Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Dingkun Gui"'
Autor:
Xuling Li, Tingting Zhao, Junling Gu, Zhe Wang, Jing Lin, Rushang Wang, Tingting Duan, Zhenghai Li, Ruixue Dong, Weiming Wang, Kin-Fong Hong, Zhilong Liu, Wenbo Huang, Dingkun Gui, Hua Zhou, Youhua Xu
Publikováno v:
Chinese Medicine, Vol 17, Iss 1, Pp 1-19 (2022)
Abstract Background Brain impairment is one of a major complication of diabetes. Dietary flavonoids have been recommended to prevent brain damage. Astragalus membranaceus is a herbal medicine commonly used to relieve the complications of diabetes. Fl
Externí odkaz:
https://doaj.org/article/cd8e537a63f94ce6968acb1d31bcb62b
Autor:
Miaomiao Wei, Yuancheng Gao, Dongsheng Cheng, Haiying Zhang, Wei Zhang, Yilan Shen, Qunwei Huang, Xiaoning An, Bing Wang, Zhonghai Yu, Niansong Wang, Hongbo Chen, Youhua Xu, Dingkun Gui
Publikováno v:
Frontiers in Medicine, Vol 9 (2023)
IntroductionMitochondria dysfunction is one of the primary causes of tubular injury in acute kidney injury (AKI). Notoginsenoside Fc (Fc), a new saponin isolated from Panax notoginseng, exhibited numerous pharmacological actions. However, the benefic
Externí odkaz:
https://doaj.org/article/e21d6946f4884051a7e9b168d64993c1
Autor:
Qunwei Huang, Hongbo Chen, Kai Yin, Yilan Shen, Kanghong Lin, Xieyi Guo, Xiang Zhang, Niansong Wang, Wenfeng Xin, Youhua Xu, Dingkun Gui
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Mitochondrial abnormality is one of the main factors of tubular injury in diabetic nephropathy (DN). Formononetin (FMN), a novel isoflavonoid isolated from Astragalus membranaceus, has diverse pharmacological activities. However, the beneficial effec
Externí odkaz:
https://doaj.org/article/ecb118e55084483da5a64d5f720a4aa4
Autor:
Haiying Zhang, Kun Han, Dingkun Gui, Tingfang Chen, Ruifeng Yang, Lingling He, Xinbei Chang, Zhenzhen Jiang, Yan Wu, Yongping Guo
Publikováno v:
Journal of King Saud University: Science, Vol 32, Iss 2, Pp 1306-1311 (2020)
In order to explore the mechanism of Extract Gingko biloba (EGb761) inhibiting vascular calcification in rats with chronic kidney disease (CKD) through ROS-NF-κB signaling pathway, adult male healthy SD (Sprague Dawley) rats were selected as the res
Externí odkaz:
https://doaj.org/article/2092f7d841e445c1a664b030eb056b8e
Autor:
Jun Su, Chongting Gao, Ling Xie, Ying Fan, Yilan Shen, Qunwei Huang, Niansong Wang, Youhua Xu, Nizhi Yang, Dingkun Gui
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Astragaloside II (AS II), a novel saponin purified from Astragalus membranes, has been reported to modulate the immune response, repair tissue injury, and prevent inflammatory response. However, the protective effects of AS II on podocyte injury in d
Externí odkaz:
https://doaj.org/article/107bad3e532640e185b2be0ed10c230a
Autor:
Rui Xue, Ruonan Zhai, Ling Xie, Zening Zheng, Guihua Jian, Teng Chen, Jun Su, Chongting Gao, Niansong Wang, Xifei Yang, Youhua Xu, Dingkun Gui
Publikováno v:
Journal of Diabetes Research, Vol 2020 (2020)
Diabetic kidney disease (DKD) is a major cause of end-stage renal disease (ESRD), and therapeutic strategies for delaying its progression are limited. Loss of podocytes by apoptosis characterizes the early stages of DKD. To identify novel therapeutic
Externí odkaz:
https://doaj.org/article/6e73521580514a9b91813826fab255c0
Autor:
Ying Fan, Jing Zhang, Wenzhen Xiao, Kyung Lee, Zhengzhe Li, Jiejun Wen, Li He, Dingkun Gui, Rui Xue, Guihua Jian, Xiaohua Sheng, John Cijiang He, Niansong Wang
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract We previously reported a critical role of reticulon (RTN) 1A in mediating endoplasmic reticulum (ER) stress in kidney tubular cells and the expression of RTN1A correlates with the renal function and the severity of kidney injury in patients
Externí odkaz:
https://doaj.org/article/6552ee6c30a348679ffdcd2eba99d737
Autor:
Ruonan Zhai, Guihua Jian, Teng Chen, Ling Xie, Rui Xue, Chongting Gao, Niansong Wang, Youhua Xu, Dingkun Gui
Publikováno v:
Journal of Diabetes Research, Vol 2019 (2019)
This study was aimed at investigating the synergistical protective effects of Astragalus membranaceus (AG) and Panax notoginseng (NG) on podocyte injury in diabetic rats. Diabetes was induced in rats by a single intraperitoneal injection of streptozo
Externí odkaz:
https://doaj.org/article/78e214c6c77a46e0b388a95ee186e533
Publikováno v:
Cellular Physiology and Biochemistry, Vol 37, Iss 4, Pp 1491-1502 (2015)
Background/Aims: Hyperuricemia is an independent risk factor for chronic kidney disease and cardiovascular disease. Here, we examined the combined protective effects of Chinese herbal formula Si-Wu-Tang and Er-Miao-San on hyperuricemia and renal impa
Externí odkaz:
https://doaj.org/article/86ad19cb98b74e57ab3367caed8cf974
Publikováno v:
Cellular Physiology and Biochemistry, Vol 35, Iss 4, Pp 1425-1436 (2015)
Background: Epithelial-to-mesenchymal transition (EMT) is a potential pathway leading to podocyte depletion and proteinuria in diabetic kidney disease (DKD). Here, we investigated the protective effects of Emodin (EMO) on high glucose (HG) induced-po
Externí odkaz:
https://doaj.org/article/52916fafdc714874baf05e8b50a651c9