Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Dinesh Cyanam"'
Autor:
Chen Zhao, Li Chen, Albrecht Stenzinger, Yali Li, Naiyer Rizvi, Jeff Allen, Matthew Hellmann, Diana M Merino, Lisa M McShane, David Fabrizio, Vincent Funari, Shu-Jen Chen, James R White, Paul Wenz, Jonathan Baden, J Carl Barrett, Ruchi Chaudhary, Wangjuh (Sting) Chen, Jen-Hao Cheng, Dinesh Cyanam, Jennifer S Dickey, Vikas Gupta, Elena Helman, Joerg Maas, Arnaud Papin, Rajesh Patidar, Katie J Quinn, Hongseok Tae, Christine Ward, Mingchao Xie, Ahmet Zehir, Manfred Dietel, Mark Stewart
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background Tumor mutational burden (TMB), defined as the number of somatic mutations per megabase of interrogated genomic sequence, demonstrates predictive biomarker potential for the identification of patients with cancer most likely to respond to i
Externí odkaz:
https://doaj.org/article/e8663839837544db9634250292b948f0
Autor:
Jan Budczies, David Fabrizio, H. Mellert, Mark Li, M. Butler, Phillip Stafford, K. Eyring, Diana Merino Vega, Mark Stewart, Dinesh Cyanam, Kristen Meier, Chen Zhao, Paul M. Williams, Justin Newberg, Warren Tom, Sarabjot Pabla, Ethan Sokol, A. Stenzinger, V.R. Gregersen, Vincent Funari, P. Beer, Roberto Salgado, Lisa M. McShane, G. Pestano, Jen-Hao Cheng, L.K. Bruce, Mingchao Xie, Laura M. Yee, J. Carl Barrett, Jeffrey M. Conroy, Laura Lasiter, R. Samara, Victor J. Weigman, George Green, Jonathan F. Baden, Tomas Vilimas, Jeff Allen, Matthew D. Hellmann, K.C. Valkenburg, Ahmet Zehir, A. J. Lazar, Elizabeth P. Garcia, Laura E. MacConaill, Laurel Keefer, Shu-Jen Chen, X.Z. Wang, Li Chen, A. Pallavajjalla, Yingdong Zhao, Q. Xie
Publikováno v:
Annals of Oncology. 32:1626-1636
Background Tumor mutational burden (TMB) measurements aid in identifying patients who are likely to benefit from immunotherapy; however, there is empirical variability across panel assays and factors contributing to this variability have not been com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::170bd38401051eeae84d71008ef32716
https://doi.org/10.1016/j.annonc.2021.09.016
https://doi.org/10.1016/j.annonc.2021.09.016
Autor:
Geoffrey Marc Lowman, Dinesh Cyanam, Emily Norris, Michelle Toro, Coleen Nemes, Tanaya Puranik, Yan Zhu, Alex Phan, Derek Wong, Portia Bernado, Anelia Kralcheva, Srinivas Nallandhighal, Loni Pickle, April Bigley, Mohit Gupta, Ying Jin, Sameh El-Difrawy, Amir Marcovitz, Fatima Zare, Charles Scafe, Yu-Ting Tseng, Jianjun Guo, Vinay Mittal, Scott Myrand, Santhoshi Bandla, Paul Williams, Eugene Ingerman, Elaine Wong-Ho, Seth Sadis, Mark Andersen, Rob Bennett
Publikováno v:
Cancer Research. 83:232-232
Introduction: We present the comprehensive genomic profiling performance of the Ion Torrent Genexus system using the Oncomine Comprehensive Assay Plus (OCA Plus), a 500+ gene targeted AmpliSeq-based oncology research panel that evaluates DNA variants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd54764013cb3c339e5004d1d254ee8e
https://doi.org/10.1158/1538-7445.am2023-232
https://doi.org/10.1158/1538-7445.am2023-232
Autor:
Kayla Zochowski, Dinesh Cyanam, Geoffrey Lowman, Jennifer Kilzer, Sameh El-Difrawy, Yan Zhu, Tanaya Puranik, Alex Phan, Derek Wong, Edith Kwong, Coleen Nemes, Iris Casuga, Frances Chan, Eun Ji Kim, Jianjun Guo, Vinay Mittal, Emily Norris, Shrutii Sarda, Mohit Gupta, Fan Shen, Steven Roman, Gabriel Vargas, Ying Jin, Annie Kraltcheva, Paul Williams, Amneet Gulati, Justin Rigby, Christopher Hoff, Richard Meade, Elaine Wong-Ho, Andrew Wong, Jamsheed Ghadiri, David Garcia-Viramontes, Scott Myrand, Seth Sadis
Publikováno v:
Cancer Research. 82:42-42
Introduction: The Ion Torrent Genexus System has redefined the genomic profiling paradigm as the first fully-integrated, next-generation sequencing (NGS) research platform to provide an automated sample-to-report workflow with results in a single day
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f64a840589b8bce9017a03091d3e6f35
https://doi.org/10.1158/1538-7445.am2022-42
https://doi.org/10.1158/1538-7445.am2022-42
Autor:
Fiona Hyland, Janice Au-Young, Vinay K. Mittal, Ruchi Chaudhary, Luca Quagliata, Dinesh Cyanam, Jermann Philip Martin, Ilaria Alborelli, Seth Sadis, Warren Tom
Publikováno v:
Translational lung cancer research. 7(6)
Background: Tumor mutational burden (TMB) is an increasingly important biomarker for immune checkpoint inhibitors. Recent publications have described strong association between high TMB and objective response to mono- and combination immunotherapies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5a23704e857391c0c7bca5eeb374ce6
https://pubmed.ncbi.nlm.nih.gov/30505706
https://pubmed.ncbi.nlm.nih.gov/30505706
Autor:
Santhoshi Bandla, Yu-Ting Tseng, Zheng Zang, Cristina Van Loy, James Veitch, Rajesh Gottimukkala, Amir Marcovitz, Elaine Wong-Ho, Warren Tom, Nickolay A. Khazanov, Gary Bee, Paul D. Williams, Janice Au-Young, Mohit Gupta, Dinesh Cyanam, Rose Putler, Sameh El-Difrawy, Aren Ewing, Anelia Kraltcheva, Seth Sadis, Scott P. Myrand, Vinay K. Mittal, Huimin Xie, J. Kilzer, Chenchen Yang
Publikováno v:
Cancer Research. 80:179-179
Comprehensive genomic profiling (CGP) of tumor samples by next-generation sequencing is used to support clinical and translational research into the genetic variants that serve as biomarkers for diagnosis, prognosis and potential therapeutic response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cc19c22ebb74f0aaf26fbe80695d036
https://doi.org/10.1158/1538-7445.am2020-179
https://doi.org/10.1158/1538-7445.am2020-179
Autor:
Vikas Gupta, Arnaud Papin, Warren Tom, Mingchao Xie, Elizabeth P. Garcia, Christopher D. Gocke, Lauryn Keeler, Jen-Hao Cheng, Laura E. MacConaill, Brett Kennedy, Lisa Haley, David Fabrizio, Ethan Sokol, Jeff Allen, Sean T. Glenn, Laurel Keefer, Jeffrey M. Conroy, J. Carl Barrett, Shu-Jen Chen, Matthew D. Hellmann, Laura M. Yee, Lisa M. McShane, Alexander J. Lazar, Diana M. Merino, Chen Zhao, Rajesh Patidar, Victor J. Weigman, Vincent Funari, Naiyer A. Rizvi, Kristen Meier, John F. Thompson, Kenneth R. Eyring, Tomas Vilimas, Mark Stewart, Dinesh Cyanam, Phillip Stafford, P. Mickey Williams
Publikováno v:
Cancer Research. 80:5671-5671
Introduction: Tumor mutational burden (TMB) is the number of somatic mutations per megabase in a tumor's genome and has shown promise as a predictive biomarker of response to immune checkpoint inhibitors across several cancers. TMB is typically measu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::408a09e39be3af6212ba7b51fcd191c8
https://doi.org/10.1158/1538-7445.am2020-5671
https://doi.org/10.1158/1538-7445.am2020-5671
Autor:
David Galimberti, Nikki Bonevich, Aisha Hunt, Jane Faershtein, Brooke McKnight, Jody McIntyre, Michael Hogan, Dinesh Cyanam, Nick Khazanov, Seth Sadis, Casey Gates, Sarah Anstead, Santhoshi Bandla, Joshua Holcomb, Jon Sherlock, Corina Nikoloff, Ken Kopp
Publikováno v:
Cancer Genetics. :S14-S15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b1e24f5ce4472b18350b0fc8789177f
https://doi.org/10.1016/j.cancergen.2019.04.041
https://doi.org/10.1016/j.cancergen.2019.04.041
Autor:
Nickolay A. Khazanov, Vinay K. Mittal, Scott P. Myrand, Seth Sadis, Amir Marcovitz, Paul D. Williams, Dinesh Cyanam, C. Van Loy, Christopher Allen, J. Kilzer, Fiona Hyland, G.G. Bee, Rajesh Gottimukkala, Elaine Wong-Ho
Publikováno v:
Annals of Oncology. 30:v766
Background Gene fusions caused by chromosomal rearrangements play an important role in oncogenesis, the progression of cancer and the selection of targeted therapies. Next-generation sequencing (NGS) using RNA enables sensitive, specific and precise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a42c421bb2035f5d8ada191aebdbbc99
https://doi.org/10.1093/annonc/mdz268.014
https://doi.org/10.1093/annonc/mdz268.014