Výsledky vyhledávání - "Ding-Hui Wan"

Akademický článek

Litopenaeus vannamei sterile-alpha and armadillo motif containing protein (LvSARM) is involved in regulation of Penaeidins and antilipopolysaccharide factors.

Autor: Pei-Hui Wang, Zhi-Hua Gu, Ding-Hui Wan, Wei-Bin Zhu, Wei Qiu, Shao-Ping Weng, Xiao-Qiang Yu, Jian-Guo He

Publikováno v: PLoS ONE, Vol 8, Iss 2, p e52088 (2013)

The Toll-like receptor (TLR)-mediated NF-κB pathway is tightly controlled because overactivation may result in severe damage to the host, such as in the case of chronic inflammatory diseases and cancer. In mammals, sterile-alpha and armadillo motif-

Externí odkaz: https://doaj.org/article/6d2a6a4f073e40078da49569bef35acd

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Akademický článek

Analysis of expression, cellular localization, and function of three inhibitors of apoptosis (IAPs) from Litopenaeus vannamei during WSSV infection and in regulation of antimicrobial peptide genes (AMPs).

Autor: Pei-Hui Wang, Ding-Hui Wan, Zhi-Hua Gu, Wei Qiu, Yong-Gui Chen, Shao-Ping Weng, Xiao-Qiang Yu, Jian-Guo He

Publikováno v: PLoS ONE, Vol 8, Iss 8, p e72592 (2013)

Inhibitors of apoptosis (IAPs) play important roles in apoptosis and NF-κB activation. In this study, we cloned and characterized three IAPs (LvIAP1-3) from the Pacific white shrimp, Litopenaeusvannamei. LvIAP1-3 proteins shared signature domains an

Externí odkaz: https://doaj.org/article/4b12f6fe6a4843eeae73812e97138666

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Akademický článek

Characterization of four novel caspases from Litopenaeus vannamei (Lvcaspase2-5) and their role in WSSV infection through dsRNA-mediated gene silencing.

Autor: Pei-Hui Wang, Ding-Hui Wan, Yong-Gui Chen, Shao-Ping Weng, Xiao-Qiang Yu, Jian-Guo He

Publikováno v: PLoS ONE, Vol 8, Iss 12, p e80418 (2013)

Apoptosis plays an important role in white spot syndrome virus (WSSV) pathogenesis, and caspases are central players in apoptosis. Here, we cloned four novel caspases (Lvcaspase2-5) from the Pacific white shrimp Litopenaeus vannamei, and investigated

Externí odkaz: https://doaj.org/article/e95e35c648594ccda2f415a527fb82ea

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Akademický článek

The shrimp NF-κB pathway is activated by white spot syndrome virus (WSSV) 449 to facilitate the expression of WSSV069 (ie1), WSSV303 and WSSV371.

Autor: Pei-Hui Wang, Zhi-Hua Gu, Ding-Hui Wan, Ming-Yan Zhang, Shao-Ping Weng, Xiao-Qiang Yu, Jian-Guo He

Publikováno v: PLoS ONE, Vol 6, Iss 9, p e24773 (2011)

The Toll-like receptor (TLR)-mediated NF-κB pathway is essential for defending against viruses in insects and mammals. Viruses also develop strategies to utilize this pathway to benefit their infection and replication in mammal hosts. In invertebrat

Externí odkaz: https://doaj.org/article/8635307dab3546348cb55c0ca377528d

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The shrimp IKK–NF-κB signaling pathway regulates antimicrobial peptide expression and may be subverted by white spot syndrome virus to facilitate viral gene expression

Autor: Shaoping Weng, Bodu Liu, Pei-Hui Wang, Xiao-Qiang Yu, Ding-Hui Wan, Zhi-Hua Gu, Jianguo He, Xian-De Huang

Publikováno v: Cellular and Molecular Immunology

The IκB kinases IKKα and IKKβ and the IKK-related kinases TANK-binding kinase 1 (TBK1) and IKKε are the master regulators of the NF-κB signaling pathway. Although this pathway has been extensively studied in mammals, less attention has been paid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db2fb55a6f6f9da6cb7f6bc63f766a9
https://doi.org/10.1038/cmi.2013.30

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Molecular cloning, characterization and expression analysis of two novel Tolls (LvToll2 and LvToll3) and three putative Spätzle-like Toll ligands (LvSpz1–3) from Litopenaeus vannamei

Autor: Pei-Hui Wang, Jian-ping Liang, Xiao-Qiang Yu, Zhi-Hua Gu, Jianguo He, Shaoping Weng, Ding-Hui Wan

Publikováno v: Developmental & Comparative Immunology. 36:359-371

Toll-like receptor-mediated NF-κB pathways are essential for inducing immune related-gene expression in the defense against bacterial, fungal and viral infections in insects and mammals. Although a Toll receptor (LvToll1) was cloned in Litopenaeus v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b819a50ee5329dabb16b357d22603024
https://doi.org/10.1016/j.dci.2011.07.007

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Litopenaeus vannamei tumor necrosis factor receptor-associated factor 6 (TRAF6) responds to Vibrio alginolyticus and white spot syndrome virus (WSSV) infection and activates antimicrobial peptide genes

Autor: Jianguo He, Pei-Hui Wang, Ding-Hui Wan, Shaoping Weng, Zhi-Hua Gu, Xiao-Qiang Yu, Xiexiong Deng

Publikováno v: Developmental & Comparative Immunology. 35:105-114

Tumor necrosis factor receptor (TNFR)-associated factor 6 (TRAF6) is a key signaling adaptor protein not only for the TNFR superfamily but also for the Interleukin-1 receptor/Toll-like receptor (IL-1/TLR) superfamily. To investigate TRAF6 function in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b68667eea1a10641fb616f9cc0eab95
https://doi.org/10.1016/j.dci.2010.08.013

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Litopenaeus vannamei Toll-interacting protein (LvTollip) is a potential negative regulator of the shrimp Toll pathway involved in the regulation of the shrimp antimicrobial peptide gene penaeidin-4 (PEN4)

Autor: Ding-Hui Wan, Shaoping Weng, Xiao-Qiang Yu, Wei Qiu, Jianguo He, Zhi-Hua Gu, Wei-Bin Zhu, Pei-Hui Wang, Yonggui Chen

Publikováno v: Developmental and comparative immunology. 40(3-4)

The Toll-like receptor (TLR)-nuclear factor (NF)-κB signaling pathway is evolutionarily conserved from insects to mammals as a regulator of the expression of immune-related genes. In mammals, TLR-NF-κB signaling is tightly controlled because excess

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d037d5f8aa9583966573ccdbd59f9670
https://pubmed.ncbi.nlm.nih.gov/23500511

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