Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Dino Severino"'
Publikováno v:
Tetrahedron Letters. 38:2311-2314
The copper/palladium-promoted heteroannulation of terminal acetylenic compounds in the presence of resin bound ortho-hydroxy aryl iodides is described. The process produces 2-substituted benzofuran derivatives in good yield and high purity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c47c3dcd409148b5e872bd643f9be28
https://doi.org/10.1016/s0040-4039(97)00301-8
https://doi.org/10.1016/s0040-4039(97)00301-8
Autor:
Patrizia Carpinelli, Paolo Cappella, Walter Croci, D. Berta, Aurelio Marsiglio, Paola Zugnoni, Paola Storici, Maurizio Rocchetti, Jan Klapwijk, Barbara Forte, Enrico Pesenti, Chiara Soncini, Ilaria Candiani, Paola Vianello, Fulvia Roletto, Simona Bindi, Alexander D. Cameron, Dino Severino, Maria Laura Giorgini, Roberta Artico, Jurgen Moll, Roberto Tonani, Daniele Fancelli, Mario Varasi, Rodrigo Bravo
Publikováno v:
Journal of medicinal chemistry. 49(24)
The optimization of a series of 5-phenylacetyl 1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole derivatives toward the inhibition of Aurora kinases led to the identification of compound 9d. This is a potent inhibitor of Aurora kinases that also shows low nan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd08cc812dadec488b873749bc6bc115
https://pubmed.ncbi.nlm.nih.gov/17125279
https://pubmed.ncbi.nlm.nih.gov/17125279
Autor:
Paolo Cappella, Daniele Fancelli, Cornel Catana, Patrizia Carpinelli, Alexander D. Cameron, Barbara Forte, and Anna Vulpetti, Aurelio Marsiglio, Simona Bindi, Maria Laura Giorgini, Valeria Pittalà, Chiara Soncini, Dino Severino, Paola Vianello, D. Berta, Fulvia Roletto, Patrizia Giordano, Sergio Mantegani, Paola Storici, Mario Varasi, Juergen Moll, Roberto Tonani, M. Meroni
Potent and selective Aurora kinase inhibitors were identified from the combinatorial expansion of the 1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole bi-cycle, a novel and versatile scaffold designed to target the ATP pocket of protein kinases. The most pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2969e30ed7075e89dcd470afde1746f4
http://hdl.handle.net/20.500.11769/54844
http://hdl.handle.net/20.500.11769/54844
Autor:
Pierpaolo Lovisolo, Dino Severino, Adelio Radice, Giancarlo Ghiselli, Augusto Chiari, Laura Giorgini, Daniele Fancelli
Publikováno v:
Pharmacological research. 32(4)
FCE 27677 ([(-)N-[2,6-bis(1-methylethyl)phenyl]-N'-[(4R,5R)-2- (4-dimethylaminophenyl)-4,5 dimethyl-dioxolan-2-yl]methylurea) is a new systemically available ACAT inhibitor belonging to the class of ketalic disubstituted ureas. When tested in microso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f852ed07f10592424a0b818c21d9550c
https://pubmed.ncbi.nlm.nih.gov/8866834
https://pubmed.ncbi.nlm.nih.gov/8866834
Autor:
Ettore Perrone, Giuliano Nannini, G. Meinardi, Dino Severino, Giovanni Biasoli, Angelo Bedeschi, Alberta Bianchi
Publikováno v:
The Journal of antibiotics. 34(4)
The synthesis and in vitro structure-activity relationships of 7-vinylenethioacetamido and thioacrylamido cephalosporins with various substituents at the 3-position are described. 7(Z)-beta-Vinylenethioacetamido cephalosporins proved the most active
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a55408d640dac9eecc21bbd130e8fd7
https://pubmed.ncbi.nlm.nih.gov/7275820
https://pubmed.ncbi.nlm.nih.gov/7275820
Autor:
Ettore Perrone, Dino Severino, Giuliano Nannini, Angelo Ceriani, Franco Giudici, G. Meinardi, Pier Nicola Girald
Publikováno v:
The Journal of antibiotics. 35(3)
The synthesis and in vitro activity of 7 alpha-methoxy-7 beta-vinylenethioacetamido cephalosporins with various substituents at the 3-position are described. These cephalosporins showed good activity against beta-lactamase producing Gram-negative bac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eed69b028af77ebdd7ac0a98abbf5e38
https://pubmed.ncbi.nlm.nih.gov/7076579
https://pubmed.ncbi.nlm.nih.gov/7076579
Autor:
L. Sala, G. Vita, G. Galli, Alberta Bianchi, P. Cozzi, Dino Severino, C. Confalonieri, Ferruccio Casabuona, G. Meinardi, Gisella Monti, I. De Carneri, Pier Nicola Giraldi, G. Molgora, Giuliano Nannini, Giovanni Biasoli
Publikováno v:
Chemischer Informationsdienst. 8
A series of 7-substituted alkyl-thio-acylaminocephalosporins with the following general formula were prepared and tested for in vitro antibacterial activity: (formula: see text). We tried in our research to find any relationship between antibacterial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::699b3deaa24d1df0d88fd6d5eb96c6d7
https://doi.org/10.1002/chin.197722364
https://doi.org/10.1002/chin.197722364
Autor:
Dino Severino, Angelo Ceriani, Pier Nicola Giraldi, Giuliano Nannini, Angelo Bedeschi, Ettore Perrone, Ivo De Carneri, G. Meinardi, Franco Buzzetti, Ferruccio Casabuona, Gisella Monti
Publikováno v:
The Journal of antibiotics. 34(11)
The synthesis and in vitro activity of 7-vinylenethioacetamido cephalosporins with a tetrazolo-pyridazine at the 3-position are described. These cephalosporins showed good activity against Gram-positive and Gram-negative bacteria. 7-[(Z)-beta-carboxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1fd33ec1dd01083ec94cdb79f06ce7c
https://pubmed.ncbi.nlm.nih.gov/7319908
https://pubmed.ncbi.nlm.nih.gov/7319908