, Xizhen Zhu, Marta C. Abad, Jyotsna Kasturi, Micheal Gaul, Raymond J. Patch, Dionisios Rentzeperis, Mark R. Player, Alexander Kim
Publikováno v:
Journal of medicinal chemistry. 54(3)
Estrogen-related receptor α (ERRα) is an orphan nuclear receptor that has been functionally implicated in the regulation of energy homeostasis. Herein is described the development of diaryl ether based thiazolidenediones, which function as selectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b60672295f1eee8d6b63f3dd787717b
https://pubmed.ncbi.nlm.nih.gov/21218783
https://pubmed.ncbi.nlm.nih.gov/21218783
Autor:
Luis A. Marky, Dionisios Rentzeperis
Publikováno v:
Journal of the American Chemical Society. 115:1645-1650
We use the minor groove ligand netropsin as a thermodynamic probe of the grooves of parallel DNA. A combination of circular dichroism spectroscopy, temperature-dependent UV spectroscopy, and isothermal titration calorimetry has been employed to chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36bbb2a2d41177a1921afe032a020d7d
https://doi.org/10.1021/ja00058a005
https://doi.org/10.1021/ja00058a005
Publikováno v:
Biopolymers. 32:1065-1075
The minor groove ligand distamycin A has been used to probe the relative hydration of the minor groove of eight synthetic polynucleotides of known sequence and composition. A combination of densimetric, calorimetric, and temperature-dependent spectro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89b51c7fd204f18768f7ab01482e2b14
https://doi.org/10.1002/bip.360320816
https://doi.org/10.1002/bip.360320816