Výsledky vyhledávání - "Dinesh Kumar Marimuthu"

Identifying amine fragments as potential inhibitors of acetylcholinesterase and butyrylcholinesterase through in silico analysis and validation through in vitro enzyme inhibition analysis

Autor: Saravanan Kandasamy, Chitra Loganathan, Penislusshiyan Sakayanathan, Karthikeyan Subramani, Dinesh Kumar Marimuthu, Saravanan Ravichandran, Vignesh Sivalingam, Palvannan Thayumanavan

Publikováno v: Alzheimer's & Dementia. 17

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6cc4dba148254abfb48f9f55e709d215
https://doi.org/10.1002/alz.052742

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In silico, theoretical biointerface analysis and in vitro kinetic analysis of amine compounds interaction with acetylcholinesterase and butyrylcholinesterase

Autor: Dinesh Kumar Marimuthu, Palvannan Thayumanavan, Penislusshiyan Sakayanathan, Arputharaj David Stephen, Vignesh Sivalingam, Saravanan Kandasamy, Subramani Karthikeyan, Saravanan Ravichandran, Chitra Loganathan

Publikováno v: International journal of biological macromolecules. 185

Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are considered important target for drug design against Alzheimer's disease. In the present study in silico analysis; theoretical analysis of biointerface between ligand and interacting ami

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e1ede6b56bcd8b585cebf20f5cf4619
https://pubmed.ncbi.nlm.nih.gov/34216669

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