Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Diogo, Meyer"'
Autor:
Michel S. Naslavsky, Marilia O. Scliar, Guilherme L. Yamamoto, Jaqueline Yu Ting Wang, Stepanka Zverinova, Tatiana Karp, Kelly Nunes, José Ricardo Magliocco Ceroni, Diego Lima de Carvalho, Carlos Eduardo da Silva Simões, Daniel Bozoklian, Ricardo Nonaka, Nayane dos Santos Brito Silva, Andreia da Silva Souza, Heloísa de Souza Andrade, Marília Rodrigues Silva Passos, Camila Ferreira Bannwart Castro, Celso T. Mendes-Junior, Rafael L. V. Mercuri, Thiago L. A. Miller, Jose Leonel Buzzo, Fernanda O. Rego, Nathalia M. Araújo, Wagner C. S. Magalhães, Regina Célia Mingroni-Netto, Victor Borda, Heinner Guio, Carlos P. Rojas, Cesar Sanchez, Omar Caceres, Michael Dean, Mauricio L. Barreto, Maria Fernanda Lima-Costa, Bernardo L. Horta, Eduardo Tarazona-Santos, Diogo Meyer, Pedro A. F. Galante, Victor Guryev, Erick C. Castelli, Yeda A. O. Duarte, Maria Rita Passos-Bueno, Mayana Zatz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Whole genome sequencing (WGS) data on non-European and admixed individuals remains scarce. Here, the authors analyse WGS data from 1,171 admixed elderly Brazilians from a census cohort, characterising population-specific genetic variation and explori
Externí odkaz:
https://doaj.org/article/363cefb9d1d14e1f9adc1fe81f04cd3f
Autor:
Erick C. Castelli, Mateus V. de Castro, Michel S. Naslavsky, Marilia O. Scliar, Nayane S. B. Silva, Raphaela N. Pereira, Viviane A. O. Ciriaco, Camila F. B. Castro, Celso T. Mendes-Junior, Etiele de S. Silveira, Iuri M. de Oliveira, Eduardo C. Antonio, Gustavo F. Vieira, Diogo Meyer, Kelly Nunes, Larissa R. B. Matos, Monize V. R. Silva, Jaqueline Y. T. Wang, Joyce Esposito, Vivian R. Cória, Jhosiene Y. Magawa, Keity S. Santos, Edecio Cunha-Neto, Jorge Kalil, Raul H. Bortolin, Mário Hiroyuki Hirata, Luiz P. Dell’Aquila, Alvaro Razuk-Filho, Pedro B. Batista-Júnior, Amaro N. Duarte-Neto, Marisa Dolhnikoff, Paulo H. N. Saldiva, Maria Rita Passos-Bueno, Mayana Zatz
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundAlthough aging correlates with a worse prognosis for Covid-19, super elderly still unvaccinated individuals presenting mild or no symptoms have been reported worldwide. Most of the reported genetic variants responsible for increased disease
Externí odkaz:
https://doaj.org/article/2e2117d94dbe4d5a98250112d4b97251
Autor:
Erick C. Castelli, Mateus V. de Castro, Michel S. Naslavsky, Marilia O. Scliar, Nayane S. B. Silva, Heloisa S. Andrade, Andreia S. Souza, Raphaela N. Pereira, Camila F. B. Castro, Celso T. Mendes-Junior, Diogo Meyer, Kelly Nunes, Larissa R. B. Matos, Monize V. R. Silva, Jaqueline Y. T. Wang, Joyce Esposito, Vivian R. Coria, Raul H. Bortolin, Mario H. Hirata, Jhosiene Y. Magawa, Edecio Cunha-Neto, Verônica Coelho, Keity S. Santos, Maria Lucia C. Marin, Jorge Kalil, Miguel Mitne-Neto, Rui M. B. Maciel, Maria Rita Passos-Bueno, Mayana Zatz
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Despite the high number of individuals infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) who develop coronavirus disease 2019 (COVID-19) symptoms worldwide, many exposed individuals remain asymptomatic and/or uninfected and ser
Externí odkaz:
https://doaj.org/article/e2fb2fd00c7a451aa7e883d2e932e816
Autor:
Ohanna Cavalcanti de Lima Bezerra, Lucia Elena Alvarado-Arnez, Nédio Mabunda, Graça Salomé, Amina de Sousa, Fernanda de Souza Gomes Kehdy, Carolinne Sales-Marques, Fernanda Saloum de Neves Manta, Rafaela Mota Andrade, Laís Pereira Ferreira, Thyago Leal-Calvo, Cynthia Chester Cardoso, Kelly Nunes, Mateus H Gouveia, Sam M Mbulaiteve, Edward D Yeboah, Ann Hsing, Ana Carla Pereira Latini, André Luiz Leturiondo, Fabíola da Costa Rodrigues, Ariani Batista Noronha, Cynthia de Oliveira Ferreira, Carolina Talhari, Jamile Leão Rêgo, Léa Cristina de Carvalho Castellucci, Eduardo Tarazona-Santos, Elizeu Fagundes de Carvalho, Diogo Meyer, Roberta Olmo Pinheiro, Ilesh V Jani, Antonio Guilherme Pacheco, Milton Ozório Moraes
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 8, p e0009434 (2021)
Pyruvate kinase (PK), encoded by the PKLR gene, is a key player in glycolysis controlling the integrity of erythrocytes. Due to Plasmodium selection, mutations for PK deficiency, which leads to hemolytic anemia, are associated with resistance to mala
Externí odkaz:
https://doaj.org/article/27f786c7db174a1b9892efcd1ad0d8da
Autor:
Vitor R. C. Aguiar, Danillo G. Augusto, Erick C. Castelli, Jill A. Hollenbach, Diogo Meyer, Kelly Nunes, Maria Luiza Petzl-Erler
Publikováno v:
Genetics and Molecular Biology, Vol 44, Iss 1 suppl 1 (2021)
Abstract Meeting the challenges brought by the COVID-19 pandemic requires an interdisciplinary approach. In this context, integrating knowledge of immune function with an understanding of how genetic variation influences the nature of immunity is a k
Externí odkaz:
https://doaj.org/article/dfb43c8b79404c4d93935ceb43a680b4
Autor:
Kelly Nunes, Vitor R. C. Aguiar, Márcio Silva, Alexandre C. Sena, Danielli C. M. de Oliveira, Carla L. Dinardo, Fernanda S. G. Kehdy, Eduardo Tarazona-Santos, Vanderson G. Rocha, Anna Barbara F. Carneiro-Proietti, Paula Loureiro, Miriam V. Flor-Park, Claudia Maximo, Shannon Kelly, Brian Custer, Bruce S. Weir, Ester C. Sabino, Luís Cristóvão Porto, Diogo Meyer
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
A match of HLA loci between patients and donors is critical for successful hematopoietic stem cell transplantation. However, the extreme polymorphism of HLA loci – an outcome of millions of years of natural selection – reduces the chances that tw
Externí odkaz:
https://doaj.org/article/7135c23b854d4ea48891ccb520ebe641
Autor:
Michel S. Naslavsky, Marilia O. Scliar, Guilherme L. Yamamoto, Jaqueline Yu Ting Wang, Stepanka Zverinova, Tatiana Karp, Kelly Nunes, José Ricardo Magliocco Ceroni, Diego Lima de Carvalho, Carlos Eduardo da Silva Simões, Daniel Bozoklian, Ricardo Nonaka, Nayane dos Santos Brito Silva, Andreia da Silva Souza, Heloísa de Souza Andrade, Marília Rodrigues Silva Passos, Camila Ferreira Bannwart Castro, Celso T. Mendes-Junior, Rafael L. V. Mercuri, Thiago L. A. Miller, Jose Leonel Buzzo, Fernanda O. Rego, Nathalia M. Araújo, Wagner C. S. Magalhães, Regina Célia Mingroni-Netto, Victor Borda, Heinner Guio, Carlos P. Rojas, Cesar Sanchez, Omar Caceres, Michael Dean, Mauricio L. Barreto, Maria Fernanda Lima-Costa, Bernardo L. Horta, Eduardo Tarazona-Santos, Diogo Meyer, Pedro A. F. Galante, Victor Guryev, Erick C. Castelli, Yeda A. O. Duarte, Maria Rita Passos-Bueno, Mayana Zatz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/ff914ecb35074c19bb66b71e9811e0de
Autor:
Vitor R. C. Aguiar, Erick C. Castelli, Richard M. Single, Arman Bashirova, Veron Ramsuran, Smita Kulkarni, Danillo G. Augusto, Maureen P. Martin, Maria Gutierrez-Arcelus, Mary Carrington, Diogo Meyer
Publikováno v:
Immunogenetics. 75:249-262
Autor:
Richard M Single, Diogo Meyer, Kelly Nunes, Rodrigo Santos Francisco, Tábita Hünemeier, Martin Maiers, Carolyn K Hurley, Gabriel Bedoya, Carla Gallo, Ana Magdalena Hurtado, Elena Llop, Maria Luiza Petzl-Erler, Giovanni Poletti, Francisco Rothhammer, Luiza Tsuneto, William Klitz, Andrés Ruiz-Linares
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0241282 (2020)
The American continent was the last to be occupied by modern humans, and native populations bear the marks of recent expansions, bottlenecks, natural selection, and population substructure. Here we investigate how this demographic history has shaped
Externí odkaz:
https://doaj.org/article/b409893990874d658745933ef03e82e4
Publikováno v:
PLoS Genetics, Vol 15, Iss 4, p e1008091 (2019)
The HLA (Human Leukocyte Antigens) genes are well-documented targets of balancing selection, and variation at these loci is associated with many disease phenotypes. Variation in expression levels also influences disease susceptibility and resistance,
Externí odkaz:
https://doaj.org/article/8cc2f2ed163a4e40a5ba46b444e3eb30