Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Dingcheng Gao"'
Autor:
Yi Ban, Yue Zou, Yingzhuo Liu, Sharrel Lee, Robert B Bednarczyk, Jianting Sheng, Yuliang Cao, Stephen TC Wong, Dingcheng Gao
Publikováno v:
eLife, Vol 12 (2024)
Epithelial-to-mesenchymal transition (EMT) contributes significantly to chemotherapy resistance and remains a critical challenge in treating advanced breast cancer. The complexity of EMT, involving redundant pro-EMT signaling pathways and its paradox
Externí odkaz:
https://doaj.org/article/fabd83d377c64a498aba96c2a8d493c9
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-21 (2024)
Abstract Physiological signal monitoring and driver behavior analysis have gained increasing attention in both fundamental research and applied research. This study involved the analysis of driving behavior using multimodal physiological data collect
Externí odkaz:
https://doaj.org/article/f0dba19f086247449aaadc89e927ff75
Autor:
Michael J. P. Crowley, Bhavneet Bhinder, Geoffrey J. Markowitz, Mitchell Martin, Akanksha Verma, Tito A. Sandoval, Chang-Suk Chae, Shira Yomtoubian, Yang Hu, Sahil Chopra, Diamile A. Tavarez, Paolo Giovanelli, Dingcheng Gao, Timothy E. McGraw, Nasser K. Altorki, Olivier Elemento, Juan R. Cubillos-Ruiz, Vivek Mittal
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
The IRE1α-XBP1 arm of the unfolded protein response (UPR) has been associated with immunosuppression and cancer progression. Here the authors show that IRE1α-XBP1 activation is associated with poor overall survival in patients with non-small cell l
Externí odkaz:
https://doaj.org/article/77b087499a044dd7be6eee31431dbce9
Autor:
Divya Ramchandani, Mirela Berisa, Diamile A. Tavarez, Zhuoning Li, Matthew Miele, Yang Bai, Sharrell B. Lee, Yi Ban, Noah Dephoure, Ronald C. Hendrickson, Suzanne M. Cloonan, Dingcheng Gao, Justin R. Cross, Linda T. Vahdat, Vivek Mittal
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Copper depletion has been reported to improve survival in patients with triple negative breast cancer (TNBC) but the underlying mechanisms are not completely understood. Here, the authors show that copper chelation reduces mitochondrial oxidative pho
Externí odkaz:
https://doaj.org/article/84f3fe60af3143d88e9dc7a8c45b3a7d
Autor:
Shira Yomtoubian, Sharrell B. Lee, Akanksha Verma, Franco Izzo, Geoffrey Markowitz, Hyejin Choi, Leandro Cerchietti, Linda Vahdat, Kristy A. Brown, Eleni Andreopoulou, Olivier Elemento, Jenny Chang, Giorgio Inghirami, Dingcheng Gao, Seongho Ryu, Vivek Mittal
Publikováno v:
Cell Reports, Vol 30, Iss 3, Pp 755-770.e6 (2020)
Summary: Epigenetic changes are increasingly being appreciated as key events in breast cancer progression. However, breast cancer subtype-specific epigenetic regulation remains poorly investigated. Here we report that EZH2 is a leading candidate of e
Externí odkaz:
https://doaj.org/article/dc5eae5543644a968ae0a2033cf31557
Autor:
Marcin Stawowczyk, Max D. Wellenstein, Sharrell B. Lee, Shira Yomtoubian, Anna Durrans, Hyejin Choi, Navneet Narula, Nasser K. Altorki, Dingcheng Gao, Vivek Mittal
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 2, Pp 55-64 (2017)
Molecularly targeted therapies benefit approximately 15–20% of non-small cell lung cancer (NSCLC) patients carrying specific drug-sensitive mutations. Thus, there is a clinically unmet need for the identification of novel targets for drug developme
Externí odkaz:
https://doaj.org/article/97075bf7c3e04161aaec3dbf287501d4
Autor:
Hyejin Choi, Jianting Sheng, Dingcheng Gao, Fuhai Li, Anna Durrans, Seongho Ryu, Sharrell B. Lee, Navneet Narula, Shahin Rafii, Olivier Elemento, Nasser K. Altorki, Stephen T.C. Wong, Vivek Mittal
Publikováno v:
Cell Reports, Vol 10, Iss 7, Pp 1187-1201 (2015)
Emerging studies have begun to demonstrate that reprogrammed stromal cells play pivotal roles in tumor growth, metastasis, and resistance to therapy. However, the contribution of stromal cells to non-small-cell lung cancer (NSCLC) has remained undere
Externí odkaz:
https://doaj.org/article/b8dcb02418354e378974693d3b80fe53
Autor:
Anna Durrans, Dingcheng Gao, Ravi Gupta, Kari R Fischer, Hyejin Choi, Tina El Rayes, Seongho Ryu, Abu Nasar, Cathy F Spinelli, Weston Andrews, Olivier Elemento, Daniel Nolan, Brendon Stiles, Shahin Rafii, Navneet Narula, Ramana Davuluri, Nasser K Altorki, Vivek Mittal
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129123 (2015)
Lung cancer is the leading cause of cancer related mortality worldwide, with non-small cell lung cancer (NSCLC) as the most prevalent form. Despite advances in treatment options including minimally invasive surgery, CT-guided radiation, novel chemoth
Externí odkaz:
https://doaj.org/article/2ee6bf417a6b4758a056f33c3cf94660
Autor:
Seongho Ryu, Natasha Joshi, Kevin McDonnell, Jongchan Woo, Hyejin Choi, Dingcheng Gao, William R McCombie, Vivek Mittal
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16403 (2011)
MicroRNAs (miRNAs) are key regulators of gene expression and contribute to a variety of biological processes. Abnormal miRNA expression has been reported in various diseases including pathophysiology of breast cancer, where they regulate protumorigen
Externí odkaz:
https://doaj.org/article/5fe61d480dda4632bd5189fd0255c22d
Autor:
Vivek Mittal, Randolph S. Watnick, Lars A. Akslen, Ole J. Halvorsen, Karsten Gravdal, Svein A. Haukaas, Sharrell B. Lee, Diane Bielenberg, Natasha Joshi, Seongho Ryu, Dingcheng Gao, Hyejin Choi, Suming Wang, Tina El Rayes, Nandita Bhattacharya, Raúl Catena
Supplementary Figure S12 - PDF file 118K, Prosaposin mimetic peptide DWLPK upregulates Tsp-1 in tumor-recruited Gr1 cells in the lung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d22bd50f76af85a478af3bd31ea3413c
https://doi.org/10.1158/2159-8290.22528814.v1
https://doi.org/10.1158/2159-8290.22528814.v1