Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ding-Yuan Tian"'
Autor:
Ding-Yuan Tian, Jun Wang, Bin-Lu Sun, Zhen Wang, Wei Xu, Yang Chen, Ying-Ying Shen, Hui-Yun Li, Dong-Wan Chen, Fa-Ying Zhou, Xu Yi, Gui-Hua Zeng, Zhi-Qiang Xu, Li-Yong Chen, Jin-Tai Yu, Yan-Jiang Wang, Yan-Jie Yin, Xiu-Yuan Hao
Publikováno v:
Chinese Medical Journal, Vol 134, Iss 2, Pp 173-177 (2021)
Abstract. Background:. Recent studies suggest that a healthy diet helps to prevent the development of Alzheimer disease (AD). This study aimed to investigate whether spicy food consumption is associated with cognition and cerebrospinal fluid (CSF) bi
Externí odkaz:
https://doaj.org/article/2afd3c6daa3e49ac8cc952c222ef5673
Autor:
Si-Han Chen, Ding-Yuan Tian, Ying-Ying Shen, Yuan Cheng, Dong-Yu Fan, Hao-Lun Sun, Chen-Yang He, Pu-Yang Sun, Xian-Le Bu, Fan Zeng, Juan Liu, Juan Deng, Zhi-Qiang Xu, Yang Chen, Yan-Jiang Wang
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-11 (2020)
Abstract Deficits in the clearance of amyloid β-protein (Aβ) play a pivotal role in the pathogenesis of sporadic Alzheimer’s disease (AD). The roles of blood monocytes in the development of AD remain unclear. In this study, we sought to investiga
Externí odkaz:
https://doaj.org/article/020f408f79fa46908782cba0b3ef9b3e
Publikováno v:
Translational Neurodegeneration, Vol 9, Iss 1, Pp 1-11 (2020)
Abstract Alzheimer’s disease (AD) is the most common type of dementia, and no disease-modifying treatments are available to halt or slow its progression. Amyloid-beta (Aβ) is suggested to play a pivotal role in the pathogenesis of AD, and clearanc
Externí odkaz:
https://doaj.org/article/a8ecfd0780224263b1fd6acb2067c3ea
Autor:
Bin-Lu Sun, Wei-Wei Li, Jun Wang, Ya-Li Xu, Hao-Lun Sun, Ding-Yuan Tian, Yan-Jiang Wang, Xiu-Qing Yao
Emerging evidence suggests that gut microbiota dysbiosis plays a role in neurodegenerative disorders. However, whether the composition and diversity of the gut microbiota are altered in tauopathies remains largely unknown. This study was aimed to exa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8633be908b7e71dc3456f707053a9c9c
https://doi.org/10.3233/aiad220017
https://doi.org/10.3233/aiad220017
Autor:
Ding-Yuan Tian, Hongwen Zhao, Xian-Le Bu, Chen-Yang He, Mao-Zhi Tang, Dong-Yu Fan, Hao-Lun Sun, Yan-Jiang Wang, Ying-Ying Shen, Pu-Yang Sun, Gui-Hua Zeng, Cheng-Rong Tan, Xue-Lian Hu, Jun Wang, Yuan Cheng, Zhong-Yuan Yu, Ye-Ran Wang, Si-Han Chen, Qian-Guang Pan, Zhen-Qian Zhuang
Publikováno v:
Molecular Psychiatry. 26:6074-6082
Amyloid-β (Aβ) accumulation in the brain is a pivotal event in the pathogenesis of Alzheimer's disease (AD), and its clearance from the brain is impaired in sporadic AD. Previous studies suggest that approximately half of the Aβ produced in the br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad7e3816ff6f9d2c98511ae0a75955ca
https://doi.org/10.1038/s41380-021-01073-6
https://doi.org/10.1038/s41380-021-01073-6
Autor:
Ding-Yuan Tian, Xian-Le Bu, Pu-Yang Sun, Zhi-Qiang Xu, Yang Chen, Chen-Yang He, Yan-Jiang Wang, Hao-Lun Sun, Dong-Yu Fan, Ying-Ying Shen, Si-Han Chen, Fan Zeng, Juan Liu, Yuan Cheng, Juan Deng
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-11 (2020)
Translational Psychiatry
Translational Psychiatry
Deficits in the clearance of amyloid β-protein (Aβ) play a pivotal role in the pathogenesis of sporadic Alzheimer’s disease (AD). The roles of blood monocytes in the development of AD remain unclear. In this study, we sought to investigate the al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8bd5e7e7249e7ee8ac4bcd2c2a5c8d7
https://doaj.org/article/020f408f79fa46908782cba0b3ef9b3e
https://doaj.org/article/020f408f79fa46908782cba0b3ef9b3e
Autor:
Chen-Yang He, Ding-Yuan Tian, Si-Han Chen, Wang-Sheng Jin, Yuan Cheng, Jia-Yan Xin, Wei-Wei Li, Gui-Hua Zeng, Cheng-Rong Tan, Jie-Ming Jian, Dong-Yu Fan, Jun-Rong Ren, Yu-Hui Liu, Yan-Jiang Wang, Fan Zeng
Publikováno v:
Neuroscience bulletin.
The extracellular domain (p75ECD) of p75 neurotrophin receptor (p75NTR) antagonizes Aβ neurotoxicity and promotes Aβ clearance in Alzheimer's disease (AD). The impaired shedding of p75ECD is a key pathological process in AD, but its regulatory mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0ea8cb5aaa796b0eefdaf567c56f73c
https://pubmed.ncbi.nlm.nih.gov/35974288
https://pubmed.ncbi.nlm.nih.gov/35974288
Autor:
Hao-Lun Sun, Jun-Ping Wang, Si-Han Chen, Jun Wang, Yuan Cheng, Pu-Yang Sun, Weihong Song, Zhian Hu, Dong-Yu Fan, Chen-Yang He, Xiaowei Chen, Ding-Yuan Tian, Xian-Le Bu, Yan-Jiang Wang, Hua-Dong Zhou, Zhong-Yuan Yu, Cheng-Rong Tan, Yang Chen
Publikováno v:
Molecular Psychiatry. 26:5568-5577
It is traditionally believed that cerebral amyloid-beta (Aβ) deposits are derived from the brain itself in Alzheimer's disease (AD). Peripheral cells such as blood cells also produce Aβ. The role of peripherally produced Aβ in the pathogenesis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bf3773fb3dc24e6285393c86755e52d
https://doi.org/10.1038/s41380-020-0842-1
https://doi.org/10.1038/s41380-020-0842-1
Autor:
Wei-Wei Li, Jin-Tai Yu, Li-Yong Chen, Wei Xu, Wang-Sheng Jin, Chi Zhu, Yang Xiang, Xiaowei Chen, Zhiming Zhu, Zhian Hu, Xian-Le Bu, Hua-Dong Zhou, Jun Wang, Zhen Wang, Ding-Yuan Tian, Gui-Hua Zeng, Bin-Lu Sun, Yan-Jiang Wang, Yu-Hui Liu, Lin-Lin Shen, Weihong Song
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-12 (2020)
Translational Psychiatry
Translational Psychiatry
Alzheimer’s disease (AD) is the most common cause of age-related dementia and is currently incurable. The failures of current clinical trials and the establishment of modifiable risk factors have shifted the AD intervention from treatment to preven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12e03b482cf0280e33986604436906e3
http://link.springer.com/article/10.1038/s41398-020-00918-y
http://link.springer.com/article/10.1038/s41398-020-00918-y
Autor:
Si-Han Chen, Man-Yu Xu, Ying-Ying Shen, Yuan Cheng, Yan-Jiang Wang, Xian-Le Bu, Chen-Yang He, Dong-Yu Fan, Cheng-Rong Tan, Gui-Hua Zeng, Ding-Yuan Tian, An-Yu Shi
Publikováno v:
Neurosci Bull
Deficits in the clearance of amyloid β protein (Aβ) by the peripheral system play a critical role in the pathogenesis of sporadic Alzheimer’s disease (AD). Impaired uptake of Aβ by dysfunctional monocytes is deemed to be one of the major mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7edaab7a0c68ad2f18b5d0199f3b265
https://europepmc.org/articles/PMC8975919/
https://europepmc.org/articles/PMC8975919/