Výsledky vyhledávání - "Dion Legemaate"

The Antiviral Agent Cidofovir Induces DNA Damage and Mitotic Catastrophe in HPV-Positive and -Negative Head and Neck Squamous Cell Carcinomas In Vitro

Autor: Ernst-Jan M. Speel, Imke Demers, Bernd Kremer, Dion Legemaate, Wisse Evert Haakma, Robin Jacobs, Femke Verhees, Mat Rousch

Publikováno v: Cancers, Vol 11, Iss 7, p 919 (2019)
Cancers
Volume 11
Issue 7
Cancers, 11(7):919. Multidisciplinary Digital Publishing Institute (MDPI)

Cidofovir (CDV) is an antiviral agent with antiproliferative properties. The aim of our study was to investigate the efficacy of CDV in HPV-positive and -negative head and neck squamous cell carcinoma (HNSCC) cell lines and whether it is caused by a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e95ad8aac3847dc6c4c063dbca751a7
https://www.mdpi.com/2072-6694/11/7/919

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Abstract 2969: The antiviral agent Cidofovir induces DNA damage and mitotic catastrophe in HPV-positive and -negative head and neck squamous cell carcinomas in vitro

Autor: Ernst-Jan M. Speel, Femke Verhees, Dion Legemaate, Robin Jacobs, Wisse E. Haakma, Mat Rousch, Bernd Kremer

Publikováno v: Cancer Research. 79:2969-2969

Objectives: Cidofovir (CDV) is an antiviral agent with anti-proliferative properties and is suggested as treatment option in head and neck squamous cell carcinoma (HNSCC) patients to improve outcome and quality of life. The mechanisms underlying the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::08645f0bfeda6ba9c2c9c2f8e8b12eb8
https://doi.org/10.1158/1538-7445.am2019-2969

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