Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Dingeman C Rijken"'
Autor:
Shiraazkhan Abdul, Miet Peeters, Els Brouwers, Joyce J M C Malfliet, Frank W G Leebeek, Paul J Declerck, Dingeman C Rijken, Shirley Uitte de Willige
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0196911 (2018)
Around 70% of circulating alpha-2-antiplasmin (α2AP), the main natural plasmin inhibitor, is N-terminally cleaved between residues Pro12 and Asn13 by antiplasmin-cleaving enzyme. This converts native Met-α2AP into the more potent fibrinolysis inhib
Externí odkaz:
https://doaj.org/article/e2a6b9d1253348ceb014e9f164bf1048
Autor:
Shirley Uitte de Willige, Fiona M Keane, David G Bowen, Joyce J M C Malfliet, H Emma Zhang, Bharvi Maneck, Geoffrey W McCaughan, Frank W G Leebeek, Dingeman C Rijken, Mark D Gorrell
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178987 (2017)
BACKGROUND AND AIM:Circulating fibroblast activation protein (cFAP) is a constitutively active enzyme expressed by activated fibroblasts that has both dipeptidyl peptidase and endopeptidase activities. We aimed to assess the correlation between cFAP
Externí odkaz:
https://doaj.org/article/f1745d1ee4c94a02bdd005d616eb8aec
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171271 (2017)
Due to controversial evidence in the literature pertaining to the activity of plasminogen activator inhibitor-1 in platelets, we examined the effects of residual platelets present in plasma (a potential pre-analytical variable) on various plasminogen
Externí odkaz:
https://doaj.org/article/0e119a2a93e840088267178c69b4d9aa
Autor:
Zelda de Lange, Dingeman C Rijken, Tiny Hoekstra, Karin R Conradie, Johann C Jerling, Marlien Pieters
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83151 (2013)
Data on genetic and environmental factors influencing PAI-1 levels and their consequent effect on clot lysis in black African populations are limited. We identified polymorphisms in the promoter area of the PAI-1 gene and determined their influence o
Externí odkaz:
https://doaj.org/article/60698d38e5fc425fb1cc22d24879b8e2
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48881 (2012)
Studies in populations of European descent show longer plasma clot lysis times (CLT) in patients with cardiovascular disease (CVD) than in controls. No data are available on the association between CVD risk factors and fibrinolytic potential in black
Externí odkaz:
https://doaj.org/article/9486cb8daae548ebba81fef8410a11f7
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e41966 (2012)
Several proteins are known to bind to a fibrin network and to change clot properties or function. In this study we aimed to get an overview of fibrin clot-bound plasma proteins. A plasma clot was formed by adding thrombin, CaCl(2) and aprotinin to ci
Externí odkaz:
https://doaj.org/article/7ad438bf278e4f2db10707a0d7e5aa1b
Autor:
Judith J. de Vries, Chantal Visser, Maureen van Ommen, Casper Rokx, Els van Nood, Eric C.M. van Gorp, Marco Goeijenbier, Johannes P.C. van den Akker, Henrik Endeman, Dingeman C. Rijken, Marieke J.H.A. Kruip, Miranda Weggeman, Jaap Koopman, Moniek de Maat
Publikováno v:
TH Open.
Background: Fibrinogen variants as a result of alternative mRNA splicing or protein degradation can affect fibrin(ogen) functions. The levels of these variants might be altered during COVID-19, potentially affecting disease severity or the thrombosis
Autor:
Judith J. de Vries, Chantal Visser, Lotte Geers, Johan A. Slotman, Nadine D. van Kleef, Coen Maas, Hannelore I. Bax, Jelle R. Miedema, Eric C.M. van Gorp, Marco Goeijenbier, Johannes P.C. van den Akker, Henrik Endeman, Dingeman C. Rijken, Marieke J.H.A. Kruip, Moniek P.M. de Maat
Publikováno v:
Journal of Thrombosis and Haemostosis, 20(6), 1412-1420. Wiley-Blackwell Publishing Ltd
BACKGROUND: Severe acute respiratory syndrome coronavirus 2 infection is associated with an increased incidence of thrombosis.OBJECTIVES: By studying the fibrin network structure of coronavirus disease 2019 (COVID-19) patients, we aimed to unravel pa
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology, 40, 554-569. Lippincott Williams & Wilkins
Arteriosclerosis, Thrombosis, and Vascular Biology
Arteriosclerosis, Thrombosis, and Vascular Biology
Supplemental Digital Content is available in the text.
Objective: Post-translational modifications of fibrinogen influence the occurrence and progression of thrombotic diseases. In this systematic review, we assessed the current literature on po
Objective: Post-translational modifications of fibrinogen influence the occurrence and progression of thrombotic diseases. In this systematic review, we assessed the current literature on po
Autor:
Dingeman C. Rijken, Marjon H. Cnossen, Moniek P.M. de Maat, Marieke J. H. A. Kruip, Elise J Huisman, Frank W G Leebeek, Caroline S B Veen, Regina Kom-Gortat
Publikováno v:
Haemophilia, 26(3), E106-E115. Wiley-Blackwell Publishing Ltd
Introduction: Diagnostic evaluation of patients with a bleeding tendency remains challenging, as no disorder is identified in approximately 50% of patients. An impaired interplay of several haemostatic factors might explain bleeding phenotype in thes