Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Dino Volpin"'
Autor:
Alessandra D’Urso, Giorgio M. Bressan, Daniela Carnevale, Nicola Facchinello, Gaia Litteri, Giuseppe Lembo, Dario Bizzotto, Antonio Damato, Alfonso Colombatti, Francesco Da Ros, Patrizia Sabatelli, Paola Braghetta, Angelo Maffei, Alessandro Landolfi, Dino Volpin, Giuseppe Cifelli
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 32:2178-2184
Objective— Emilin-1 is a protein of elastic extracellular matrix involved in blood pressure (BP) control by negatively affecting transforming growth factor (TGF)-β processing. Emilin1 null mice are hypertensive. This study investigates how Emilin-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5f4ff148d2e8f2cc9af0aaec7ba3ee3
https://doi.org/10.1161/atvbaha.112.254664
https://doi.org/10.1161/atvbaha.112.254664
Autor:
Paolo Bonaldo, Dino Volpin, Natascia Tiso, Francesco Argenton, Martina Milanetto, Paola Braghetta
Publikováno v:
Developmental Dynamics. 237:222-232
Emilins are a family of extracellular matrix proteins with common structural organization and containing a characteristic N-terminal cysteine-rich domain. The prototype of this family, Emilin-1, is found in human and murine organs in association with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::627c5b91a32320b646f16fed2f3fafd7
https://doi.org/10.1002/dvdy.21402
https://doi.org/10.1002/dvdy.21402
Autor:
Giorgio M. Bressan, Alessandra Ferrari, Maddalena Adorno, Paola Braghetta, Claudio Colonnese, Gennaro Marino, Carmine Vecchione, Angelo Maffei, Giovanni Russo, Umberto Bettarini, Alessandra Aretini, Silvia Maretto, Giuseppe Lembo, Antonella Notte, Paolo Bonaldo, Sandra Soligo, Stefano Piccolo, Giulio Selvetella, Carla Fabbro, Dino Volpin, Giuseppe Cifelli, Sirio Dupont, Michelangelo Cordenonsi, Luca Zacchigna
Publikováno v:
Cell. 124:929-942
TGF-beta proteins are main regulators of blood vessel development and maintenance. Here, we report an unprecedented link between TGF-beta signaling and arterial hypertension based on the analysis of mice mutant for Emilin1, a cysteine-rich secreted g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::406dadb19a931a50cb42f78439a0cca0
https://doi.org/10.1016/j.cell.2005.12.035
https://doi.org/10.1016/j.cell.2005.12.035
Autor:
Paolo Bonaldo, Giorgio M. Bressan, Paola Braghetta, Dino Volpin, Paola de Gemmis, Carla Fabbro, Alfonso Colombatti
Publikováno v:
Journal of Biological Chemistry. 280:15749-15760
The location of regions that regulate transcription of the murine Emilin1 gene was investigated in a DNA fragment of 16.8 kb, including the entire gene and about 8.7 and 0.6 kb of 5'- and 3'-flanking sequences, respectively. The 8.7-kb segment contai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72d9605ce2a0da6cc66708aac1540244
https://doi.org/10.1074/jbc.m412548200
https://doi.org/10.1074/jbc.m412548200
Autor:
Alfonso Colombatti, Paola Braghetta, Roberto Doliana, Dino Volpin, Miriam Zanetti, Isabella Mura, Paolo Bonaldo, Patrizia Sabatelli, Giorgio M. Bressan
Publikováno v:
ResearcherID
Molecular and cellular biology
24:2 (2004): 638–650.
info:cnr-pdr/source/autori:M. ZANETTI, P. BRAGHETTA, P. SABATELLI, I. MURA, R. DOLIANA, A. COLOMBATTI, D. VOLPINJ, P. BONALDO, G.M. BRESSAN,/titolo:EMILIN-1 deficiency induces elastogenesis and vascular cell defects,/doi:/rivista:Molecular and cellular biology (Print)/anno:2004/pagina_da:638/pagina_a:650/intervallo_pagine:638–650/volume:24:2
Molecular and cellular biology
24:2 (2004): 638–650.
info:cnr-pdr/source/autori:M. ZANETTI, P. BRAGHETTA, P. SABATELLI, I. MURA, R. DOLIANA, A. COLOMBATTI, D. VOLPINJ, P. BONALDO, G.M. BRESSAN,/titolo:EMILIN-1 deficiency induces elastogenesis and vascular cell defects,/doi:/rivista:Molecular and cellular biology (Print)/anno:2004/pagina_da:638/pagina_a:650/intervallo_pagine:638–650/volume:24:2
EMILINs constitute a family of genes of the extracellular matrix with high structural similarity. Four genes have been identified so far in human and mouse. To gain insight into the function of this gene family, EMILIN-1 has been inactivated in the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70fa3e3236cd55bea2319c5a90bd9b4a
https://doi.org/10.1128/mcb.24.2.638-650.2004
https://doi.org/10.1128/mcb.24.2.638-650.2004
Autor:
Dino Volpin, Aram Megighian, Natascha Bergamin, Giorgio M. Bressan, William Irwin, Marta Columbaro, Luciano Merlini, Paolo Bonaldo, Carlo Reggiani, Paola Braghetta, Patrizia Sabatelli, Paolo Bernardi
Publikováno v:
Nature Genetics. 35:367-371
Collagen VI is an extracellular matrix protein that forms a microfilamentous network in skeletal muscles and other organs. Inherited mutations in genes encoding collagen VI in humans cause two muscle diseases, Bethlem myopathy and Ullrich congenital
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24e998e0f43a2b784b3c4aaea284a7a6
https://doi.org/10.1038/ng1270
https://doi.org/10.1038/ng1270
Publikováno v:
Mechanisms of Development. 102(1-2):145-156
A transgenic mouse line expressing the lacZ reporter under the control of a regulatory region of the col6a1 gene has been used to investigate differentiation of Schwann cells. The data suggest that: (1) activation of col6a1 gene transcription in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caf9ce9be873cba38d8f00cbe7ce8d08
Autor:
Dino Volpin, Giorgio M. Bressan, Carla Fabbro, Stefano Piccolo, Paola Braghetta, Davide Girotto
Publikováno v:
Journal of Biological Chemistry. 274:1759-1766
Analysis of the chromatin of different cell types has identified four DNase I-hypersensitive sites in the 5′-flanking region of the α1(VI) collagen gene, mapping at −4.6, −4.4, −2.5, and −0.1 kilobase (kb) from the RNA start site. The site
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2696c77ad5548830ceb60d3f8031d2d4
https://doi.org/10.1074/jbc.274.3.1759
https://doi.org/10.1074/jbc.274.3.1759
Autor:
Donatella Marvulli, Stefano Piccolo, Dino Volpin, Paolo Bonaldo, Paola Braghetta, Carla Fabbro, Giorgio M. Bressan
Publikováno v:
The Journal of Cell Biology
To identify regions involved in tissue specific regulation of transcription of the alpha1(VI) collagen chain, transgenic mice were generated carrying various portions of the gene's 5'-flanking sequence fused to the E. coli beta-galactosidase gene. An
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1506f0d04e3641018dad6b09a4bcca99
https://doi.org/10.1083/jcb.135.4.1163
https://doi.org/10.1083/jcb.135.4.1163
Publikováno v:
Developmental Dynamics. 206:447-454
The expression of type VI collagen has been studied in mouse tissues. By Northern blotting, the mRNA for the alpha 1 (VI) chain was detectable in whole embryos at 10.5 days postcoitum and steeply increased afterward. The messenger levels were high at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35734b5bd27be24f5418b9ba70da7e8f
https://doi.org/10.1002/(sici)1097-0177(199608)206:4<447::aid-aja10>3.0.co
https://doi.org/10.1002/(sici)1097-0177(199608)206:4<447::aid-aja10>3.0.co