Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Dinorah Friedmann Morvinski"'
Autor:
Omer Gal, Oshra Betzer, Liat Rousso-Noori, Tamar Sadan, Menachem Motiei, Maxim Nikitin, Dinorah Friedmann-Morvinski, Rachela Popovtzer, Aron Popovtzer
Publikováno v:
Journal of Nanotheranostics, Vol 3, Iss 4, Pp 177-188 (2022)
Background: Glioblastoma is the most lethal primary brain malignancy in adults. Standard of care treatment, consisting of temozolomide (TMZ) and adjuvant radiotherapy (RT), mostly does not prevent local recurrence. The inability of drugs to enter the
Externí odkaz:
https://doaj.org/article/8598e89e65b541529a0ab076d41b71e3
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 1 (2023)
Glioblastoma (GBM) is the most belligerent and frequent brain tumor in adults. Research over the past two decades has provided increased knowledge of the genomic and molecular landscape of GBM and highlighted the presence of a high degree of inter- a
Externí odkaz:
https://doaj.org/article/3a833f48826b44aa929c1cda165df26a
Autor:
Liat Rousso-Noori, Ignacio Mastandrea, Shauli Talmor, Tova Waks, Anat Globerson Levin, Maarja Haugas, Tambet Teesalu, Luis Alvarez-Vallina, Zelig Eshhar, Dinorah Friedmann-Morvinski
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Chimeric antigen receptor (CAR) T cell therapy has been proposed as a promising approach for treating glioblastoma. Here the authors show that p32 is expressed in murine and human glioma and that p32-directed CAR-T cells promote anti-tumor responses
Externí odkaz:
https://doaj.org/article/c9d019d611994e5cb582be3f41cb6a8b
Autor:
Shreoshi Sengupta, Mainak Mondal, Kaval Reddy Prasasvi, Arani Mukherjee, Prerna Magod, Serge Urbach, Dinorah Friedmann-Morvinski, Philippe Marin, Kumaravel Somasundaram
Publikováno v:
eLife, Vol 11 (2022)
Cancer stem cells (CSCs) alone can initiate and maintain tumors, but the function of non-cancer stem cells (non-CSCs) that form the tumor bulk remains poorly understood. Proteomic analysis showed a higher abundance of the extracellular matrix small l
Externí odkaz:
https://doaj.org/article/83f6e89925254fc5a1730338c0dde095
Autor:
Eilam Yeini, Paula Ofek, Sabina Pozzi, Nitzan Albeck, Dikla Ben-Shushan, Galia Tiram, Sapir Golan, Ron Kleiner, Ron Sheinin, Sahar Israeli Dangoor, Shlomit Reich-Zeliger, Rachel Grossman, Zvi Ram, Henry Brem, Thomas M. Hyde, Prerna Magod, Dinorah Friedmann-Morvinski, Asaf Madi, Ronit Satchi-Fainaro
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-22 (2021)
Glioma-associated microglia/macrophages are central drivers of brain tumor pathology. Here the authors characterize the role of the P-selectin/PSGL-1 axis in the cross-talk between glioblastoma cells and microglia/macrophages and show that the therap
Externí odkaz:
https://doaj.org/article/1f79e03ac9e64447af84689d42d725ab
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101106- (2022)
Summary: The immune fraction of the tumor microenvironment has been proven to play a fundamental role in glioblastoma progression and therapeutic response. Here, we present a detailed magnetic-bead-enrichment-based protocol to isolate and analyze the
Externí odkaz:
https://doaj.org/article/427019e28f8e4acb892f73cc157986ae
Autor:
Sankar Jagadeeshan, Manu Prasad, Mai Badarni, Talal Ben-Lulu, Vijayasteltar Belsamma Liju, Sooraj Mathukkada, Claire Saunders, Avital Beeri Shnerb, Jonathan Zorea, Ksenia M. Yegodayev, Monica Wainer, Liza Vtorov, Irit Allon, Ofir Cohen, Gro Gausdal, Dinorah Friedmann-Morvinski, Sok Ching Cheong, Alan L. Ho, Ari J. Rosenberg, Linda Kessler, Francis Burrows, Dexin Kong, Jennifer R. Grandis, J. Silvio Gutkind, Moshe Elkabets
Publikováno v:
Cancer Research. 83:1031-1047
The survival rate for patients with head and neck cancer (HNC) diagnosed with cervical lymph node (cLN) or distant metastasis is low. Genomic alterations in the HRAS oncogene are associated with advanced tumor stage and metastasis in HNC. Elucidation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3b06a1af94f7d5bf2c93656fb854481
https://doi.org/10.1158/0008-5472.can-22-2586
https://doi.org/10.1158/0008-5472.can-22-2586
Autor:
Moshe Elkabets, J. Silvio Gutkind, Jennifer R. Grandis, Dexin Kong, Francis Burrows, Linda Kessler, Ari J. Rosenberg, Alan L. Ho, Sok Ching Cheong, Dinorah Friedmann-Morvinski, Gro Gausdal, Ofir Cohen, Irit Allon, Liza Vtorov, Monica Wainer, Ksenia M. Yegodayev, Jonathan Zorea, Avital Beeri Shnerb, Claire Saunders, Sooraj Mathukkada, Vijayasteltar Belsamma Liju, Talal Ben-Lulu, Mai Badarni, Manu Prasad, Sankar Jagadeeshan
Supplementary Figures S1 to S6 with figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf3a403322c503337cd547d6096d80d2
https://doi.org/10.1158/0008-5472.22549775.v1
https://doi.org/10.1158/0008-5472.22549775.v1
Autor:
Moshe Elkabets, J. Silvio Gutkind, Jennifer R. Grandis, Dexin Kong, Francis Burrows, Linda Kessler, Ari J. Rosenberg, Alan L. Ho, Sok Ching Cheong, Dinorah Friedmann-Morvinski, Gro Gausdal, Ofir Cohen, Irit Allon, Liza Vtorov, Monica Wainer, Ksenia M. Yegodayev, Jonathan Zorea, Avital Beeri Shnerb, Claire Saunders, Sooraj Mathukkada, Vijayasteltar Belsamma Liju, Talal Ben-Lulu, Mai Badarni, Manu Prasad, Sankar Jagadeeshan
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4703c78415f015112fa14bf1a713bfe5
https://doi.org/10.1158/0008-5472.22549778
https://doi.org/10.1158/0008-5472.22549778
Autor:
Moshe Elkabets, J. Silvio Gutkind, Jennifer R. Grandis, Dexin Kong, Francis Burrows, Linda Kessler, Ari J. Rosenberg, Alan L. Ho, Sok Ching Cheong, Dinorah Friedmann-Morvinski, Gro Gausdal, Ofir Cohen, Irit Allon, Liza Vtorov, Monica Wainer, Ksenia M. Yegodayev, Jonathan Zorea, Avital Beeri Shnerb, Claire Saunders, Sooraj Mathukkada, Vijayasteltar Belsamma Liju, Talal Ben-Lulu, Mai Badarni, Manu Prasad, Sankar Jagadeeshan
The survival rate for patients with head and neck cancer (HNC) diagnosed with cervical lymph node (cLN) or distant metastasis is low. Genomic alterations in the HRAS oncogene are associated with advanced tumor stage and metastasis in HNC. Elucidation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::693c79924a84b91e65852c828b02d803
https://doi.org/10.1158/0008-5472.c.6560198
https://doi.org/10.1158/0008-5472.c.6560198