Výsledky vyhledávání - "Diogo M. Lourenço"

Akademický článek

Neural Stem Cells and Cannabinoids in the Spotlight as Potential Therapy for Epilepsy

Autor: Diogo M. Lourenço, Leonor Ribeiro-Rodrigues, Ana M. Sebastião, Maria J. Diógenes, Sara Xapelli

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 19, p 7309 (2020)

Epilepsy is one of the most common brain diseases worldwide, having a huge burden in society. The main hallmark of epilepsy is the occurrence of spontaneous recurrent seizures, having a tremendous impact on the lives of the patients and of their rela

Externí odkaz: https://doaj.org/article/f9ceecc4cf0f48cb84fe5e6871f7c568

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Akademický článek

Cannabinoid Actions on Neural Stem Cells: Implications for Pathophysiology

Autor: Rui S. Rodrigues, Diogo M. Lourenço, Sara L. Paulo, Joana M. Mateus, Miguel F. Ferreira, Francisco M. Mouro, João B. Moreira, Filipa F. Ribeiro, Ana M. Sebastião, Sara Xapelli

Publikováno v: Molecules, Vol 24, Iss 7, p 1350 (2019)

With the increase of life expectancy, neurodegenerative disorders are becoming not only a health but also a social burden worldwide. However, due to the multitude of pathophysiological disease states, current treatments fail to meet the desired outco

Externí odkaz: https://doaj.org/article/0d48ce5ecb2b492c99ff1ec4799cabea

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Akademický článek

The neurosphere assay: an effective in vitro technique to study neural stem cells

Autor: Rita Soares, Filipa F Ribeiro, Diogo M Lourenço, Rui S Rodrigues, João B Moreira, Ana M Sebastião, Vanessa A Morais, Sara Xapelli

Publikováno v: Neural Regeneration Research, Vol 16, Iss 11, Pp 2229-2231 (2021)

Externí odkaz: https://doaj.org/article/51ef509e7e954bad841c22f73d0beeee

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Unravelling a novel role for Cannabidivarin in the modulation of subventricular zone postnatal neurogenesis

Autor: Diogo M. Lourenço, Rita Soares, Sónia Sá Santos, Joana M. Mateus, Rui S. Rodrigues, João B. Moreira, Sandra H. Vaz, Ana M. Sebastião, Susana Solá, Sara Xapelli

Postnatal neurogenesis has been shown to rely on the endocannabinoid system. Here we aimed at unravelling the role of Cannabidivarin (CBDV), a non-psychoactive cannabinoid, with high affinity for the non-classical cannabinoid receptor TRPV1, on subve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::80ea7d7af1e400cfbaf7e2a5d413a597
https://doi.org/10.1101/2023.05.16.540990

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Neural stem cells and cannabinoids in the spotlight as potential therapy for epilepsy

Autor: Ana M. Sebastião, Leonor Ribeiro-Rodrigues, Sara Xapelli, Maria José Diógenes, Diogo M Lourenço

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
International Journal of Molecular Sciences, Vol 21, Iss 7309, p 7309 (2020)
International Journal of Molecular Sciences

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Epile

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2ed58e8508574bc572280e1a4baa23d
https://hdl.handle.net/10451/47351

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Mitochondrial Dynamics: impact on adult neural stem cell fate

Autor: Vanessa Alexandra Morais, Rita Soares, Ana M. Sebastião, Jonathan Verduyckt, Diogo M Lourenço, Sara Xapelli

Neural stem cells (NSCs) are found in discrete regions of the mammalian brain. During adulthood, NSCs can be a source of new neurons and oligodendrocytes in neurological disorders. However, these newborn cells are not sufficient to overcome the neuro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3e1504cfeb6ce8c68984e9e26c5802f8
https://doi.org/10.14293/s2199-1006.1.sor-.ppvi8us.v1

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Not just nociception: regulation of postnatal neurogenesis by TRPV1

Autor: Rita Soares, Ana Morais Sebastião, Rui S Rodrigues, Sara Xapelli, Diogo M Lourenço

The Endocannabinoid System has been shown to play a pivotal role in different neurogenic stages, namely in differentiation and maturation of postnatal neural stem/progenitor cells (NSPC) mainly via the activation of the classical cannabinoid receptor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6d3dc8a7e94b84e9ef65e4a45772663d
https://doi.org/10.14293/s2199-1006.1.sor-.ppbbxoh.v1

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Isolation and Expansion of Neurospheres from Postnatal (P1-3) Mouse Neurogenic Niches

Autor: Rita, Soares, Filipa F, Ribeiro, Diogo M, Lourenço, Rui S, Rodrigues, João B, Moreira, Ana M, Sebastião, Vanessa A, Morais, Sara, Xapelli

Publikováno v: Journal of visualized experiments : JoVE. (159)

The neurosphere assay is an extremely useful in vitro technique for studying the inherent properties of neural stem/progenitor cells (NSPCs) including proliferation, self-renewal and multipotency. In the postnatal and adult brain, NSPCs are mainly pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ff61851d23b9d7dc4cea8bb2fd5435ac
https://pubmed.ncbi.nlm.nih.gov/32510488

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