EpCAM is critical for tumor proliferation and oxaliplatin chemoresistance in EpCAMhigh/CD44+ colorectal cancer stem cells

Autor: Qi Yanmei, Zhou Fengqiang, Geng Zhen, Ding Baozhong, Liu Lei

Publikováno v: Türk Biyokimya Dergisi, Vol 47, Iss 5, Pp 620-625 (2022)

A small subpopulation of colorectal cancer stem cells (CSCs) possess the ability to self-renew and the capacity to initiate the original tumor. EpCAMhigh/CD44+ cells are regarded as CSCs in colorectal cancer. The present study was undertaken to inves

Externí odkaz: https://doaj.org/article/13dea793ef3d46ec9f2ac92a4d1bf523

EpCAM is critical for tumor proliferation and oxaliplatin chemoresistance in EpCAM^high/CD44⁺ colorectal cancer stem cells.

Autor: Qi, Yanmei, Zhou, Fengqiang, Geng, Zhen, Ding, Baozhong, Liu, Lei

Publikováno v: Turkish Journal of Biochemistry / Turk Biyokimya Dergisi; Oct2022, Vol. 47 Issue 5, p620-625, 6p

Activation of Wnt/β-Catenin signaling in EpCAMhigh/CD44+ cells endow colorectal cancer with tumor proliferation and oxaliplatin chemoresistance.

Autor: Zhou F; Department of Gastrointestinal Surgery, Binzhou People's Hospital, Binzhou City, Shandong, 256600, China., Qi Y; Department of Gastroenterology, Binzhou People's Hospital, Binzhou City, Shandong, 256600, China., Geng Z; Department of Gastrointestinal Surgery, Binzhou People's Hospital, Binzhou City, Shandong, 256600, China., Ding B; Department of Gastrointestinal Surgery, Binzhou People's Hospital, Binzhou City, Shandong, 256600, China., Liu L; Department of Gastrointestinal Surgery, Binzhou People's Hospital, Binzhou City, Shandong, 256600, China.

Publikováno v: Combinatorial chemistry & high throughput screening [Comb Chem High Throughput Screen] 2023 Feb 09. Date of Electronic Publication: 2023 Feb 09.