Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Diogo M Ribeiro"'
Autor:
Anna V Protasio, Stijn van Dongen, Julie Collins, Leonor Quintais, Diogo M Ribeiro, Florian Sessler, Martin Hunt, Gabriel Rinaldi, James J Collins, Anton J Enright, Matthew Berriman
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 6, p e0010521 (2022)
[This corrects the article DOI: 10.1371/journal.pntd.0005559.].
Externí odkaz:
https://doaj.org/article/2abf1215da0f4155b1c6fef149bb3ed0
Autor:
Anna V Protasio, Stijn van Dongen, Julie Collins, Leonor Quintais, Diogo M Ribeiro, Florian Sessler, Martin Hunt, Gabriel Rinaldi, James J Collins, Anton J Enright, Matthew Berriman
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 5, p e0005559 (2017)
Schistosomes are parasitic helminths that cause schistosomiasis, a disease affecting circa 200 million people, primarily in underprivileged regions of the world. Schistosoma mansoni is the most experimentally tractable schistosome species due to its
Externí odkaz:
https://doaj.org/article/ce4a46a4e17845d2ae8631c284919f64
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
Using single-cell data from cell lines, the co-expression of genes and co-activity of regulatory elements is analyzed, providing insight into shared architecture and regulation between genes.
Externí odkaz:
https://doaj.org/article/c84b92fd8c254b43a4273788374f3fc9
Multimodal single cell analysis infers widespread enhancer co-activity in a lymphoblastoid cell line
Publikováno v:
Communications Biology. 6
Non-coding regulatory elements such as enhancers are key in controlling the cell-type specificity and spatio-temporal expression of genes. To drive stable and precise gene transcription robust to genetic variation and environmental stress, genes are
Autor:
Diana Avalos, Guillaume Rey, Diogo M. Ribeiro, Anna Ramisch, Emmanouil T. Dermitzakis, Olivier Delaneau
Publikováno v:
Communications Biology. 6
Studying the interplay between genetic variation, epigenetic changes, and regulation of gene expression is crucial to understand the modification of cellular states in various conditions, including immune diseases. In this study, we characterize the
The UK Biobank performed whole-genome sequencing (WGS) and whole-exome sequencing (WES) across hundreds of thousands of individuals, allowing researchers to study the effects of both common and rare variants. Haplotype phasing distinguishes the two i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1d98aa3f1eec3538cb034c523eb0771
https://doi.org/10.1101/2022.10.19.512867
https://doi.org/10.1101/2022.10.19.512867
Autor:
Diana Avalos, Guillaume Rey, Diogo M. Ribeiro, Anna Ramisch, Emmanouil Dermitzakis, Olivier Delaneau
Studying the interplay between genetic variation, epigenetic changes and regulation of gene expression in immune cells is important to understand the modification of cellular states in various conditions, including immune diseases. Here, we built cis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17b6bd416f345bd34cccd785be3cae9e
https://doi.org/10.21203/rs.3.rs-1897960/v1
https://doi.org/10.21203/rs.3.rs-1897960/v1
Publikováno v:
Nature Genetics. 53:120-126
Low-coverage whole-genome sequencing followed by imputation has been proposed as a cost-effective genotyping approach for disease and population genetics studies. However, its competitiveness against SNP arrays is undermined because current imputatio
Autor:
Robin J, Hofmeister, Simone, Rubinacci, Diogo M, Ribeiro, Alfonso, Buil, Zoltán, Kutalik, Olivier, Delaneau
Publikováno v:
Nature communications. 13(1)
Identical genetic variations can have different phenotypic effects depending on their parent of origin. Yet, studies focusing on parent-of-origin effects have been limited in terms of sample size due to the lack of parental genomes or known genealogi
Publikováno v:
bioRxiv
BioRxiv (preprint server)
BioRxiv (preprint server)
Most human genes are co-expressed with a nearby gene. Previous studies have revealed this local gene co-expression to be widespread across chromosomes and across dozens of tissues. Yet, so far these studies used bulk RNA-seq, averaging gene expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be52e804f529466e73650b73664ffb1d
https://doi.org/10.1101/2021.12.14.472573
https://doi.org/10.1101/2021.12.14.472573