Zobrazeno 1 - 10
of 296
pro vyhledávání: '"Ding Qu"'
Autor:
Xietao Ye, Yuping Liu, Liangyin Wei, Yeyang Sun, Xiaoran Zhang, Hong Wang, Hong Guo, Xiaoying Qin, Xiaoqi Li, Ding Qu, Jiege Huo, Yan Chen
Publikováno v:
Advanced Science, Vol 11, Iss 38, Pp n/a-n/a (2024)
Abstract Microsatellite‐stable colorectal cancer (MSS‐CRC) exhibits resistance to programmed cell death protein‐1 (PD‐1) therapy. Improving the infiltration and tumor recognition of cytotoxic T‐lymphocytes (CTLs) is a promising strategy, bu
Externí odkaz:
https://doaj.org/article/b263e04093ac4542967b1ea06821e832
Autor:
Hong Guo, Xia Li, Dengxuan Mao, Hong Wang, Liangyin Wei, Ding Qu, Xiaoying Qin, Xiaoqi Li, Yuping Liu, Yan Chen
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract The insufficient abundance and weak activity of tumour-infiltrating lymphocytes (TILs) are two important reasons for the poor efficacy of PD-1 inhibitors in hepatocellular carcinoma (HCC) treatment. The combined administration of tanshinone
Externí odkaz:
https://doaj.org/article/20208845e30440a29984cf1059067259
Autor:
Jiachen Shi, Qiuling Ma, Wenting Su, Congyan Liu, Huangqin Zhang, Yuping Liu, Xiaoqi Li, Xi Jiang, Chang Ge, Fei Kong, Yan Chen, Ding Qu
Publikováno v:
Biomaterials Research, Vol 27, Iss 1, Pp 1-15 (2023)
Abstract Background Conventional dissolving microneedles (DMNs) face significant challenges in anti-melanoma therapy due to the lack of active thrust to achieve efficient transdermal drug delivery and intra-tumoral penetration. Methods In this study,
Externí odkaz:
https://doaj.org/article/ca628dce71e14ac190ef5c0f3c17151e
Autor:
Wenting Su, Congyan Liu, Xi Jiang, Yanli Lv, Qin Chen, Jiachen Shi, Huangqin Zhang, Qiuling Ma, Chang Ge, Fei Kong, Xiaoqi Li, Yuping Liu, Yan Chen, Ding Qu
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Sustained retina drug delivery and rational drug combination are considered essential for enhancing the efficacy of therapy for wet age-related macular degeneration (wAMD) due to the conservative structure of the posterior ocular segment and
Externí odkaz:
https://doaj.org/article/344378800e674028a4f873bbc4df61f6
Publikováno v:
Drug Delivery, Vol 29, Iss 1, Pp 3454-3466 (2022)
Combinational icaritin (IC) and coix seed oil (CSO) holds promising potential in the treatment of hepatocellular carcinoma. However, traditional cocktail therapy is facing difficulties to optimize the synergistic antitumor efficacy due to the asynchr
Externí odkaz:
https://doaj.org/article/bf991adb1f6942bfa1f4dc59d21529de
Autor:
Jian Guo, Huating Zeng, Xinmeng Shi, Tao Han, Yimin Liu, Yuping Liu, Congyan Liu, Ding Qu, Yan Chen
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-19 (2022)
Abstract Cancer-associated fibroblasts (CAFs) deteriorate tumor microenvironment (TME) and hinder intra-tumoral drug delivery. Direct depleting CAFs exists unpredictable risks of tumor metastasis. Epithelial–mesenchymal transition (EMT) is a critic
Externí odkaz:
https://doaj.org/article/394d1010e2e544839211269a3208f80d
Autor:
Tao Han, Yan Sun, Xi Jiang, Chengming Gong, Fei Kong, Yi Luo, Chang Ge, Congyan Liu, Yuping Liu, Yanfei Mou, Huangqin Zhang, Jianming Ju, Yan Chen, Ding Qu
Publikováno v:
Theranostics; 2024, Vol. 14 Issue 15, p5883-5902, 20p
Publikováno v:
Drug Delivery, Vol 27, Iss 1, Pp 1608-1624 (2020)
The accumulation and penetration of antitumor drugs in tumor tissues are directly related to their antitumor effects. The particle size of the nanodrug delivery system is one of the most important factors for the accumulation and penetration of antit
Externí odkaz:
https://doaj.org/article/c99b0b3ed2864bca8b139bdbac3e1e27
Publikováno v:
Drug Delivery, Vol 24, Iss 1, Pp 10-19 (2017)
Multidrug resistance (MDR) is the major underlying cause of the low 5-year survival rate of esophageal carcinoma. In this study, we developed a novel microemulsion system (SD-ME) co-loaded with docetaxel (DTX) and Schizandrin A, a potent chemotherape
Externí odkaz:
https://doaj.org/article/4b6bbe5ce2814fc7809b1b02ec0c49c5
Publikováno v:
Drug Delivery, Vol 24, Iss 1, Pp 1179-1190 (2017)
Previously, we have developed a multicomponent-based microemulsion composed of etoposide, coix seed oil, and ginsenoside Rh2 (ECG-MEs). In this study, our goal was to validate the feasibility of ECG-MEs in lung cancer treatment and explore the mechan
Externí odkaz:
https://doaj.org/article/b0a02758f02b48ea8709ddb82634380c