Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Dinindu S, Senanayake"'
Autor:
Ahmad Taha, Nicole M. Stanton, Samuel C. Lee, Janice A. Royds, Rosemary M. A. Gordon, Ari Melnick, M. Leticia Castro, Tania L. Slatter, Marie-Sophie Fabre, Matthew R. Rowe, Dinindu S. Senanayake, Noelyn Hung, Melanie J. McConnell
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 4, p e0231470 (2020)
PLoS ONE, Vol 15, Iss 4, p e0231470 (2020)
The prognosis for people with the high-grade brain tumor glioblastoma is very poor, due largely to low cell death in response to genotoxic therapy. The transcription factor BCL6, a protein that normally suppresses the DNA damage response during immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee22bde415a113d7ecac8bc83f1267e6
Autor:
Andrew B. Munkacsi, Namal V. C. Coorey, Lisa M Connor, Bede P. Busby, Paul H. Atkinson, Jeffrey P. Sheridan, Dinindu S. Senanayake, Eliatan Niktab, Christina A. Roberts
Publikováno v:
npj Systems Biology and Applications, Vol 6, Iss 1, Pp 1-1 (2020)
NPJ Systems Biology and Applications
NPJ Systems Biology and Applications
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c8a2f516eeeae94082fba9a5514f50a
https://doi.org/10.1038/s41540-020-0129-9
https://doi.org/10.1038/s41540-020-0129-9
Autor:
Robert A. Maue, Stephen J. Bloor, Stephen L. Sturley, Dinindu S. Senanayake, Kirill Lagutin, Katsumi Higaki, Henry N. Ginsberg, Remy T. Schneider, Natalie Hammond, Andrew B. Munkacsi, Antonio Hernandez-Ono, Nicole Dahlson, Fannie W. Chen, Daniel S. Ory, Joyce J. Repa, Yiannis A. Ioannou
Publikováno v:
Journal of Biological Chemistry. 292:4395-4410
Niemann-Pick type C (NP-C) disease is a fatal genetic lipidosis for which there is no Food and Drug Administration (FDA)-approved therapy. Vorinostat, an FDA-approved inhibitor of histone deacetylases, ameliorates lysosomal lipid accumulation in cult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f9284e1ed04dfa5c1da8744c3e7f660
https://doi.org/10.1074/jbc.m116.770578
https://doi.org/10.1074/jbc.m116.770578
Autor:
Paul H. Atkinson, Lisa M Connor, Jeffrey P. Sheridan, Christina A. Roberts, Andrew B. Munkacsi, Eliatan Niktab, Dinindu S. Senanayake, Namal V. C. Coorey, Bede P. Busby
Publikováno v:
NPJ Systems Biology and Applications
npj Systems Biology and Applications, Vol 5, Iss 1, Pp 1-13 (2019)
npj Systems Biology and Applications, Vol 5, Iss 1, Pp 1-13 (2019)
Eukaryotic genetic interaction networks (GINs) are extensively described in the Saccharomyces cerevisiae S288C model using deletion libraries, yet being limited to this one genetic background, not informative to individual drug response. Here we crea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f52bd930e34324671872e7241b8d2009
http://europepmc.org/articles/PMC6776536
http://europepmc.org/articles/PMC6776536
Autor:
Andrew B, Munkacsi, Natalie, Hammond, Remy T, Schneider, Dinindu S, Senanayake, Katsumi, Higaki, Kirill, Lagutin, Stephen J, Bloor, Daniel S, Ory, Robert A, Maue, Fannie W, Chen, Antonio, Hernandez-Ono, Nicole, Dahlson, Joyce J, Repa, Henry N, Ginsberg, Yiannis A, Ioannou, Stephen L, Sturley
Publikováno v:
The Journal of biological chemistry. 292(11)
Niemann-Pick type C (NP-C) disease is a fatal genetic lipidosis for which there is no Food and Drug Administration (FDA)-approved therapy. Vorinostat, an FDA-approved inhibitor of histone deacetylases, ameliorates lysosomal lipid accumulation in cult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d3b903d993964132afab989954c6cb21
https://pubmed.ncbi.nlm.nih.gov/28031458
https://pubmed.ncbi.nlm.nih.gov/28031458
Autor:
Melanie J. McConnell, Nicole M. Jones, Katerina Hatzi, Marie-Sophie Fabre, Dinindu S. Senanayake, Ari Melnick
Publikováno v:
Cancer Research. 77:1523-1523
Glioblastoma (GBM) is the most common and most deadly brain tumor to occur in adults. Initially patients respond to radiation and chemotherapy, which primarily work by causing large amounts of DNA damage, causing apoptosis of the cells. However, this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f471b7ddeaa21dfba60e7dedd2ce0552
https://doi.org/10.1158/1538-7445.am2017-1523
https://doi.org/10.1158/1538-7445.am2017-1523