Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Ding-Sheng Jiang"'
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-18 (2024)
Abstract During oxidative phosphorylation, mitochondria continuously produce reactive oxygen species (ROS), and untimely ROS clearance can subject mitochondria to oxidative stress, ultimately resulting in mitochondrial damage. Mitophagy is essential
Externí odkaz:
https://doaj.org/article/5ee8950772fb4284ac8c933f06223a50
Autor:
Xiaoxuan Zhong, Xiang Wei, Yan Xu, Xuehai Zhu, Bo Huo, Xian Guo, Gaoke Feng, Zihao Zhang, Xin Feng, Zemin Fang, Yuxuan Luo, Xin Yi, Ding-Sheng Jiang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 2, Pp 712-728 (2024)
Coronary restenosis is an important cause of poor long-term prognosis in patients with coronary heart disease. Here, we show that lysine methyltransferase SMYD2 expression in the nucleus is significantly elevated in serum- and PDGF-BB-induced vascula
Externí odkaz:
https://doaj.org/article/f743ea76053e4e0998d71f1fc7cec4a8
Publikováno v:
Epigenetics & Chromatin, Vol 16, Iss 1, Pp 1-14 (2023)
Abstract Histone methyltransferase SETDB1 (SET domain bifurcated histone lysine methyltransferase 1, also known as ESET or KMT1E) is known to be involved in the deposition of the di- and tri-methyl marks on H3K9 (H3K9me2 and H3K9me3), which are assoc
Externí odkaz:
https://doaj.org/article/6626538542614c6b9204535d4eadc4fb
Publikováno v:
Cell Division, Vol 18, Iss 1, Pp 1-11 (2023)
Abstract Background Aberrant proliferation of vascular smooth muscle cells (VSMCs) is the cause of neointima formation followed by vascular injury. Autophagy is involved in this pathological process, but its function is controversial. Recently, we fo
Externí odkaz:
https://doaj.org/article/eaeebdd9bec947deb5730a11d4fc69a3
Autor:
Juan Shi, Qun-Hui Wang, Xiang Wei, Bo Huo, Jian-Nan Ye, Xin Yi, Xin Feng, Ze-Min Fang, Ding-Sheng Jiang, Ming-Jia Ma
Publikováno v:
Molecular Medicine, Vol 29, Iss 1, Pp 1-15 (2023)
Abstract Background E1A-associated 300-kDa protein (P300), an endogenous histone acetyltransferase, contributes to modifications of the chromatin landscape of genes involved in multiple cardiovascular diseases. Ferroptosis of vascular smooth muscle c
Externí odkaz:
https://doaj.org/article/f43c333827e04c07ae0c8178cade4d01
Publikováno v:
Cell Death and Disease, Vol 14, Iss 3, Pp 1-13 (2023)
Abstract Ferroptosis is an iron-dependent regulated cell death driven by excessive lipid peroxidation. Inflammation is one common and effective physiological event that protects against various stimuli to maintain tissue homeostasis. However, the dys
Externí odkaz:
https://doaj.org/article/7f0615b209994392ae498407e6782701
Publikováno v:
MedComm, Vol 4, Iss 3, Pp n/a-n/a (2023)
Abstract Ferroptosis is a form of regulated cell death triggered by the iron‐dependent peroxidation of phospholipids. Interactions of iron and lipid metabolism factors jointly promote ferroptosis. Ferroptosis has been demonstrated to be involved in
Externí odkaz:
https://doaj.org/article/1b4f9d1f4468434db3f9482040eb41c3
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 153, Iss , Pp 113547- (2022)
Autophagy is a well-conserved biological process that maintains homeostasis. Accumulating evidence has revealed that autophagy plays an important role in various cardiovascular diseases, such as aneurysm, aortic dissection, atherosclerosis, and myoca
Externí odkaz:
https://doaj.org/article/898340995866438db81034226ecee6ac
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Thoracic aortic aneurysm (TAA) is a life-threatening cardiovascular disease whose formation is reported to be associated with massive vascular inflammatory responses. To elucidate the roles of immune cell infiltration in the pathogenesis underlying T
Externí odkaz:
https://doaj.org/article/e375bbb73803451e93903800850fc38f
Autor:
Yue Chen, Xin Yi, Bo Huo, Yi He, Xian Guo, Zihao Zhang, Xiaoxuan Zhong, Xin Feng, Ze-Min Fang, Xue-Hai Zhu, Xiang Wei, Ding-Sheng Jiang
Publikováno v:
Pharmacological Research, Vol 177, Iss , Pp 106122- (2022)
Smooth muscle cell (SMC) loss is the characteristic feature in the pathogenesis of aortic dissection (AD), and ferroptosis is a novel iron-dependent regulated cell death driven by the excessive lipid peroxidation accumulation. However, whether target
Externí odkaz:
https://doaj.org/article/65725168f6e84ff7b7a66408fd67ca44